Zobrazeno 1 - 10
of 138
pro vyhledávání: '"CDK11"'
Autor:
Dalibor Blazek
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 3, Pp n/a-n/a (2023)
Human cyclin‐dependent kinases (CDKs) direct the progression of the cell cycle and transcription. They are deregulated in tumours, and despite their involvement in the regulation of basic cellular processes, many CDKs are promising targets for canc
Externí odkaz:
https://doaj.org/article/53d7107c041044a298ec86ca6d05c615
Autor:
Fatma Al-Mulhim, Amany I. Alqosaibi, Afnan Al-Muhnna, Khalid Farid, Shaimaa Abdel-Ghany, Hamdy Rizk, Abdel-Bary Prince, Adaugo Isichei, Hussein Sabit
Publikováno v:
Electronic Journal of Biotechnology, Vol 53, Iss , Pp 54-60 (2021)
Background: Cancer is a life-threatening disease that affects approximately 18 million individuals worldwide. Breast cancer is the most common female neoplasm globally with more than 276,480 new cases of invasive breast cancer expected to be diagnose
Externí odkaz:
https://doaj.org/article/8f9e91a618d84bb990f2dafb24f9445f
Autor:
Danmin Ou, Lin Chen, Jiang He, Zhuoxian Rong, Jie Gao, Zhi Li, Liyu Liu, Feiyu Tang, Jiang Li, Yuezhen Deng, Lunquan Sun
Publikováno v:
Cancer Biology & Medicine, Vol 17, Iss 2, Pp 328-342 (2020)
Objectives: Improper activation of Wnt/β-catenin signaling has been implicated in human diseases. Beyond the well-studied glycogen synthase kinase 3β (GSK3β) and casein kinase 1 (CK1), other kinases affecting Wnt/β-catenin signaling remain to be
Externí odkaz:
https://doaj.org/article/55b55e68469043c5af7603ae534bdc7e
Autor:
Yong Feng, Yunfei Liao, Jianming Zhang, Jacson Shen, Zengwu Shao, Francis Hornicek, Zhenfeng Duan
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-14 (2019)
Abstract Background Aberrant expression of cyclin-dependent protein kinases (CDK) is a hallmark of cancer. CDK11 plays a crucial role in cancer cell growth and proliferation. However, the molecular mechanisms of CDK11 and CDK11 transcriptionally regu
Externí odkaz:
https://doaj.org/article/db777ab66db24f159fd85eb18155c503
Autor:
Ester Sala, Celia Vived, Júlia Luna, Noemí Alejandra Saavedra-Ávila, Upasana Sengupta, A. Raúl Castaño, Sabrina Villar-Pazos, Laura Haba, Joan Verdaguer, Ana B. Ropero, Thomas Stratmann, Javier Pizarro, Manuel Vázquez-Carrera, Angel Nadal, Jill M. Lahti, Conchi Mora
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundPancreatic islets are exposed to strong pro-apoptotic stimuli: inflammation and hyperglycemia, during the progression of the autoimmune diabetes (T1D). We found that the Cdk11(Cyclin Dependent Kinase 11) is downregulated by inflammation in
Externí odkaz:
https://doaj.org/article/43d700c8d29a47dc8cba0c3b8b15aa2f
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Adaugo C Isichei, Afnan Al-Muhnna, Amany I. Alqosaibi, Hamdy Rizk, Abdelbary Prince, Shaimaa Abdel-Ghany, Khalid Farid, Fatma Al-Mulhim, Hussein Sabit
Publikováno v:
Electronic Journal of Biotechnology, Vol 53, Iss, Pp 54-60 (2021)
Background: Cancer is a life-threatening disease that affects approximately 18 million individuals worldwide. Breast cancer is the most common female neoplasm globally with more than 276,480 new cases of invasive breast cancer expected to be diagnose
Publikováno v:
Journal of International Society of Preventive & Community Dentistry
Objective: This study aimed at evaluating the in vitro effect of Porphyromonas gingivalis exposure in gene expression of E2F1 (family of transcription factors), cyclin-dependent kinase-1 (CDK11), and inducible nitric oxide synthase (iNOS) of the neur