Zobrazeno 1 - 7
of 7
pro vyhledávání: '"CDNs, cyclic dinucleotides"'
Autor:
Qilong Wang, Yanze Yang, Mei Du, Jinna Wei, Xianxian Zheng, Zhang Han, Erwei Liu, Xiumei Gao, Yuefei Wang, Patrick Kwabena Oduro
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 50-75 (2022)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
The cyclic GMP–AMP synthase (cGAS)–stimulator of interferon genes (STING) signaling exert essential regulatory function in microbial-and onco-immunology through the induction of cytokines, primarily type I interferons. Recently, the aberrant and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eaf60046ceb32698b7a7ea7c3674b44
http://www.sciencedirect.com/science/article/pii/S2211383521001775
http://www.sciencedirect.com/science/article/pii/S2211383521001775
Publikováno v:
JHEP Reports
Summary The recently identified novel cytosolic DNA sensor cyclic GMP-AMP synthase (cGAS) activates the downstream adaptor protein stimulator of interferon genes (STING) by catalysing the synthesis of cyclic GMP-AMP. This in turn initiates an innate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35ff00e7f3f8684bd27542de7a9f4e94
https://pubmed.ncbi.nlm.nih.gov/34381984
https://pubmed.ncbi.nlm.nih.gov/34381984
Publikováno v:
Chinese Journal of Traumatology
Chinese Journal of Traumatology, Vol 25, Iss 1, Pp 1-10 (2022)
Chinese Journal of Traumatology, Vol 25, Iss 1, Pp 1-10 (2022)
Sepsis is a life-threatening clinical syndrome and one of the most challenging health problems in the world. Pathologically, sepsis and septic shock are caused by a dysregulated host immune response to infection, which can eventually lead to multiple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f78f03c1ea030072286a73467e72f2
https://pubmed.ncbi.nlm.nih.gov/34334261
https://pubmed.ncbi.nlm.nih.gov/34334261
Autor:
Eliana M. Coccia, Angela Battistini
Publikováno v:
Seminars in Immunology
Highlights • Type I interferon represents the first line of innate host defense against a number of invading pathogens that also instructs adaptive immunity. • Type I interferon induction downstream germ-line-encoded pattern recognition receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088198a3fa76b174a841b353322ff121
https://doi.org/10.1016/j.smim.2015.03.005
https://doi.org/10.1016/j.smim.2015.03.005
Autor:
Oduro PK; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China., Zheng X; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China., Wei J; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China., Yang Y; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China., Wang Y; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.; State Key Laboratory of Component-Based Chinese Medicine, Ministry of Education, Tianjin 301617, China., Zhang H; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.; State Key Laboratory of Component-Based Chinese Medicine, Ministry of Education, Tianjin 301617, China., Liu E; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.; State Key Laboratory of Component-Based Chinese Medicine, Ministry of Education, Tianjin 301617, China., Gao X; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.; State Key Laboratory of Component-Based Chinese Medicine, Ministry of Education, Tianjin 301617, China., Du M; Department of Pharmacology and Tianjin Key Laboratory of Inflammation Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin 300070, China., Wang Q; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.; State Key Laboratory of Component-Based Chinese Medicine, Ministry of Education, Tianjin 301617, China.
Publikováno v:
Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2022 Jan; Vol. 12 (1), pp. 50-75. Date of Electronic Publication: 2021 May 20.
Autor:
Chen R; Department of Surgery, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China., Du J; College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China., Zhu H; College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China., Ling Q; Department of Surgery, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Publikováno v:
JHEP reports : innovation in hepatology [JHEP Rep] 2021 Jun 24; Vol. 3 (5), pp. 100324. Date of Electronic Publication: 2021 Jun 24 (Print Publication: 2021).
Autor:
Cui J; a Key Laboratory of Gene Engineering of the Ministry of Education; State Key Laboratory of Biocontrol; School of Life Sciences ; Sun Yat-sen University ; Guangzhou , P. R. China., Chen Y, Wang HY, Wang RF
Publikováno v:
Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2014; Vol. 10 (11), pp. 3270-85.