Zobrazeno 1 - 10
of 68
pro vyhledávání: '"CDHR3"'
Autor:
Monty E. Goldstein, Maxinne A. Ignacio, Jeffrey M. Loube, Matthew R. Whorton, Margaret A. Scull
Publikováno v:
Viruses, Vol 16, Iss 8, p 1282 (2024)
Rhinovirus C (RV-C) infects airway epithelial cells and is an important cause of acute respiratory disease in humans. To interrogate the mechanisms of RV-C-mediated disease, animal models are essential. Towards this, RV-C infection was recently repor
Externí odkaz:
https://doaj.org/article/03cfa3f44b634fafa597432eba8ed483
Autor:
Yu P. Song, Man F. Tang, Agnes S. Y. Leung, Kin P. Tao, Oi M. Chan, Gary W. K. Wong, Paul K. S. Chan, Renee W. Y. Chan, Ting F. Leung
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 5 (2023)
ABSTRACT Rhinovirus (RV) is the leading pathogen causing childhood wheezing, with rhinovirus C (RV-C) species reported to cause asthma exacerbation. Allele A of single-nucleotide polymorphism (SNP) CDHR3_rs6967330 upregulates epithelial expression of
Externí odkaz:
https://doaj.org/article/cae431285db24543beb675014e19063d
Akademický článek
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Publikováno v:
BMC Pulmonary Medicine, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background As a main line of defense of the respiratory tract, the airway epithelium plays an important role in the pathogenesis of asthma. CDHR3 and EMSY were reported to be expressed in the human airway epithelium. Although previous genome
Externí odkaz:
https://doaj.org/article/92609cedb52f4920bc7f5a36bc2e32be
Publikováno v:
Di-san junyi daxue xuebao, Vol 41, Iss 4, Pp 371-375 (2019)
Objective To explore the association of single nucleotide polymorphism (SNP) at rs6967330 of cadherin-associated family member 3 (CDHR3) gene with acute respiratory tract infection caused by human rhinoviruses (HRVs) in children. Methods From January
Externí odkaz:
https://doaj.org/article/62c61976a1cd4327844a2c9ed630d60e
Autor:
Jun Kanazawa, Hironori Masuko, Yohei Yatagai, Tohru Sakamoto, Hideyasu Yamada, Yoshiko Kaneko, Haruna Kitazawa, Hiroaki Iijima, Takashi Naito, Takefumi Saito, Emiko Noguchi, Satoshi Konno, Masaharu Nishimura, Tomomitsu Hirota, Mayumi Tamari, Nobuyuki Hizawa
Publikováno v:
Allergology International, Vol 66, Iss 4, Pp 563-567 (2017)
Background: Recent studies have demonstrated that a coding SNP (rs6967330, Cys529→Tyr) in cadherin-related family member 3 (CDHR3), which was previously associated with wheezing illness and hospitalizations in infancy, could support efficient human
Externí odkaz:
https://doaj.org/article/254d1cb831744db0b3f2ee5c4232bb59
Autor:
Theodor F. Griggs, Yury A. Bochkov, Sarmila Basnet, Thomas R. Pasic, Rebecca A. Brockman-Schneider, Ann C. Palmenberg, James E. Gern
Publikováno v:
Respiratory Research, Vol 18, Iss 1, Pp 1-11 (2017)
Abstract Background The Rhinovirus C (RV-C), first identified in 2006, produce high symptom burdens in children and asthmatics, however, their primary target host cell in the airways remains unknown. Our primary hypotheses were that RV-C target cilia
Externí odkaz:
https://doaj.org/article/93106c2d94fc4ee6ad472ec327b259c6
Akademický článek
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Publikováno v:
Viruses, Vol 13, Iss 2, p 159 (2021)
Cadherin Related Family Member 3 (CDHR3) is the identified and required cellular receptor for all virus isolates in the rhinovirus-C species (RV-C). Cryo-EM determinations recently resolved the atomic structure of RV-C15a, and subsequently, a complex
Externí odkaz:
https://doaj.org/article/8431a586fa374a849275d2de1f61e327
Autor:
Bochkov, Yury A., Watters, Kelly, Ashraf, Shamaila, Griggs, Theodor F., Devries, Mark K., Jackson, Daniel J., Palmenberg, Ann C., Gern, James E.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2015 Apr . 112(17), 5485-5490.
Externí odkaz:
https://www.jstor.org/stable/26462584