Double Positive CD4+CD8+ T Cells Are Enriched in Urological Cancers and Favor T Helper-2 Polarization

Autor: Denise Nardelli-Haefliger, Ilaria Lucca, Massimo Valerio, Patrice Jichlinski, Sonia-Christina Rodrigues-Dias, Laurent Derré, Rodolfo Burruni, Florence Dartiguenave, Thomas Tawadros, Valérie Cesson, Perrine Bohner, Mathieu F. Chevalier

Publikováno v: Frontiers in Immunology
Frontiers in Immunology, Frontiers, 2019, 10, ⟨10.3389/fimmu.2019.00622⟩
Frontiers in Immunology, Vol 10 (2019)
Frontiers in immunology, vol. 10, pp. 622

The immune system plays a central role in cancer development, showing both anti-tumor and pro-tumor activities depending on the immune cell subsets and the disease context. While CD8 T cells are associated with a favorable outcome in most cancers, on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f34716cc65e1b6de45583df3a05f67e
https://hal.archives-ouvertes.fr/hal-03031633/document