Zobrazeno 1 - 10
of 39
pro vyhledávání: '"CD47-SIRPα ‘don't eat me' signaling"'
Autor:
Peter E. van Bommel, Yuan He, Ilona Schepel, Mark A. J. M. Hendriks, Valerie R. Wiersma, Robert J. van Ginkel, Tom van Meerten, Emanuele Ammatuna, Gerwin Huls, Douwe F. Samplonius, Wijnand Helfrich, Edwin Bremer
Publikováno v:
OncoImmunology, Vol 7, Iss 2 (2018)
Here, we report on a novel bispecific antibody-derivative, designated RTX-CD47, with unique capacity for CD20-directed inhibition of CD47-SIRPα “don't eat me” signaling. RTX-CD47 comprises a CD20-targeting scFv antibody fragment derived from rit
Externí odkaz:
https://doaj.org/article/28534e798d5449938af49fe87651c684
Akademický článek
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Autor:
van Bommel PE; University of Groningen, University Medical Center Groningen (UMCG), Department of Surgery, Laboratory for Translational Surgical Oncology, Groningen, The Netherlands., He Y; University of Groningen, University Medical Center Groningen (UMCG), Department of Hematology, Groningen, The Netherlands., Schepel I; University of Groningen, University Medical Center Groningen (UMCG), Department of Surgery, Laboratory for Translational Surgical Oncology, Groningen, The Netherlands., Hendriks MAJM; University of Groningen, University Medical Center Groningen (UMCG), Department of Surgery, Laboratory for Translational Surgical Oncology, Groningen, The Netherlands., Wiersma VR; University of Groningen, University Medical Center Groningen (UMCG), Department of Surgery, Laboratory for Translational Surgical Oncology, Groningen, The Netherlands., van Ginkel RJ; University of Groningen, University Medical Center Groningen (UMCG), Department of Surgery, Laboratory for Translational Surgical Oncology, Groningen, The Netherlands., van Meerten T; University of Groningen, University Medical Center Groningen (UMCG), Department of Hematology, Groningen, The Netherlands., Ammatuna E; University of Groningen, University Medical Center Groningen (UMCG), Department of Hematology, Groningen, The Netherlands., Huls G; University of Groningen, University Medical Center Groningen (UMCG), Department of Hematology, Groningen, The Netherlands., Samplonius DF; University of Groningen, University Medical Center Groningen (UMCG), Department of Surgery, Laboratory for Translational Surgical Oncology, Groningen, The Netherlands., Helfrich W; University of Groningen, University Medical Center Groningen (UMCG), Department of Surgery, Laboratory for Translational Surgical Oncology, Groningen, The Netherlands., Bremer E; University of Groningen, University Medical Center Groningen (UMCG), Department of Hematology, Groningen, The Netherlands.
Publikováno v:
Oncoimmunology [Oncoimmunology] 2017 Oct 31; Vol. 7 (2), pp. e1386361. Date of Electronic Publication: 2017 Oct 31 (Print Publication: 2018).
Autor:
Gerwin Huls, Mark A. J. M. Hendriks, Yuan He, Tom van Meerten, Valerie R. Wiersma, Wijnand Helfrich, Peter E. van Bommel, Edwin Bremer, Robert J. van Ginkel, Ilona Schepel, Emanuele Ammatuna, Douwe F. Samplonius
Publikováno v:
Oncoimmunology
OncoImmunology, 7(2):e1386361. Taylor & Francis Group
OncoImmunology, Vol 7, Iss 2 (2018)
OncoImmunology, 7(2):e1386361. Taylor & Francis Group
OncoImmunology, Vol 7, Iss 2 (2018)
Here, we report on a novel bispecific antibody-derivative, designated RTX-CD47, with unique capacity for CD20-directed inhibition of CD47-SIRP alpha "don't eat me" signaling. RTX-CD47 comprises a CD20-targeting scFv antibody fragment derived from rit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba8392883f0e254e6011aa63530d61e2
http://europepmc.org/articles/PMC5749665
http://europepmc.org/articles/PMC5749665
Autor:
Ewa Cendrowicz, Lisa Jacob, Shirley Greenwald, Ami Tamir, Iris Pecker, Rinat Tabakman, Lucy Ghantous, Liat Tamir, Roy Kahn, Jasmine Avichzer, Alexandra Aronin, Shira Amsili, Elina Zorde-Khvalevsky, Yosi Gozlan, Martijn Vlaming, Gerwin Huls, Tom van Meerten, Michal Elhalel Dranitzki, Adam Foley-Comer, Yaron Pereg, Amnon Peled, Ayelet Chajut, Edwin Bremer
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-16 (2022)
Abstract Background Treatment of Diffuse Large B Cell Lymphoma (DLBCL) patients with rituximab and the CHOP treatment regimen is associated with frequent intrinsic and acquired resistance. However, treatment with a CD47 monoclonal antibody in combina
Externí odkaz:
https://doaj.org/article/88f427a2882642b7b2f32986f378f0e2
Autor:
Cendrowicz, Ewa1 (AUTHOR), Jacob, Lisa1,2 (AUTHOR), Greenwald, Shirley2 (AUTHOR), Tamir, Ami2 (AUTHOR), Pecker, Iris2 (AUTHOR), Tabakman, Rinat2 (AUTHOR), Ghantous, Lucy3 (AUTHOR), Tamir, Liat2 (AUTHOR), Kahn, Roy2 (AUTHOR), Avichzer, Jasmine2 (AUTHOR), Aronin, Alexandra2 (AUTHOR), Amsili, Shira2 (AUTHOR), Zorde-Khvalevsky, Elina4 (AUTHOR), Gozlan, Yosi2 (AUTHOR), Vlaming, Martijn1 (AUTHOR), Huls, Gerwin1 (AUTHOR), van Meerten, Tom1 (AUTHOR), Dranitzki, Michal Elhalel3 (AUTHOR), Foley-Comer, Adam2 (AUTHOR), Pereg, Yaron2 (AUTHOR)
Publikováno v:
Journal of Experimental & Clinical Cancer Research (17569966). 3/14/2022, Vol. 41 Issue 1, p1-16. 16p.
Publikováno v:
Journal of Hematology & Oncology. 5/6/2024, Vol. 17 Issue 1, p1-7. 7p.
Autor:
Cheng, Jingyun1 (AUTHOR), Huang, Hui2 (AUTHOR) huanghuish@shu.edu.cn, Chen, Yu2,3 (AUTHOR) chenyuedu@shu.edu.cn, Wu, Rong1 (AUTHOR) wurong7111@sjtu.edu.cn
Publikováno v:
Advanced Science. 12/27/2023, Vol. 10 Issue 36, p1-46. 46p.
Publikováno v:
Nano Letters; June 2023, Vol. 23 Issue: 12 p5562-5572, 11p
Autor:
Ploeg, Emily Maria1 (AUTHOR) e.m.ploeg@umcg.nl, Britsch, Isabel1 (AUTHOR), van Wijngaarden, Anne Paulien1 (AUTHOR), Ke, Xiurong1 (AUTHOR), Hendriks, Mark Alexander Johannes Martinus1 (AUTHOR), Samplonius, Douwe Freerk1 (AUTHOR), Helfrich, Wijnand1 (AUTHOR) w.helfrich@umcg.nl
Publikováno v:
Cancers. Jul2023, Vol. 15 Issue 14, p3651. 15p.