Zobrazeno 1 - 10
of 40
pro vyhledávání: '"CE cholesteryl ester"'
Autor:
Fei Luo, Eriks Smagris, Sarah A. Martin, Goncalo Vale, Jeffrey G. McDonald, Justin A. Fletcher, Shawn C. Burgess, Helen H. Hobbs, Jonathan C. Cohen
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 879-899 (2022)
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 879-899 (2022)
Background & Aims: Substitution of lysine for glutamic acid at residu 167 in Transmembrane 6 superfamily member 2 (TM6SF2) is associated with fatty liver disease and reduced plasma lipid levels. Tm6sf2-/- mice replicate the human phenotype but were n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c501eab0983bab28ced1482110d3291c
http://europepmc.org/articles/PMC8804273
http://europepmc.org/articles/PMC8804273
Autor:
Aldons J. Lusis, Raquel Floyd, Simon Sabir, Miklós Péterfy, Paola León-Mimila, Anthony E. Jones, Linsey Stiles, Dulshan W. Jayasekera, Samuel Canizales-Quinteros, Adriana Huertas-Vazquez, Varun Shravah, Angel A. Cortez, Karthickeyan Chella Krishnan, Ajit S. Divakaruni
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and molecular gastroenterology and hepatology, vol 11, iss 2
Cellular and molecular gastroenterology and hepatology, vol 11, iss 2
Background & Aims The etiology of nonalcoholic fatty liver disease (NAFLD) is poorly understood, with males and certain populations exhibiting markedly increased susceptibility. Using a systems genetics approach involving multi-omic analysis of ∼10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd4127e52760363929df8a11fd651eca
http://europepmc.org/articles/PMC7788245
http://europepmc.org/articles/PMC7788245
Autor:
Cécile Gladine, Maria Fedorova
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab
Journal of Mass Spectrometry and Advances in the Clinical Lab, 2021, 21, pp.27-30. ⟨10.1016/j.jmsacl.2021.08.003⟩
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 21, Iss, Pp 27-30 (2021)
Journal of Mass Spectrometry and Advances in the Clinical Lab, 2021, 21, pp.27-30. ⟨10.1016/j.jmsacl.2021.08.003⟩
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 21, Iss, Pp 27-30 (2021)
International audience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9276fa1e85369b86a9a3aec51ea7c48b
https://hal.inrae.fr/hal-03497751
https://hal.inrae.fr/hal-03497751
Hepatic lysosomal acid lipase overexpression worsens hepatic inflammation in mice fed a Western diet
Autor:
Gavin Fredrickson, Fanta Barrow, Michael W. Lopresti, Douglas G. Mashek, Arnav S. Desai, Xavier S. Revelo, Breann Abernathy, Wenqi Cui
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, Vol 62, Iss, Pp 100133-(2021)
Journal of Lipid Research, Vol 62, Iss, Pp 100133-(2021)
Nonalcoholic fatty liver disease (NAFLD) is characterized by the accumulation of lipid droplets in hepatocytes. NAFLD development and progression is associated with an increase in hepatic cholesterol levels and decreased autophagy and lipophagy flux.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c73a9fbcf47ac6bf68281ac21b125829
https://pubmed.ncbi.nlm.nih.gov/34624333
https://pubmed.ncbi.nlm.nih.gov/34624333
Autor:
Yishi Shen, Shucun Qin, Bingxiang Wang, Yongfang Zhao, Lei Zhai, Boyan Liu, Xiaole Chang, Adekunle Alabi, Shijun Deng, Maggie Wang, Hong-mei Gu, Da-Wei Zhang, Xiao-dan Xia, Guiqing Wang, Sijie Xing
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, Vol 62, Iss, Pp 100091-(2021)
Journal of Lipid Research, Vol 62, Iss, Pp 100091-(2021)
Plasma LDL is produced from catabolism of VLDL and cleared from circulation mainly via the hepatic LDL receptor (LDLR). Proprotein convertase subtilisin/kexin type 9 (PCSK9) promotes LDLR degradation, increasing plasma LDL-C levels. Circulating PCSK9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ace96902105c8bd0f6e5ca427b95574
http://europepmc.org/articles/PMC8261665
http://europepmc.org/articles/PMC8261665
Autor:
Suze-Anne Korteland, Gijs van Soest, Mirjam Visscher, Kim Van der Heiden, Sophinese Iskander-Rizk, Astrid M. Moerman, Antonius F.W. van der Steen
Publikováno v:
Photoacoustics
Photoacoustics, 22:100261. Elsevier GmbH
Photoacoustics, Vol 22, Iss, Pp 100261-(2021)
Photoacoustics, 22:100261. Elsevier GmbH
Photoacoustics, Vol 22, Iss, Pp 100261-(2021)
Highlights • We built a micro-spectroscopic photoacoustic imaging setup, allowing spectral imaging throughout the section. • Spectral differences were primarily due to differences in hydrocarbon chain length and number of unsaturated bonds. • P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b85cb9a3a0d5d27922aa6847ff8be41b
https://pure.eur.nl/en/publications/160b741a-dc8e-4717-b624-058a2a2d13f3
https://pure.eur.nl/en/publications/160b741a-dc8e-4717-b624-058a2a2d13f3
Autor:
N. Thao N. Galvan, Mercedes Barzi, John A. Goss, William R. Lagor, David D. Moore, Adam Dean, Neil J. McKenna, Pavel Sumazin, Barry Zorman, Diane Yang, Beatrice Bissig-Choisat, Karl-Dimiter Bissig, Xavier Legras, David E. Cohen, Robert Brian York, Malgorzata Borowiak, Michele Alves-Bezerra, Scott A. Ochsner
Publikováno v:
JHEP reports : innovation in hepatology, vol 3, iss 3
JHEP Reports
JHEP Reports, Vol 3, Iss 3, Pp 100281-(2021)
JHEP Reports
JHEP Reports, Vol 3, Iss 3, Pp 100281-(2021)
Background & Aims The accumulation of neutral lipids within hepatocytes underlies non-alcoholic fatty liver disease (NAFLD), which affects a quarter of the world’s population and is associated with hepatitis, cirrhosis, and hepatocellular carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b0393a5555874a5526c491b8421dfd
https://escholarship.org/uc/item/2hg8h2x9
https://escholarship.org/uc/item/2hg8h2x9
Autor:
Antonius Fw van der Steen, Hence J.M. Verhagen, Mirjam Visscher, Nuria Slijkhuis, Peter C. Burgers, Heleen M.M. van Beusekom, Theo Klein, Astrid M. Moerman, Kim Van der Heiden, Yolanda B. de Rijke, Kim van Gaalen, Gijs van Soest, Bram Heijs, Theo M. Luider, Frank J. H. Gijsen
Publikováno v:
Journal of Lipid Research, Vol 62, Iss, Pp 100020-(2021)
Journal of Lipid Research
Journal of Lipid Research, 62. ELSEVIER
Journal of Lipid Research, 62:100020. American Society for Biochemistry and Molecular Biology Inc.
Journal of Lipid Research
Journal of Lipid Research, 62. ELSEVIER
Journal of Lipid Research, 62:100020. American Society for Biochemistry and Molecular Biology Inc.
Carotid atherosclerosis is a risk factor for ischemic stroke, one of the main causes of mortality and disability worldwide. The disease is characterized by plaques, heterogeneous deposits of lipids, and necrotic debris in the vascular wall, which gro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d440cac86ce846438ba8fc6a1578790
https://hdl.handle.net/1887/3246770
https://hdl.handle.net/1887/3246770
Autor:
Sven Göpel, G. Hege Thoresen, Xiao-Rong Peng, Hege G. Bakke, Eili Tranheim Kase, Per Kristian Lunde, Jenny Lund, Lars Eide, Roya Ghobadi, Arild C. Rustan, Gavin O’ Mahony, Parmeshwar B. Katare, Abel M. Mengeste
Publikováno v:
Current Research in Pharmacology and Drug Discovery, Vol 2, Iss, Pp 100060-(2021)
Current Research in Pharmacology and Drug Discovery
Current Research in Pharmacology and Drug Discovery
Background and objective A number of studies have highlighted muscle-specific mechanisms of thermogenesis involving futile cycling of Ca2+ driven by sarco (endo)plasmic reticulum Ca2+-ATPase (SERCA) and generating heat from ATP hydrolysis to be a pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9eb79b1aa486f3fccd8e118dcb4a026
http://www.sciencedirect.com/science/article/pii/S259025712100047X
http://www.sciencedirect.com/science/article/pii/S259025712100047X
Autor:
Ralph Burkhardt, Gerhard Liebisch, Christer S. Ejsing, Sabrina Krautbauer, Marcus Höring, Verena M. Ertl
Publikováno v:
Journal of Lipid Research, Vol 62, Iss, Pp 100050-(2021)
Höring, M, Ejsing, C S, Krautbauer, S, Ertl, V M, Burkhardt, R & Liebisch, G 2021, ' Accurate quantification of lipid species affected by isobaric overlap in Fourier-transform mass spectrometry ', Journal of Lipid Research, vol. 62, 100050 . https://doi.org/10.1016/j.jlr.2021.100050
Journal of Lipid Research
Höring, M, Ejsing, C S, Krautbauer, S, Ertl, V M, Burkhardt, R & Liebisch, G 2021, ' Accurate quantification of lipid species affected by isobaric overlap in Fourier-transform mass spectrometry ', Journal of Lipid Research, vol. 62, 100050 . https://doi.org/10.1016/j.jlr.2021.100050
Journal of Lipid Research
Lipidomics data require consideration of ions with near-identical masses, which comprises among others the Type-II isotopic overlap. This overlap occurs in series of lipid species differing only by number of double bonds (DBs) mainly because of the n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfd7c60b35340106caa9ccd4904c157f
http://www.sciencedirect.com/science/article/pii/S0022227521000304
http://www.sciencedirect.com/science/article/pii/S0022227521000304