Zobrazeno 1 - 10
of 124
pro vyhledávání: '"CDKN2A Gene"'
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 17, Iss 1, Pp 1-14 (2022)
Abstract Background p16, p53, and proliferating cell nuclear antigen (pcna) genes play significant roles in many chromatin modifications and have been found to be highly expressed in a variety of tumor tissues. Therefore, they have been used as targe
Externí odkaz:
https://doaj.org/article/214568d37594420493083dc5fbe15118
Autor:
Fernando Barbosa, Marco Antônio Oliveira, Henrique César Santejo Silveira, Isana Rodrigues Silva, Cassia Bernardo, Luiza Flavia Veiga Francisco
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Construction workers are exposed to a mixture of substances in the workplace considered carcinogenic. This study aimed to characterise gene-specific changes in DNA methylation over the workweek in this population as this type of environmental exposur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f55831e5c05d1eb342549a78c8aecc7
https://doi.org/10.1080/1354750x.2020.1817981
https://doi.org/10.1080/1354750x.2020.1817981
Autor:
Jaime Eduardo Calonje, Nathan T. Harvey, Carla Thomas, Nima Mesbah Ardakani, Chris van Vliet, Shalinder Singh, Benjamin A. Wood
Publikováno v:
The American Journal of Dermatopathology. 43:182-190
The distinction between nevoid melanoma and a mitotically active nevus can be challenging at the microscopic level. In this study, we performed cytogenetic testing on a cohort of 25 mitotically active melanocytic proliferations resembling common mela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75c4f7530e3a81740258c556f0f17329
https://doi.org/10.1097/dad.0000000000001721
https://doi.org/10.1097/dad.0000000000001721
Akademický článek
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Akademický článek
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Publikováno v:
Cancer Management and Research
Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario
Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario
Asbestos is one of the most important occupational carcinogens. Currently, about 125 million people worldwide are exposed to asbestos in the workplace. According to global estimates, at least 107,000 people die each year from lung cancer, mesotheliom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::3feed2dab074821a1e99c7f9b63cbf6b
http://europepmc.org/articles/PMC6556979
http://europepmc.org/articles/PMC6556979
Publikováno v:
Iranian Journal of Pediatric Hematology & Oncology.
Background: CDKN2A, encoding two important tumor suppressor proteins p16 and p14, is a tumor suppressor gene. Mutations in this gene and subsequently the defect in p16 and p14 proteins lead to the downregulation of RB1/p53 and cancer malignancy. To i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e456b89bf9f91c84456b91107942ad2
https://doi.org/10.18502/ijpho.v11i2.5844
https://doi.org/10.18502/ijpho.v11i2.5844
Autor:
Frida Appelqvist, Veronica Höiom, Teo Helkkula, Maria Pissa, Jenny Pettersson, Kari Nielsen, Åke Borg, Jan Lapins, Hildur Helgadottir, Gustav Silander
Background: Inherited pathogenic variants (PVs) in the CDKN2A gene are among the strongest known risk factors for cutaneous melanoma. Carriers are at high risks to develop multiple primary melanomas and other cancers, in particular pancreatic cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bddb085e0f88515d1b94983d0428d39
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-183591
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-183591
Akademický článek
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Publikováno v:
Cancer Biomarkers. 20:477-485
Testing carcinogenicity caused by chemicals requires a noninvasive tool that can be used before autopsy because autopsy takes a long time. We investigated whether non-small cell lung cancer related gene mutations could be detected in cell-free DNA in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d65d354c11426512b3e7af388d255675
https://doi.org/10.3233/cbm-170303
https://doi.org/10.3233/cbm-170303