Zobrazeno 1 - 10
of 203
pro vyhledávání: '"CEZARY CZAPLEWSKI"'
Autor:
Paula Roszczenko-Jasińska, Artur Giełdoń, Dominika Mazur, Marta Spodzieja, Maciej Plichta, Cezary Czaplewski, Wojciech Bal, Elzbieta K. Jagusztyn-Krynicka, Dariusz Bartosik
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2024)
Introduction:Helicobacter pylori is a bacterium that colonizes the gastric epithelium, which affects millions of people worldwide. H. pylori infection can lead to various gastrointestinal diseases, including gastric adenocarcinoma and mucosa-associat
Externí odkaz:
https://doaj.org/article/1b628f976fc34003815c9fe63d50ded5
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
In this paper we report the improvements and extensions of the UNRES server (https://unres-server.chem.ug.edu.pl) for physics-based simulations with the coarse-grained UNRES model of polypeptide chains. The improvements include the replacement of the
Externí odkaz:
https://doaj.org/article/3704a2487bc146ac996f336327ff6dd8
Publikováno v:
Biomolecules, Vol 13, Iss 6, p 941 (2023)
Molecular motors are essential for the movement and transportation of macromolecules in living organisms. Among them, rotatory motors are particularly efficient. In this study, we investigated the long-term dynamics of the designed left-handed alpha/
Externí odkaz:
https://doaj.org/article/bc5e920880a34a19b1ae31af38e0ccbc
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Many proteins can fold into well-defined conformations. However, intrinsically-disordered proteins (IDPs) do not possess a defined structure. Moreover, folded multi-domain proteins often digress into alternative conformations. Collectively, the confo
Externí odkaz:
https://doaj.org/article/6e60b07e33744aae96ee6cff26c2e30d
Publikováno v:
TASK Quarterly, Vol 2, Iss 4 (2021)
G protein-coupled receptors (GPCRs) are the most frequent targets for many drugs. They form the largest superfamily of integral membrane proteins, of which more than 1000 members have the following common features: (i) All GPCRs form 7 hydrophobic a-
Externí odkaz:
https://doaj.org/article/5c99a9f63efc406788559fd055fa5e5f
Autor:
Iga Biskupek, Cezary Czaplewski, Justyna Sawicka, Emilia Iłowska, Maria Dzierżyńska, Sylwia Rodziewicz-Motowidło, Adam Liwo
Publikováno v:
Biomolecules, Vol 12, Iss 8, p 1140 (2022)
The UNited RESidue (UNRES) model of polypeptide chains was applied to study the association of 20 peptides with sizes ranging from 6 to 32 amino-acid residues. Twelve of those were potentially aggregating hexa- or heptapeptides excised from larger pr
Externí odkaz:
https://doaj.org/article/1611e91a1d2a4d0e98b8d21de6cfd9a9
Publikováno v:
Molecules, Vol 27, Iss 7, p 2080 (2022)
The SARS-CoV-2 virus, commonly known as COVID-19, first occurred in December 2019 in Wuhan, Hubei Province, China. Since then, it has become a tremendous threat to human health. With a pandemic threat, it is in the significant interest of the scienti
Externí odkaz:
https://doaj.org/article/10b01cf6ead84042ac918cd0e249c191
Autor:
Chen Keasar, Liam J. McGuffin, Björn Wallner, Gaurav Chopra, Badri Adhikari, Debswapna Bhattacharya, Lauren Blake, Leandro Oliveira Bortot, Renzhi Cao, B. K. Dhanasekaran, Itzhel Dimas, Rodrigo Antonio Faccioli, Eshel Faraggi, Robert Ganzynkowicz, Sambit Ghosh, Soma Ghosh, Artur Giełdoń, Lukasz Golon, Yi He, Lim Heo, Jie Hou, Main Khan, Firas Khatib, George A. Khoury, Chris Kieslich, David E. Kim, Pawel Krupa, Gyu Rie Lee, Hongbo Li, Jilong Li, Agnieszka Lipska, Adam Liwo, Ali Hassan A. Maghrabi, Milot Mirdita, Shokoufeh Mirzaei, Magdalena A. Mozolewska, Melis Onel, Sergey Ovchinnikov, Anand Shah, Utkarsh Shah, Tomer Sidi, Adam K. Sieradzan, Magdalena Ślusarz, Rafal Ślusarz, James Smadbeck, Phanourios Tamamis, Nicholas Trieber, Tomasz Wirecki, Yanping Yin, Yang Zhang, Jaume Bacardit, Maciej Baranowski, Nicholas Chapman, Seth Cooper, Alexandre Defelicibus, Jeff Flatten, Brian Koepnick, Zoran Popović, Bartlomiej Zaborowski, David Baker, Jianlin Cheng, Cezary Czaplewski, Alexandre Cláudio Botazzo Delbem, Christodoulos Floudas, Andrzej Kloczkowski, Stanislaw Ołdziej, Michael Levitt, Harold Scheraga, Chaok Seok, Johannes Söding, Saraswathi Vishveshwara, Dong Xu, Foldit Players consortium, Silvia N. Crivelli
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-18 (2018)
Abstract Every two years groups worldwide participate in the Critical Assessment of Protein Structure Prediction (CASP) experiment to blindly test the strengths and weaknesses of their computational methods. CASP has significantly advanced the field
Externí odkaz:
https://doaj.org/article/b0b847aec1154062a3c86bac14d94e55
Autor:
Adam Liwo, Cezary Czaplewski, Adam K. Sieradzan, Agnieszka G. Lipska, Sergey A. Samsonov, Rajesh K. Murarka
Publikováno v:
Biomolecules, Vol 11, Iss 9, p 1347 (2021)
Molecular dynamics with coarse-grained models is nowadays extensively used to simulate biomolecular systems at large time and size scales, compared to those accessible to all-atom molecular dynamics. In this review article, we describe the physical b
Externí odkaz:
https://doaj.org/article/e7ff07350cd848e6afbc2b062b474009
Autor:
Magdalena Joanna Grzeszczuk, Aleksandra Bąk, Anna Marta Banaś, Paweł Urbanowicz, Stanislaw Dunin-Horkawicz, Artur Gieldon, Cezary Czaplewski, Adam Liwo, Elżbieta K Jagusztyn-Krynicka
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195358 (2018)
Helicobacter pylori HP0377 is a thiol oxidoreductase, a member of the CcmG family involved in cytochrome biogenesis, as previously shown by in vitro experiments. In this report, we document that HP0377 also acts in vivo in the cytochrome assembly pro
Externí odkaz:
https://doaj.org/article/dd5ea5637b1f4ab8a74da0dfc3cc10b2