Zobrazeno 1 - 10
of 2 846
pro vyhledávání: '"CD74"'
Autor:
Jianghong Cheng, Junyang Li, Xinjie Jiang, Xi Ma, Bixuan Li, Han Zhai, Xianyang Luo, Yi Zhou, Junhua Wu, Zhiming Zhang, Shuai Chen, Yang Wang
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-16 (2024)
Abstract Background CD74 is ectopically expressed in many tumors and can regulate tumor immunity. However, there are many gaps in the study of the prognostic value of CD74 expression and immune infiltration in hepatocellular carcinoma (HCC). Methods
Externí odkaz:
https://doaj.org/article/51510eb3600c4fe6a4562993a068015d
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Background CD74 is a non-polymorphic type II transmembrane glycoprotein. It is involved in the regulation of T and B cell development, and dendritic cell (DC) motility. Numerous studies have found that CD74 exerts an essential role in tumor
Externí odkaz:
https://doaj.org/article/f7f3a3f71abe42aeaebf86d373230f6f
Autor:
Lichao Liu, Jian Wang, Ying Wang, Lingjuan Chen, Ling Peng, Yawen Bin, Peng Ding, Ruiguang Zhang, Fan Tong, Xiaorong Dong
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-20 (2024)
Abstract Background Brain metastasis is one of the main causes of recurrence and death in non-small cell lung cancer (NSCLC). Although radiotherapy is the main local therapy for brain metastasis, it is inevitable that some cancer cells become resista
Externí odkaz:
https://doaj.org/article/836e2093d6fa48c1b229690be5a03dc9
Redox-dependent plasticity of oxMIF facilitates its interaction with CD74 and therapeutic antibodies
Autor:
Sara Sajko, Erin Skeens, Alexander Schinagl, Maroua Ferhat, Irina Mirkina, Julia Mayer, Gregor Rossmueller, Michael Thiele, George P. Lisi
Publikováno v:
Redox Biology, Vol 75, Iss , Pp 103264- (2024)
MIF is a ubiquitous protein involved in proinflammatory processes, which undergoes an oxidation-driven conformational change to oxidized (ox)MIF. We demonstrate that hypochlorous acid, produced by neutrophil-released myeloperoxidase (MPO) under infla
Externí odkaz:
https://doaj.org/article/c6babf44e7bb434a82ae91e78c563cd1
Autor:
Denian Wang, Sixiang Li, Zhi Yang, Chunyan Yu, Pengfei Wu, Ying Yang, Rui Zhang, Qingyan Li, Jian Yang, Hongchun Li, Guiyi Ji, Yan Wang, Kang Xie, Yanyan Liu, Kaige Wang, Daxing Zhu, Wengeng Zhang, Dan Liu, Bojiang Chen, Weimin Li
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 8, Pp n/a-n/a (2024)
Abstract Background Chronic obstructive pulmonary disease (COPD) contributes to the incidence and prognosis of lung cancer. The presence of COPD significantly increases the risk of lung squamous cell carcinoma (LSCC). COPD may promote an immunosuppre
Externí odkaz:
https://doaj.org/article/56aec8f3449d41daa8efa5a7f33de654
Autor:
Ayana Suzuki, Satoshi Nojima, Shinichiro Tahara, Daisuke Motooka, Masaharu Kohara, Daisuke Okuzaki, Mitsuyoshi Hirokawa, Eiichi Morii
Publikováno v:
Journal of Pathology and Translational Medicine, Vol 58, Iss 1, Pp 22-28 (2024)
Background Follicular tumors include follicular thyroid adenomas and carcinomas; however, it is difficult to distinguish between the two when the cytology or biopsy material is obtained from a portion of the tumor. The presence or absence of invasion
Externí odkaz:
https://doaj.org/article/6790e83294cd48d5829aff83284d014b
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Akademický článek
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Single‐cell RNA sequencing reveals inflammatory retinal microglia in experimental autoimmune uveitis
Autor:
Jiangyi Liu, Xingyun Liao, Na Li, Zongren Xu, Wang Yang, Hongxiu Zhou, Yusen Liu, Zhi Zhang, Guoqing Wang, Shengping Hou
Publikováno v:
MedComm, Vol 5, Iss 4, Pp n/a-n/a (2024)
Abstract Autoimmune uveitis (AU) is a kind of immune‐mediated disease resulting in irreversible ocular damage and even permanent vision loss. However, the precise mechanism underlying dynamic immune changes contributing to disease initiation and pr
Externí odkaz:
https://doaj.org/article/950c88ce32a247dba87b0802384468f3
Autor:
Hailang Fan, Lairong Song, Jian Fan, Junpeng Ma, Xiaojie Li, Junting Zhang, Jian Hu, Zhen Wu, Dake Zhang, Liang Wang
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-18 (2023)
Abstract Background Analyzing meningioma of distinct pathological types at the single-cell level can provide new and valuable insights into the specific biological mechanisms of each cellular subpopulation, as well as their vital interplay within the
Externí odkaz:
https://doaj.org/article/47c46504377242f38e964ebe0dd8d5d8