Targeted Vpr-derived Peptides Reach Mitochondria to Induce Apoptosis of aVb3-Expressing Endothelial Cells

Autor: Pierre Rustin, Etienne Jacotot, Dominique Rebouillat, J. Brière, Hervé Lecoeur, Déas O, Deniaud A, Myriam Lassalle, Johan Hoebeke, Lena Edelman, Christine Péchoux, D. Chauvier, Magali Brabant, Roux P, Brenner C, Dupont S, Baux L, Alain Langonne, J. P. Briand, A. Borgne-Sanchez

Publikováno v: Cell Death and Differentiation
Cell Death and Differentiation, Nature Publishing Group, 2006, 14, pp.422-35
Cell Death and Differentiation, Nature Publishing Group, 2007, 14, pp.422-435. ⟨10.1038/sj.cdd.4402018⟩
Cell Death and Differentiation, Nature Publishing Group, 2007, 14 (3), pp.422-35. ⟨10.1038/sj.cdd.4402018⟩
Cell Death and Differentiation, 2007, 14 (3), pp.422-35. ⟨10.1038/sj.cdd.4402018⟩

International audience; The HIV-1 encoded apoptogenic protein Vpr induces mitochondrial membrane permeabilization (MMP) via interactions with the voltage-dependent anion channel (VDAC) and the adenine nucleotide translocator (ANT). We have designed a

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https://hal.archives-ouvertes.fr/hal-00172556