Výsledky vyhledávání - "CE Van der Schoot"

Deficiency of glycosyl-phosphatidylinositol-linked membrane glycoproteins of leukocytes in paroxysmal nocturnal hemoglobinuria, description of a new diagnostic cytofluorometric assay

Autor: CE van der Schoot, TW Huizinga, ET van 't Veer-Korthof, R Wijmans, J Pinkster, AE von dem Borne

Publikováno v: Blood. 76:1853-1859

Paroxysmal nocturnal hemoglobinuria (PNH) is a disease that affects not only red cells, but other blood cells as well. The common defect is supposed to be an acquired deficiency of glycosyl-phosphatidylinositol (GPI)-anchored membrane proteins, which

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c291e7465df70b39579a45eaed9d97d4
https://doi.org/10.1182/blood.v76.9.1853.bloodjournal7691853

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Recombinant granulocyte colony-stimulating factor administration to healthy volunteers: induction of immunophenotypically and functionally altered neutrophils via an effect on myeloid progenitor cells

Autor: JM Kerst, M de Haas, CE van der Schoot, IC Slaper-Cortenbach, M Kleijer, AE von dem Borne, RH van Oers

Publikováno v: Blood. 82(11)

We performed a detailed kinetic study on the in vivo effect of a single subcutaneous dose of granulocyte colony-stimulating factor (G-CSF; 300 micrograms) in four healthy individuals on the expression and function of neutrophil Fc gamma receptors (Fc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c551fd2894003e6566b8edd86a81ddf
https://pubmed.ncbi.nlm.nih.gov/7694676

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Expression and release of CD27 in human B-cell malignancies

Autor: MH van Oers, ST Pals, LM Evers, CE van der Schoot, G Koopman, JM Bonfrer, RQ Hintzen, AE von dem Borne, RA van Lier

Publikováno v: Blood. 82(11)

CD27, a transmembrane disulfide-linked 55-kD homodimer, belongs to the nerve growth factor-receptor family, a group of homologous molecules involved in lymphocyte differentiation and selection. It is expressed on mature thymocytes, peripheral blood T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eeaa9e0cc60e4ea36eeab5f705a01ce
https://pubmed.ncbi.nlm.nih.gov/8241510

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Human myeloid alpha 3-fucosyltransferase is involved in the expression of the sialyl-Lewis(x) determinant, a ligand for E- and P-selectin

Autor: EW Easton, WE Schiphorst, E van Drunen, CE van der Schoot, DH van den Eijnden

Publikováno v: Blood. 81(11)

The sialyl-Lex determinant (NeuAc alpha 2-->3Gal beta 1-->4[Fuc alpha- 1-->3]GlcNAc) has been identified as a major ligand in the selectin- mediated adhesion of neutrophils and monocytes to activated endothelium or platelets. This carbohydrate epitop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7d67c54c0921dcd741188b4269cd9dc
https://pubmed.ncbi.nlm.nih.gov/7684623

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Acute myeloid leukemia M4 with bone marrow eosinophilia (M4Eo) and inv(16)(p13q22) exhibits a specific immunophenotype with CD2 expression

Autor: HJ Adriaansen, PA te Boekhorst, AM Hagemeijer, CE van der Schoot, HR Delwel, JJ van Dongen

Publikováno v: Blood. 81(11)

Extensive immunologic marker analysis was performed to characterize the various leukemic cell populations in eight patients with inv(16)(p13q22) in association with acute myeloid leukemia with abnormal bone marrow eosinophilia (AML-M4Eo). The eight A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbdee0664a9e80c833131a7ea850ead4
https://pubmed.ncbi.nlm.nih.gov/8098967

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Granulocyte colony-stimulating factor induces hFc gamma RI (CD64 antigen)-positive neutrophils via an effect on myeloid precursor cells

Autor: JM Kerst, JG van de Winkel, AH Evans, M de Haas, IC Slaper-Cortenbach, TP de Wit, AE von dem Borne, CE van der Schoot, RH van Oers

Publikováno v: Blood. 81(6)

In this study we have examined hFc gamma RI expression during myelopoiesis. Normal bone marrow (BM) cells were found to express hFc gamma RI up to the metamyelocyte stage. A different Fc gamma RI expression pattern was observed in an in vitro model o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe3ddb93253f48e61c031835c207bc4
https://pubmed.ncbi.nlm.nih.gov/7680917

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Alpha 4 beta 1 and alpha 5 beta 1 are differentially expressed during myelopoiesis and mediate the adherence of human CD34+ cells to fibronectin in an activation-dependent way

Autor: JM Kerst, JB Sanders, IC Slaper-Cortenbach, MC Doorakkers, B Hooibrink, RH van Oers, AE von dem Borne, CE van der Schoot

Publikováno v: Blood. 81(2)

To study the receptors involved in the interaction between extracellular matrix proteins and hematopoietic progenitor cells, we analyzed the expression of beta 1 integrins on CD34+ bone marrow cells by means of immunoflowcytometry. Alpha 4 beta 1 and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3426f0b8e1a00c95b407a11b97bffb03
https://pubmed.ncbi.nlm.nih.gov/7678511

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Membrane surface antigen expression on neutrophils: a reappraisal of the use of surface markers for neutrophil activation

Autor: TW Kuijpers, AT Tool, CE van der Schoot, LA Ginsel, JJ Onderwater, D Roos, AJ Verhoeven

Publikováno v: Blood. 78(4)

Neutrophil research relies largely on studies with highly purified cells. Yet the isolation procedures induce changes in surface expression of several proteins. We used a large panel of monoclonal antibodies (MoAbs) to characterize in detail the phen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e961b482943e27ca741cd7593f4ecc2
https://pubmed.ncbi.nlm.nih.gov/1907873

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Interleukin-6 and interleukin-1 production in acute leukemia with monocytoid differentiation

Autor: CE van der Schoot, P Jansen, M Poorter, MR Wester, AE von dem Borne, LA Aarden, RH van Oers

Publikováno v: Blood. 74:2081-2087

Several authors have reported the in vitro production of colony- stimulating factors (CSF) and interleukin-1 (IL-1) by the neoplastic cells from patients with acute myeloid leukemia (AML). Using a sensitive bioassay for IL-6, the capacity of the leuk

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::98297f1a8d3d4bc8febbb4a855ff421c
https://doi.org/10.1182/blood.v74.6.2081.bloodjournal7462081

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