G4C2 repeat affects nuclear mRNA export pathway in a cellular model of C9orf72-ALS

Autor: ROSSI S 1, SERRANO A 1, MIRRA A 2, 3, CESTRA G 4, CARRÌ MT 2, COZZOLINO M 1

Publikováno v: info:cnr-pdr/source/autori:ROSSI S 1, SERRANO A 1, MIRRA A 2,3, CESTRA G 4, CARRÌ MT 2,3, COZZOLINO M 1,3/congresso_nome:10th FENS FORUM of NEUROSCIENCE/congresso_luogo:COPENHAGEN, DENMARK/congresso_data:02-06%2F07%2F2016/anno:2016/pagina_da:/pagina_a:/intervallo_pagine

Aims: A non-coding GGGGCC (G4C2) repeat expansion in C9orf72 gene is the most frequent cause of Amyotrophic Lateral Sclerosis (ALS). RNAs containing the repeat, which accumulate as RNA foci in the nucleus and/or cytoplasm of affected cells, bind to v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::c735d7d041aa7f6c49c3f5af7c5bcb05
https://publications.cnr.it/doc/369783