Zobrazeno 1 - 10
of 6 958
pro vyhledávání: '"CD8+ T cell"'
Autor:
Yongfeng Wang, Yanzong Zhao, Guangming Zhang, Yifeng Lin, Chunling Fan, Hui Wei, Shude Chen, Ling Guan, Kan Liu, Shenhan Yu, Liangyin Fu, Jing Zhang, Yuan Yuan, Jin He, Hui Cai
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Lymphocyte activating gene-3 (LAG3) is a distinctive T cell co-receptor that is expressed on the surface of lymphocytes. It plays a special inhibitory immune checkpoint role due to its unique domain and signaling pattern. Our aim is to explo
Externí odkaz:
https://doaj.org/article/43912141bdbf44bda946214736fc3bb9
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-10 (2024)
Abstract Background We previously developed a nanobody targeting CTLA-4 and demonstrated that it can boost antitumour T-cell responses in vitro; however, the resulting responses after the injection of T cells into cancer models are usually weak and t
Externí odkaz:
https://doaj.org/article/1d9648289cd04c1d8d03e3f097f821bd
Autor:
Haodi Ma, LinLin Shi, Jiayu Zheng, Li Zeng, Youyou Chen, Shunshun Zhang, Siya Tang, Zhifeng Qu, Xin Xiong, Xuewei Zheng, Qinan Yin
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Background Breast cancer (BC) is the most common cancer in women and poses a significant health burden, especially in China. Despite advances in diagnosis and treatment, patient variability and limited early detection contribute to poor outc
Externí odkaz:
https://doaj.org/article/dcb219362b4648eab7a7e7c15a6987ae
Autor:
Zhouchi Yao, Yayun Zeng, Cheng Liu, Huimin Jin, Hong Wang, Yue Zhang, Chengming Ding, Guodong Chen, Daichao Wu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-30 (2024)
Abstract Vigorous CD8+ T cells play a crucial role in recognizing tumor cells and combating solid tumors. How T cells efficiently recognize and target tumor antigens, and how they maintain the activity in the “rejection” of solid tumor microenvir
Externí odkaz:
https://doaj.org/article/c159f7deadc24d5cbcbfdeed7b8a2bc0
Autor:
Bingyu Wang, Wenbo Liu, Mingming Zhang, Yong Li, Hongyue Tang, Yingying Wang, Chao Song, Buyun Song, Bibo Tan
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background While small extracellular vesicles (sEVs)-derived circular RNAs (circRNAs) have been emerged as significant players in cancer, the function and underlying mechanism of sEVs-derived circRNAs in anti-cancer immunity remain unclear.
Externí odkaz:
https://doaj.org/article/d46d700692fd433ea7adddbd38bae2c3
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-14 (2024)
Abstract Tuberculosis is a serious global health burden, resulting in millions of deaths each year. Several circulating cell subsets in the peripheral blood are known to modulate the host immune response to Mycobacterium tuberculosis (Mtb) infection
Externí odkaz:
https://doaj.org/article/8cc4cfcce60b46dfa802e649c3ccf907
Autor:
Chang Yan, Guohai Yang, Chaojun Zhang, KaiHua Chen, Yongchu Sun, Zhongguo Liang, Lin Lai, Ling Li, Song Qu, Xiao-Dong Zhu
Publikováno v:
Radiation Oncology, Vol 19, Iss 1, Pp 1-12 (2024)
Abstract Purpose To explore the influence of circulating lymphocyte subsets, serum markers, clinical factors, and their impact on overall survival (OS) in locally advanced nasopharyngeal carcinoma (LA-NPC). Additionally, to construct a nomogram predi
Externí odkaz:
https://doaj.org/article/f0c93b9d54fb447b9f232f686592c6ef
Autor:
Haiyan Dong, Chuangyu Wen, Lu He, Jingdan Zhang, Nanlin Xiang, Liumei Liang, Limei Hu, Weiqian Li, Jiaqi Liu, Mengchen Shi, Yijia Hu, Siyu Chen, Huanliang Liu, Xiangling Yang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Although immune checkpoint inhibitors (ICIs) have revolutionized the landscape of cancer treatment, only a minority of colorectal cancer (CRC) patients respond to them. Enhancing tumor immunogenicity by increasing major histocompa
Externí odkaz:
https://doaj.org/article/a1c66e2cc6294c2fb176311e2e439867
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 8, Pp 3780-3782 (2024)
Externí odkaz:
https://doaj.org/article/386b9bc9ee8b4ace93403357dc832e7d
Autor:
Wuyi Liu, Huyue Zhou, Wenjing Lai, Changpeng Hu, Qiaoling Wang, Chengsha Yuan, Chunmei Luo, Mengmeng Yang, Min Hu, Rong Zhang, Guobing Li
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Artesunate (ART), a natural product isolated from traditional Chinese plant Artemisia annua, has not been extensively explored for its anti-melanoma properties. In our study, we found that ART inhibited melanoma cell proliferation and induce
Externí odkaz:
https://doaj.org/article/957fe5ade6f84d5fb258d22286eb1263