Tumor‐Associated Macrophage‐Derived Exosomal LINC01232 Induces the Immune Escape in Glioma by Decreasing Surface MHC‐I Expression

Autor: Junjun Li, Keshan Wang, Chao Yang, Kai Zhu, Cheng Jiang, Minjie Wang, Zijie Zhou, Nan Tang, Qiangping Wang, Siqi Wang, Pengwei Shu, Hongliang Yuan, Zhiyong Xiong, Jinsong Li, Tao Liang, Jin Rao, Xuan Wang, Xiaobing Jiang

Publikováno v: Advanced Science, Vol 10, Iss 17, Pp n/a-n/a (2023)

Abstract Tumor‐associated macrophage (TAM) infiltration facilitates glioma malignancy, but the underlying mechanisms remain unclear. Herein, it is reported that TAMs secrete exosomal LINC01232 to induce tumor immune escape. Mechanistically, LINC012

Externí odkaz: https://doaj.org/article/bb2ea196f5ff435a9db922330bea8186

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CD4(+) and CD8(+) cytotoxic Tlymphocytes may induce mesenchymal cell apoptosis in IgG(4)-related disease

Autor: Yesim Tuncay, Liam Harvey, Akira Tinju, Vinay Mahajan, Hugues Allard-Chamard, Samuel J.H. Murphy, Cory A. Perugino, Jesper Kers, Takashi Maehara, Seiji Nakamura, Ryusuke Munemura, Xiuwei Zhang, Emanuel Della-Torre, Mizuki Sakamoto, Hang Liu, Sydney B. Montesi, Zachary S. Wallace, Musie Ghebremichael, Lloyd L. Liang, Keita Mochizuki, John H. Stone, Geetha H. Mylvaganam, Masafumi Moriyama, Shiv Pillai, Nir Yosef, Naoki Kaneko, Hamid Mattoo, Marcy B. Bolster

Publikováno v: Journal of Allergy and Clinical Immunology, 147(1), 368-382. MOSBY-ELSEVIER
Journal of allergy and clinical immunology, 147(1), 368-382. Mosby Inc.

Background: IgG(4)-related disease (IgG(4)-RD) is an immune-mediated fibrotic disorder that has been linked to CD4(+) cytotoxic T lymphocytes (CD4(+)CTLs). The effector phenotype of CD4(+)CTLs and the relevance of both CD8(+) cytotoxic T lymphocytes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80ef7590afa08540796322d5278b038c
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704943

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Novel CD8+ cytotoxic T cell epitopes in bovine leukemia virus with cattle

Autor: Junko Kohara, Shin-nosuke Takeshima, Yoko Aida, Emiko Isogai, Lanlan Bai

Publikováno v: Vaccine. 33(51):7194-7202

Bovine leukemia virus (BLV) is associated with enzootic bovine leukosis and is closely related to human T cell leukemia virus (HTLV). The cytotoxic T lymphocyte (CTL) plays a key role in suppressing the progression of disease caused by BLV. T and B c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8afda9e551d6ae4f35d072f5df8105f