Zobrazeno 1 - 10
of 16 022
pro vyhledávání: '"CELLULAR UPTAKE"'
Publikováno v:
BMC Medical Imaging, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Introduction The treatment of preinvasive lesions is more effective than treating invasive disease, hence detecting cancer at its early stages is crucial. However, currently, available screening methods show various limitations in terms of s
Externí odkaz:
https://doaj.org/article/6df1dd30356148f08bf579024dbf5d44
Autor:
Ali-Jerman H, Al-Quraishi Z, Muglikar A, Perrie Y, Tate RJ, Mullin M, McNeill G, Mackenzie G, Dufès C
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 12189-12203 (2024)
Hawraa Ali-Jerman,1 Zainab Al-Quraishi,1 Ashish Muglikar,1 Yvonne Perrie,1 Rothwelle J Tate,1 Margaret Mullin,2 Gayle McNeill,1 Graeme Mackenzie,1 Christine Dufès1 1Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde
Externí odkaz:
https://doaj.org/article/92cf3bf0b64c4689b50e98ad77e84569
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 10, Pp 11031-11047 (2024)
Oligonucleotides have been identified as powerful therapeutics for treating genetic disorders and diseases related to epigenetic factors such as metabolic and immunological dysfunctions. However, they face certain obstacles in terms of limited delive
Externí odkaz:
https://doaj.org/article/a5e3e83b6ad440e58d047f5b4fb36b19
Autor:
Manuela Milden-Appel, Markus Paravicini, Jannick P. Milden, Martin Schüßler, Rolf Jakoby, M. Cristina Cardoso
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Delivering foreign molecules and genetic material into cells is a crucial process in life sciences and biotechnology, resulting in great interest in effective cell transfection methods. Importantly, physical transfection methods allow delive
Externí odkaz:
https://doaj.org/article/effca155ef194adbab73938dc884e985
Publikováno v:
Drugs and Drug Candidates, Vol 3, Iss 3, Pp 566-597 (2024)
Docetaxel (DTX) and betulinic acid (BA) co-encapsulated poly-lactic co-glycolic acid (PLGA) nanoparticles (NPs) were developed for enhanced lung cancer activity in vitro. Poly (lactic-co-glycolic acid) (PLGA) was used as an encapsulating polymer alon
Externí odkaz:
https://doaj.org/article/a22943e99f6940eaa1fca63257465a45
Publikováno v:
Ceramics-Silikáty, Vol 68, Iss 3, Pp 400-408 (2024)
The high biocompatibility, wear resistance, and high surface area-to-volume ratios of calcium phosphate (CaP) nanoparticles make them materials of great interest for a very broad range of medical applications, such as dentistry, drug delivery, biomed
Externí odkaz:
https://doaj.org/article/b48d08eaf8b746bfaa62d05e31007076
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 15, Iss 1, Pp 909-924 (2024)
Nanoparticles (NPs) are considered as versatile tools in various fields including medicine, electronics, and environmental science. Understanding the structural aspects of surface modifiers in nanoparticles that govern their cellular uptake is crucia
Externí odkaz:
https://doaj.org/article/6969e3fb95574f2694a6fec9178f4765
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The α-helical antimicrobial peptide Kn2-7 enhances the activation of mouse macrophage-like RAW264.7 induced by DNA containing unmethylated cytosine-guanine motifs (CpG DNA). This enhancement is related to increased cellular uptake of DNA by
Externí odkaz:
https://doaj.org/article/b0e292b4eefe4539b52cd6ac482ef70d
Publikováno v:
ChemistryEurope, Vol 2, Iss 5, Pp n/a-n/a (2024)
Abstract Dynamic‐covalent electrophiles called cascade exchangers (CAXs) can reversibly engage cell‐surface thiols. Conjugates between CAXs and molecular or even protein‐sized cargos can deliver these cargos into cells by thiol‐mediated uptak
Externí odkaz:
https://doaj.org/article/7377e0a9702640b28b2ba46709316e66
Autor:
Farhan Haq, Samudra Sabari, Jaromir Háček, Antonín Brisuda, Ines Ambite, Michele Cavalera, Parisa Esmaeili, Murphy Lam Yim Wan, Shahram Ahmadi, Marek Babjuk, Catharina Svanborg
Publikováno v:
Cancer Medicine, Vol 13, Iss 17, Pp n/a-n/a (2024)
Abstract Background The tumoricidal complex alpha1‐oleate targets bladder cancer cells, triggering rapid, apoptosis‐like tumor cell death. Clinical effects of alpha1‐oleate were recently observed in patients with non‐muscle invasive bladder c
Externí odkaz:
https://doaj.org/article/b5d29c498cd44e9d837e274d4f7f27ed