Evaluation of P21 waf expression and CDKN1A exon 2 mutation in salivary adenoid cystic carcinoma

Autor: N. Taghavi, Z. Yadegari, F. Yazdani, F. Mashhadiabbas, A. Akbarzadeh Baghban, S. Vafadar

Publikováno v: World Cancer Research Journal, Vol 6 (2019)

Objective: The P21waf is a tumor-suppressor protein encoded by CDKN1A gene. In this study, we evaluated P21waf expression and CDKN1A exon 2 mutation and their relationships with clinicopathological parameters and cancer development in salivary adenoi

Externí odkaz: https://doaj.org/article/fe597bab2c3041569a298851878aa72a

Cyclin D1 and p21 gene variants and oral squamous cell carcinoma risk and prognosis

Autor: Gordana Supic, Ruzica Kozomara, Katarina Zeljic, Debora Stefik, Stosić S, Sasa Jovic, Nemanja Ivkovic

Publikováno v: Archives of Biological Sciences, Vol 73, Iss 4, Pp 437-445 (2021)

Cyclin-dependent kinase inhibitor p21 (encoded by the CDKN1A gene) and cyclin D1 (encoded by the CCND1 gene) are important regulators of cell cycle progression and could have important effects in the complex process of neoplastic transformation. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbc953b2a6f5233fd8872d8a548148d7
https://doi.org/10.2298/abs210813037j

CDKN1A Gene Expression in Two Multiple Myeloma Cell Lines With Different P53 Functionality

Autor: Zdenek Kolar, Denisa Hrckova Drozdkova, Jiri Minarik, Katerina Smesny Trtkova, Ivo Uberall, Jan Gursky

Publikováno v: Anticancer Research. 40:4979-4987

Background/aim Multiple myeloma is a highly heterogeneous disease of clonal plasma cells. Histone deacetylase (HDAC) inhibitors are promising anticancer drugs but their precise mechanisms of actions are not well understood. Materials and methods Cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6eb3272f3b9ec4824eb07db2a2babe86
https://doi.org/10.21873/anticanres.14501

Radiation induces submandibular gland damage by affecting Cdkn1a expression and regulating expression of miR-486a-3p in a xerostomia mouse model

Autor: Xia Dongqin, Xiao Caizhi, Li Fangfei, Chen Hong, Wang Wei

Publikováno v: Advances in clinical and experimental medicine : official organ Wroclaw Medical University. 30(9)

BACKGROUND Radiotherapy has been proven to be an effective treatment strategy for inhibiting head-and-neck cancer. However, side effects are common when using high-dosage irradiation, and the mechanism of action of this therapy has not been fully cla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca565421e815aab59ec9458298be1dbd
https://pubmed.ncbi.nlm.nih.gov/34498815

Proto-Oncogenes and Cell Cycle Gene Expression in Normal and Neoplastic Oral Epithelial Cells Stimulated With Soluble Factors From Single and Dual Biofilms of Candida albicans and Staphylococcus aureus

Autor: María Isabel Amaya Arbeláez, Ana Carolina Alves de Paula e Silva, Geovana Navegante, Valeria Valente, Paula Aboud Barbugli, Carlos Eduardo Vergani

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

Made available in DSpace on 2021-06-25T10:55:14Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-02-25 This study was aimed at analyzing proto-oncogenic signaling pathway activation in normal oral keratinocytes (NOK-si) and neoplastic cell line

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2952eec77c8e94deeaa2b662fc7d9bbc
https://www.frontiersin.org/articles/10.3389/fcimb.2021.627043/full