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pro vyhledávání: '"CDK1 (cyclin-dependent kinase 1)"'
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Autor:
Sun, Guoxin
The cardiomyocytes of zebrafish can regenerate in case of necrosis. Several studies have shown that the Bone morphogenetic signaling pathway (BMP signaling) is involved in the process of zebrafish heart regeneration. To identify candidate mediators o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a331e9bcc01454ee31fae970abab1d4
Autor:
Jonsson, Marte, Fjeldbo, Christina Sæten, Holm, Ruth, Stokke, Trond, Kristensen, Gunnar Balle, Lyng, Heidi
Publikováno v:
Neoplasia (New York, N.Y.)
CDK regulatory subunit 2 (CKS2) has a nuclear function that promotes cell division and is a candidate biomarker of chemoradioresistance in cervical cancer. The underlying mechanisms are, however, not completely understood. We investigated whether CKS
Autor:
Xingxing Yang, Vitalii Zablotskii, Biao Yu, Chao Song, Xin Zhang, Junjun Wang, Xin Yu, Lei Zhang
Publikováno v:
Translational Oncology, Vol 14, Iss 7, Pp 101103-(2021)
Translational Oncology
Translational Oncology
Highlights • Upward 9.4 T SMF exposure for 88 h significantly inhibited A549 tumor growth in mice. • 9.4 T SMF treatment for 88 h had no severe impairment to the mice key organs or blood cell count. • Upward 9.4 T SMF treatment for 24 h caused
Publikováno v:
Matrix Biology Plus
Matrix Biology Plus, Vol 12, Iss, Pp 100088-(2021)
Matrix Biology Plus, Vol 12, Iss, Pp 100088-(2021)
Highlights • Runx2 loss in hypertrophic chondrocytes (Runx2HC/HC) causes limb dwarfism in mice. • Decreased apoptosis leads to doubling of the zone of hypertrophic chondrocytes. • Runx2HC/HC hypertrophic chondrocytes barely expresses Mmps and a
Autor:
Ergun Pinarbasi, Merve Nur Aydemir, Mahir Budak, Nilgun Cekin, Ertan Mahir Korkmaz, Habes Bilal Aydemir
Publikováno v:
Gene Reports
Recently an outbreak that emerged in Wuhan, China in December 2019, spread to the whole world in a short time and killed >1,410,000 people. It was determined that a new type of beta coronavirus called severe acute respiratory disease coronavirus type
Autor:
Jianan Sun, Bo Wu, Dahong Li, Hui-Ming Hua, Bao Ji, Shanshan Luo, Fanxing Xu, Yan Xiao, Peng Wang, Chao Zheng, Keguang Cheng, Xu Hu
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 5, Pp 1148-1157 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 5, Pp 1148-1157 (2021)
As one of the most lethal diseases, pancreatic cancer shows a dismal overall prognosis and high resistance to most treatment modalities. Furthermore, pancreatic cancer escapes early detection during the curable period because early symptoms rarely em
Autor:
Satheeswaran Balasubramanian, Ekambaram Perumal, Vignesh Jeyamanickavel Mathan, Kanmani Gunasekaran, Saranyadevi Sasidharan
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 7, Iss, Pp 583-595 (2020)
Toxicology Reports, Vol 7, Iss, Pp 583-595 (2020)
Graphical abstract
Highlights • miRNAs are key regulators of gene expression at both transcription and translation. • The role of miRNAs in xenobiotic toxicity and its potential as biomarkers are being explored. • In spite of numerous stud
Highlights • miRNAs are key regulators of gene expression at both transcription and translation. • The role of miRNAs in xenobiotic toxicity and its potential as biomarkers are being explored. • In spite of numerous stud
Autor:
Richard I. Odle, Simon J. Cook
Publikováno v:
Autophagy
For the last two decades there has been wide ranging debate about the status of macroautophagy during mitosis. Because metazoan cells undergo an “open” mitosis in which the nuclear envelope breaks down, it has been proposed that macroautophagy mu
Autor:
Huifang Xu, Angela Paul, Leo S. Payne, Scott Gridley, Edward A. Esposito, Maciej T. Luczynski, Paul H. Huang, Francis Chang, Birgit Leitinger, Ryan W. Clinton, Leo Kei Iwai, Kristen M. Naegle
Publikováno v:
Biochemical Journal
Collagen is an important extracellular matrix component that directs many fundamental cellular processes including differentiation, proliferation and motility. The signalling networks driving these processes are propagated by collagen receptors such