Zobrazeno 1 - 10
of 1 599
pro vyhledávání: '"CD8 T lymphocytes"'
Autor:
Wenchang Zhou, Mengdi Qu, Ying Yue, Ziwen Zhong, Ke Nan, Xingfeng Sun, Qichao Wu, Jie Zhang, Wankun Chen, Changhong Miao
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Programmed cell death protein 1 (PD-1) blockade is essential in treating progressive colorectal cancer (CRC). However, some patients with CRC do not respond well to immunotherapy, possibly due to the exhaustion of CD8+ T cells in
Externí odkaz:
https://doaj.org/article/08cae4454219400b8c151d78ebbc6de4
Autor:
Fanhai LI, Xiaowen CHEN, Linfeng ZHOU, Jieting HUANG, Xiaofan LI, Bi ZHONG, Mei XIAO, Huaqin LIANG
Publikováno v:
Zhongguo shuxue zazhi, Vol 37, Iss 9, Pp 1058-1062 (2024)
Objective To explore the effectiveness of using donor plasma reinfusion to flush the leukoreduction system (LRS) chamber during the final reinfusion phase with the Trima Accel automated blood collection system in preventing the reduction of CD4+ and
Externí odkaz:
https://doaj.org/article/d689e76cbce54e6f8f249581559b457f
Autor:
Álvaro Gómez-Morón, Ilya Tsukalov, Camila Scagnetti, Clara Pertusa, Marta Lozano-Prieto, Pedro Martínez-Fleta, Silvia Requena, Pilar Martín, Aranzazu Alfranca, Enrique Martin-Gayo, Noa B Martin-Cofreces
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/83182ebdf4bf4272a6d2e53e7cabd129
Autor:
Aykut Elicora, Busra Yaprak Bayrak, Cigdem Vural, Huseyin Fatih Sezer, Semra Uzun Erkal, Elif Metin
Publikováno v:
Journal of Cardiothoracic Surgery, Vol 19, Iss 1, Pp 1-12 (2024)
Abstract Objective The basis for current and future lung cancer immunotherapy depends on our knowledge of molecular mechanisms of interactions between tumor and immune system cells. Interactions that occur between different intratumoral populations o
Externí odkaz:
https://doaj.org/article/119fd0dff1ff420089ea6c1dcff8af51
Autor:
Álvaro Gómez-Morón, Ilya Tsukalov, Camila Scagnetti, Clara Pertusa, Marta Lozano-Prieto, Pedro Martínez-Fleta, Silvia Requena, Pilar Martín, Aranzazu Alfranca, Enrique Martin-Gayo, Noa B Martin-Cofreces
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionCD8+ cytotoxic T lymphocytes (CTLs) are highly effective in defending against viral infections and tumours. They are activated through the recognition of peptide–MHC-I complex by the T-cell receptor (TCR) and co-stimulation. This cognat
Externí odkaz:
https://doaj.org/article/0ac181f7f4fc4d9c8e1b085025124003
Autor:
Dimitrios Bouzianas, Stella Bouziana
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 4, Iss 5, Pp 1128-1135 (2023)
On Feb 2, 2022, Nature published the paper titled “Decade-long leukemia remissions with the persistence of CD4+ CAR T-cells” (Nature. 2022;602:503–9. doi: 10.1038/s41586-021-04390-6). According to the results presented, it could be argued that
Externí odkaz:
https://doaj.org/article/48240fb8afa14d599f695bb0f83223d3
Publikováno v:
European Journal of Medical Research, Vol 28, Iss 1, Pp 1-10 (2023)
Abstract Background Acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) are the most common types of leukemia in adults with an overall poor prognosis. PD-1 alone or combined with other immune checkpoint blockade is a promising resear
Externí odkaz:
https://doaj.org/article/99b763588e0a4adc85f0051625e593ce
Autor:
Patricia García Ramírez, Marta Callejas Charavia, Raquel Oliva Martin, Ana María Gómez La Hoz, Miguel Ángel Ortega, Julio García Suárez, Melchor Álvarez-Mon, Jorge Monserrat Sanz
Publikováno v:
Vaccines, Vol 12, Iss 9, p 961 (2024)
Background: Patients with B-lymphocyte malignancies (BCMs) receiving B-lymphocyte-targeted therapies have increased risk of severe COVID-19 outcomes and impaired antibody response to SARS-CoV-2 mRNA vaccination in comparison to non-hematologic oncolo
Externí odkaz:
https://doaj.org/article/2f699127fad34f4b904b6365be6e7e9c
Autor:
Marek Lenárt, Peter Bober, Miroslav Marcin, Soňa Tkáčiková, Mária Kacírová, Michal Alexovič, Dávid Tóth, Natália Madárová, Jozef Radoňak, Peter Urdzík, Ján Fedačko, Ján Sabo
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6423 (2024)
Peripheral blood CD8+ T lymphocytes play a crucial role in cell-mediated immunity and tumor-related immune responses in breast cancer. In this study, label-free quantification analysis and gene set enrichment analysis (GSEA) of CD8+ T lymphocytes in
Externí odkaz:
https://doaj.org/article/41d10b545b774594961b7ae5ec9f9389
Peripheral Blood CD8+ T-Lymphocyte Subsets Are Associated with Prognosis in Prostate Cancer Patients
Autor:
Constantin N. Baxevanis, Savvas Stokidis, Maria Goulielmaki, Angelos D. Gritzapis, Sotirios P. Fortis
Publikováno v:
Onco, Vol 3, Iss 3, Pp 165-174 (2023)
Background: Various studies have reported associations between frequencies of total peripheral blood lymphocytes and prostate cancer prognosis, but none so far has addressed the prognostic role of CD8+ T-lymphocyte subsets. Methods: A total of 43 pro
Externí odkaz:
https://doaj.org/article/de2a9de8d51e4d45a4d6991f43921aa3