Zobrazeno 1 - 10
of 204
pro vyhledávání: '"CDK (Cyclin-dependent Kinase)"'
Publikováno v:
Frontiers in Nephrology, Vol 4 (2024)
Various classes of targeted therapies have emerged in the last few years, which have revolutionized cancer treatment, and improved the prognosis and survival of cancer patients. Unfortunately, these agents have serious toxic effects on the kidneys. S
Externí odkaz:
https://doaj.org/article/3582cffd8c884db7974805c719678ef2
Autor:
Sanjay Singh Rawat, Ashverya Laxmi
Publikováno v:
Frontiers in Plant Science, Vol 15 (2024)
Cell cycle involves the sequential and reiterative progression of important events leading to cell division. Progression through a specific phase of the cell cycle is under the control of various factors. Since the cell cycle in multicellular eukaryo
Externí odkaz:
https://doaj.org/article/6c104df25c154ed2a68564c5f5ccb58f
Autor:
Ying Huang, Bin Wang, Faten Hassounah, S. Russ Price, Janet Klein, Tamer M.A. Mohamed, Yanhua Wang, Jeanie Park, Hui Cai, Xuemei Zhang, Xiaonan H. Wang
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 1, Pp 126-141 (2023)
Abstract Background Muscle wasting is a common complication of chronic kidney disease (CKD) that is associated with higher mortality. Although the mechanisms of myofibre loss in CKD has been widely studied, the contribution of muscle precursor cell (
Externí odkaz:
https://doaj.org/article/5327ce09ea9242c2af18493a95b47f85
Autor:
Rachel L. Y. Wong, Megan R. E. Wong, Chik Hong Kuick, Seyed Ehsan Saffari, Meng Kang Wong, Sheng Hui Tan, Khurshid Merchant, Kenneth T. E. Chang, Matan Thangavelu, Giridharan Periyasamy, Zhi Xiong Chen, Prasad Iyer, Enrica E. K. Tan, Shui Yen Soh, N. Gopalakrishna Iyer, Qiao Fan, Amos H. P. Loh
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Neuroblastoma is the commonest extracranial pediatric malignancy. With few recurrent single nucleotide variations (SNVs), mutation-based precision oncology approaches have limited utility, but its frequent and heterogenous copy number variations (CNV
Externí odkaz:
https://doaj.org/article/c94105f2a340474b8a92a8bcd7d1fcc0
Akademický článek
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Akademický článek
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Autor:
David A. Frank, Isidora Tošić
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 12, Pp 1167-1178 (2021)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 12, Pp 1167-1178 (2021)
The oncogenic transcription factor signal transducer and activator of transcription 3 (STAT3) is activated constitutively in a wide array of human cancers. It is an appealing molecular target for novel therapy as it directly regulates expression of g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95fc1e221705a2edcb47149735290583
http://europepmc.org/articles/PMC8569436
http://europepmc.org/articles/PMC8569436
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 2, Pp 340-354 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 2, Pp 340-354 (2021)
Enormous studies have corroborated that long non-coding RNAs (lncRNAs) extensively participate in crucial physiological processes such as metabolism and immunity, and are closely related to the occurrence and development of tumors, cardiovascular dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1331163087be50317f3485f73580768
https://doi.org/10.1016/j.apsb.2020.10.001
https://doi.org/10.1016/j.apsb.2020.10.001
Akademický článek
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Autor:
Sabine Matou-Nasri, Hala Alajmi, Safia A. Messaoudi, Anuradha Venktraman, Zeyad Alehaideb, Mohammed Syed Ali, Saranya Rameshbabu, Hamad Al-Eidi
Publikováno v:
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal, Vol 28, Iss 8, Pp 985-993 (2020)
Saudi Pharmaceutical Journal, Vol 28, Iss 8, Pp 985-993 (2020)
Breast cancer therapy using anticancer bioactive compounds derived from natural products as adjuvant treatment has gained recognition due to expensive and toxic conventional chemotherapeutic drugs. The whole plant of Anastatica hierochuntica (L.) (A.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b4d9d6a94d75e0608ed29d7ae56ebd0
https://doi.org/10.1016/j.jsps.2020.06.020
https://doi.org/10.1016/j.jsps.2020.06.020