A novel microRNA boosts hyper-β-oxidation of fatty acids in liver by impeding CEP350-mediated sequestration of PPARα and thus restricts chronic hepatitis C

Autor: Joyeeta Chakraborty, Suchandrima Ghosh, Abhijit Chowdhury, Susree Roy, Sayantani Bhowmik, Raghunath Chatterjee, Simanti Datta, Avijit Goswami, Suvendra N. Bhattacharyya, Priyanka Kumari, Sakshi Dokania, Amit Ghosh, Soma Banerjee

Publikováno v: RNA Biol

Imbalance in lipid metabolism induces steatosis in liver during Chronic hepatitis C (CHC). Contribution of microRNAs in regulating lipid homoeostasis and liver disease progression is well established using small RNA-transcriptome data. Owing to the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72d40e9afbb922aaebdb441d4bcfea13
https://doi.org/10.1080/15476286.2020.1768353

Author response: CEP78 functions downstream of CEP350 to control biogenesis of primary cilia by negatively regulating CP110 levels

Autor: André Brás Gonçalves, Jens S. Andersen, Catja Weiss, Mathieu Quinodoz, Carlo Rivolta, Konstantinos Nikopoulos, Søren T. Christensen, Sarah Kirstine Hasselbalch, Beinta Biskopstø Joensen, Magnus Per Damsø Jeppesen, Signe Krogh Ohlsen, Reem Suleiman, Pernille Martens, Sebastian Patzke, Pietro Farinelli, Lotte B. Pedersen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2944669af0732f969163d55a9067765f
https://doi.org/10.7554/elife.63731.sa2

The effect of Diosmin on the blood proteome in a rat model of venous thrombosis

Autor: Yongzhi Li, Hong Zhang, Cuilin Cheng, Yingyu Zhou, Weihong Lu, Lei Yao

Publikováno v: International journal of biological macromolecules. 104

Diosmin is the aglycone moiety of diosmetin (3',5,7 trihydroxy-4'methoxy radicals flavonoids), a naturally occurring flavone glycoside, whose antithrombotic effect was studied in rats. This study was designed to find the protein changes of venous thr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6399c1ba1698686e66abedfcf6f30e01
https://pubmed.ncbi.nlm.nih.gov/28606843

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CEP78 functions downstream of CEP350 to control biogenesis of primary cilia by negatively regulating CP110 levels.

Autor: Gonçalves AB; Department of Biology, Section for Cell Biology and Physiology, University of Copenhagen, Copenhagen, Denmark., Hasselbalch SK; Department of Biology, Section for Cell Biology and Physiology, University of Copenhagen, Copenhagen, Denmark., Joensen BB; Department of Biology, Section for Cell Biology and Physiology, University of Copenhagen, Copenhagen, Denmark., Patzke S; Department of Radiation Biology, Institute for Cancer Research, Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway., Martens P; Department of Biology, Section for Cell Biology and Physiology, University of Copenhagen, Copenhagen, Denmark., Ohlsen SK; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark., Quinodoz M; Institute of Molecular and Clinical Ophthalmology Basel (IOB), Basel, Switzerland.; Department of Ophthalmology, University of Basel, Basel, Switzerland.; Department of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom., Nikopoulos K; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland., Suleiman R; Department of Biology, Section for Cell Biology and Physiology, University of Copenhagen, Copenhagen, Denmark., Damsø Jeppesen MP; Department of Biology, Section for Cell Biology and Physiology, University of Copenhagen, Copenhagen, Denmark., Weiss C; Department of Biology, Section for Cell Biology and Physiology, University of Copenhagen, Copenhagen, Denmark., Christensen ST; Department of Biology, Section for Cell Biology and Physiology, University of Copenhagen, Copenhagen, Denmark., Rivolta C; Institute of Molecular and Clinical Ophthalmology Basel (IOB), Basel, Switzerland.; Department of Ophthalmology, University of Basel, Basel, Switzerland.; Department of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom., Andersen JS; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark., Farinelli P; Department of Biology, Section for Cell Biology and Physiology, University of Copenhagen, Copenhagen, Denmark., Pedersen LB; Department of Biology, Section for Cell Biology and Physiology, University of Copenhagen, Copenhagen, Denmark.

Publikováno v: ELife [Elife] 2021 Jul 14; Vol. 10. Date of Electronic Publication: 2021 Jul 14.