Expression of programmed death ligand 1 in drug-resistant osteosarcoma: An exploratory study

Autor: Fei Chu, Nicholas J. Skertich, Jeffrey A. Borgia, Imad Tarhoni, Stephen Szajek, Mary Beth Madonna

Publikováno v: Surgery Open Science, Vol 6, Iss, Pp 10-14 (2021)
Surgery Open Science

Background: Inhibition of the programmed death ligand 1, programmed death 1 pathway has been successfully used for treatment of multiple advanced adult cancers. However, its use in pediatric osteosarcoma is still in its infancy. In this study, we inv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f4b311880ebd1fc0b8ba946d799acef
http://www.sciencedirect.com/science/article/pii/S2589845021000129

Natural products as LSD1 inhibitors for cancer therapy

Autor: Xiaochuan Li, Chao Yang, Yuan Fang, Guochao Liao, Bin Yu, Qingchun Mu, Zhiqiang Yu

Publikováno v: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 621-631 (2021)
Acta Pharmaceutica Sinica B

Natural products generally fall into the biologically relevant chemical space and always possess novel biological activities, thus making them a rich source of lead compounds for new drug discovery. With the recent technological advances, natural pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee67172081a717a9c2539e0b3e363442
https://pubmed.ncbi.nlm.nih.gov/32837872

Barrier-penetrating liposome targeted delivery of basic fibroblast growth factor for spinal cord injury repair.

Autor: Wu F; Department of Arthroplasty, The First People's Hospital of Wenling, Affiliated Wenling Hospital, Wenzhou Medical University, Zhejiang, 317500, China.; Translational Medicine Laboratory, Affiliated Cixi Hospital, Wenzhou Medical University, Zhejiang, 325300, China.; School of Pharmaceutical Sciences, Wenzhou Medical University, Zhejiang, 325035, China., Wang P; Translational Medicine Laboratory, Affiliated Cixi Hospital, Wenzhou Medical University, Zhejiang, 325300, China., Wei X; Translational Medicine Laboratory, Affiliated Cixi Hospital, Wenzhou Medical University, Zhejiang, 325300, China., Yang Y; School of Pharmaceutical Sciences, Wenzhou Medical University, Zhejiang, 325035, China., Al Mamun A; School of Pharmaceutical Sciences, Wenzhou Medical University, Zhejiang, 325035, China., Zhang X; Department of Pharmacy, Ningbo Medical Treatment Center Li Huili Hospital, Zhejiang, 315040, China., Zhu Y; Department of Arthroplasty, The First People's Hospital of Wenling, Affiliated Wenling Hospital, Wenzhou Medical University, Zhejiang, 317500, China., Mo T; Department of Arthroplasty, The First People's Hospital of Wenling, Affiliated Wenling Hospital, Wenzhou Medical University, Zhejiang, 317500, China., Zhang H; Department of Arthroplasty, The First People's Hospital of Wenling, Affiliated Wenling Hospital, Wenzhou Medical University, Zhejiang, 317500, China.; Translational Medicine Laboratory, Affiliated Cixi Hospital, Wenzhou Medical University, Zhejiang, 325300, China.; School of Pharmaceutical Sciences, Wenzhou Medical University, Zhejiang, 325035, China., Jiang C; Department of Arthroplasty, The First People's Hospital of Wenling, Affiliated Wenling Hospital, Wenzhou Medical University, Zhejiang, 317500, China., Hu J; Stem Cell Translation Laboratory, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Shanxi, 030032, China., Xiao J; Department of Arthroplasty, The First People's Hospital of Wenling, Affiliated Wenling Hospital, Wenzhou Medical University, Zhejiang, 317500, China.; Translational Medicine Laboratory, Affiliated Cixi Hospital, Wenzhou Medical University, Zhejiang, 325300, China.; School of Pharmaceutical Sciences, Wenzhou Medical University, Zhejiang, 325035, China.

Publikováno v: Materials today. Bio [Mater Today Bio] 2023 Jan 07; Vol. 18, pp. 100546. Date of Electronic Publication: 2023 Jan 07 (Print Publication: 2023).

Targeting hydrogen sulphide signaling in breast cancer.

Autor: Youness RA; Department of Pharmaceutical Biology, Faculty of Pharmacy and Biotechnology, German University in Cairo, Egypt., Gad AZ; Interdepartmental Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, Houston, TX 77030, USA.; Center for Cell and Gene Therapy, Texas Children's Hospital, Houston Methodist Hospital, Baylor College of Medicine, Houston, TX 77030, USA.; Texas Children's Cancer and Hematology Centers, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA., Sanber K; Center for Cell and Gene Therapy, Texas Children's Hospital, Houston Methodist Hospital, Baylor College of Medicine, Houston, TX 77030, USA.; Texas Children's Cancer and Hematology Centers, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA., Ahn YJ; Department of Medical Engineering, Graduate School, Kyung Hee University, Seoul 130-701, Republic of Korea.; Department of Biomedical Engineering, College of Medicine, Kyung Hee University, Seoul 130-701, Republic of Korea., Lee GJ; Department of Medical Engineering, Graduate School, Kyung Hee University, Seoul 130-701, Republic of Korea.; Department of Biomedical Engineering, College of Medicine, Kyung Hee University, Seoul 130-701, Republic of Korea., Khallaf E; Department of General Surgery, Faculty of Medicine, Cairo University, 12613 Cairo, Egypt., Hafez HM; Department of General Surgery, Faculty of Medicine, Cairo University, 12613 Cairo, Egypt., Motaal AA; Department of Pharmacognosy, College of Pharmacy, King Khalid University, Abha, Saudi Arabia.; Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Egypt., Ahmed N; Interdepartmental Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, Houston, TX 77030, USA.; Center for Cell and Gene Therapy, Texas Children's Hospital, Houston Methodist Hospital, Baylor College of Medicine, Houston, TX 77030, USA.; Texas Children's Cancer and Hematology Centers, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030, USA., Gad MZ; Department of Biochemistry, Faculty of Pharmacy and Biotechnology, German University in Cairo, Egypt.

Publikováno v: Journal of advanced research [J Adv Res] 2020 Jul 16; Vol. 27, pp. 177-190. Date of Electronic Publication: 2020 Jul 16 (Print Publication: 2021).