Expression of simian CETP in normolipidemic Fisher rats has a profound effect on large sized apoE-containing HDL

Autor: Zoulika Zak, Laurent Lagrost, Thomas Gautier, David Masson, Valérie Deckert, Linda Duverneuil, Jean-Paul Pais de Barros, Naig Le Guern, Laure Dumont, Martina Schneider, Valérie Risson, Philippe Moulin, Delphine Autran, Gillian Brooker, Jean Sassard, Alain Bataillard

Publikováno v: Journal of Lipid Research, Vol 43, Iss 12, Pp 2164-2171 (2002)

In order to investigate the direct effect of cholesteryl ester transfer protein (CE22285) on the structure and composition of HDL in vivo, simian CETP was expressed in Fisher rat that spontaneously displays high plasma levels of HDL1. In the new CETP

Externí odkaz: https://doaj.org/article/66dbab9581da475e9df0b98d61be5f7f

Cholesteryl Ester Transfer Protein (CETP) Deficiency and CETP Inhibitors

Autor: Atsushi Nohara, Hiroshi Mabuchi, Akihiro Inazu

Publikováno v: Molecules and Cells

Epidemiologic studies have shown that low-density lipoprotein cholesterol (LDL-C) is a strong risk factor, whilst high-density lipoprotein cholesterol (HDL-C) reduces the risk of coronary heart disease (CHD). Therefore, strategies to manage dyslipide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c2994539c4c69fcd14a3e054d75d56
https://doi.org/10.14348/molcells.2014.0265

A review of CETP and its relation to atherosclerosis

Autor: John J.P. Kastelein, Anke H.E.M. Klerkx, Erik S.G. Stroes, Anton F. H. Stalenhoef, Greetje J. de Grooth, Jan Albert Kuivenhoven

Publikováno v: Journal of Lipid Research, 45, 11, pp. 1967-74
Journal of Lipid Research, 45, 1967-74
Journal of Lipid Research, Vol 45, Iss 11, Pp 1967-1974 (2004)

Contains fulltext : 57477.pdf (Publisher’s version ) (Open Access) Although the atheroprotective role of HDL cholesterol (HDL-c) is well documented, effective therapeutics to selectively increase plasma HDL-c levels are not yet available. Recent pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac004fb6f79494431028ffe0bd874f2
https://doi.org/10.1194/jlr.r400007-jlr200

Abstract 20674: Genetic CETP Deficiency Associated With Higher eGFR and Lower Coronary Stenosis Index in Dyslipdemic Patients in Japan

Autor: Hayato Tada, Atsushi Nohara, Mie Yoshida, Chiaki Nakanishi, Akihiro Inazu, Masa-aki Kawashiri, Mika Mori, Satoko Okazaki, Kunimasa Yagi, Hiroshi Mabuchi, Masakazu Yamagishi

Publikováno v: Circulation. 130

Background: It is still controversial whether lower CETP is anti-atherogenic or not. Genetic deficiency should have greater impact on clinical course because its lifetime long effect. We evaluated impact of CETP deficiency on coronary atherosclerosis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a10f31b1c0c3ddc5e6ed46e540ea31ef
https://doi.org/10.1161/circ.130.suppl_2.20674

Different effects of compounds decreasing cholesteryl ester transfer protein activity on lipoprotein metabolism

Autor: Eric J. Niesor

Publikováno v: Current opinion in lipidology. 22(4)

Review literature on the effect of decreasing cholesteryl ester transfer protein (CETP) activity through pharmacological inhibition or modulation in preclinical and clinical settings compared to human CETP deficiency on lipoprotein characteristics, H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1ddd10e28271724135f3f1b19bd1767
https://pubmed.ncbi.nlm.nih.gov/21587074