Zobrazeno 1 - 10
of 71
pro vyhledávání: '"CENPE"'
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-12 (2024)
Abstract Background Gastric cancer (GC) is a prevalent type of malignant gastrointestinal tumor. Many studies have shown that CENPE acts as an oncogene in some cancers. However, its expression level and clinical value in GC are not clear. Methods Obt
Externí odkaz:
https://doaj.org/article/c5ee9beeb7dc4b12b2e8a3361e203fd9
Publikováno v:
European Journal of Medical Research, Vol 28, Iss 1, Pp 1-13 (2023)
Abstract Background Most sarcomatoid differentiated renal cell carcinoma was differentiated from Chromophobe renal cell carcinoma (KICH) and related to a bad prognosis. Thus, finding biomarkers is important for the therapy of KICH. Methods The UCSC w
Externí odkaz:
https://doaj.org/article/c418e502a04b464c8ce013efe5729105
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundNon-WNT/non-SHH medulloblastoma (MB) is one of the subtypes with the highest genetic heterogeneity in MB, and its current treatment strategies have unsatisfactory results and significant side effects. As a member of the centromere protein (
Externí odkaz:
https://doaj.org/article/5ec68688e2394fdda0fa082ba2bebb21
Akademický článek
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Akademický článek
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Autor:
Bárbara Pinto, João P. N. Silva, Patrícia M. A. Silva, Daniel José Barbosa, Bruno Sarmento, Juliana Carvalho Tavares, Hassan Bousbaa
Publikováno v:
Pharmaceutics, Vol 16, Iss 1, p 56 (2023)
Antimitotic compounds, targeting key spindle assembly checkpoint (SAC) components (e.g., MPS1, Aurora kinase B, PLK1, KLP1, CENPE), are potential alternatives to microtubule-targeting antimitotic agents (e.g., paclitaxel) to circumvent resistance and
Externí odkaz:
https://doaj.org/article/2ebe4a5eb1f54f99997c38cb49ff19a1
Autor:
Mingyue Shi, Junwei Niu, Xiaona Niu, Honggang Guo, Yanliang Bai, Jie Shi, Weiya Li, Kai Sun, Yuqing Chen, Fengmin Shao
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The prognosis of chemoresistant acute myeloid leukemia (AML) is still poor, mainly owing to the sustained proliferation ability of leukemic cells, while the microtubules have a major role in sustaining the continuity of cell cycle. In the present stu
Externí odkaz:
https://doaj.org/article/cfa642e22dfe4ac6b60f058668cc5dd0
Autor:
Hao Xuezhi, Qu Tao
Publikováno v:
Open Medicine, Vol 14, Iss 1, Pp 497-502 (2019)
Non-small cell lung cancer (NSCLC) is one of the most important causes of death worldwide. Most patients are diagnosed in the advanced stage and have a poor prognosis. This study was to investigate the expression and significance of CENPE in NSCLC.
Externí odkaz:
https://doaj.org/article/b483b241dcc645fd826d4aa8e01185e6
Akademický článek
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Autor:
Taryne Chong, Amila Sarac, Cindy Q. Yao, Linda Liao, Nicola Lyttle, Paul C. Boutros, John M. S. Bartlett, Melanie Spears
Publikováno v:
Journal of Ovarian Research, Vol 11, Iss 1, Pp 1-9 (2018)
Abstract Background Ovarian cancer is the leading gynecologic cancer diagnosed in North America and because related symptoms are not disease specific, this often leads to late detection, an advanced disease state, and the need for chemotherapy. Ovari
Externí odkaz:
https://doaj.org/article/d532563778fa47cdaa8d9f2b318f175c