Class-modeling analysis reveals T-cell homeostasis disturbances involved in loss of immune control in elite controllers

Autor: José M. Benito, María C. Ortiz, Agathe León, Luis A. Sarabia, José M. Ligos, María Montoya, Marcial Garcia, Ezequiel Ruiz-Mateos, Rosario Palacios, Alfonso Cabello, Clara Restrepo, Carmen Rodriguez, Jorge del Romero, Manuel Leal, María A. Muñoz-Fernández, José Alcamí, Felipe García, Miguel Górgolas, Norma Rallón, On behalf of ECRIS integrated in the Spanish AIDS Research Network

Publikováno v: BMC Medicine, Vol 16, Iss 1, Pp 1-12 (2018)

Abstract Background Despite long-lasting HIV replication control, a significant proportion of elite controller (EC) patients may experience CD4 T-cell loss. Discovering perturbations in immunological parameters could help our understanding of the mec

Externí odkaz: https://doaj.org/article/03d5b5b4d6f8419c8c20967eec6cee93

Class-modeling analysis reveals T-cell homeostasis disturbances involved in loss of immune control in elite controllers

Autor: Benito, José M., Ortiz, María C., León García, Agathe, Sarabia, Luis A., Ligos, José M., Montoya, María, García, Marcial, Ruiz Mateos, Ezequiel, Palacios, Rosario, Cabello, Alfonso, Restrepo, Clara, Rodríguez, Carmen, del Romero, Jorge, Leal, Manuel, Munoz Fernández, María A., Alcamí, José, García Alcaide, Felipe, Górgolas, Miguel, Rallón, Norma, ECRIS integrated in the Spanish AIDS Research Netw

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Repisalud
Instituto de Salud Carlos III (ISCIII)
BMC Medicine
BMC Medicine, Vol 16, Iss 1, Pp 1-12 (2018)
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Repositorio Institucional de la Universidad de Burgos (RIUBU)
instname

Despite long-lasting HIV replication control, a significant proportion of elite controller (EC) patients may experience CD4 T-cell loss. Discovering perturbations in immunological parameters could help our understanding of the mechanisms that may be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::740088dbc9327aede0c74eaf628e9a9c
http://hdl.handle.net/2445/177029

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Simian-Human Immunodeficiency Viruses Expressing Chimeric Subtype B/C Vpu Proteins Demonstrate the Importance of the Amino Terminal and Transmembrane Domains in the Rate of CD4+ T Cell Loss in Macaques

Autor: Nathan Culley, Kimberly Schmitt, Edward B. Stephens, Autumn Ruiz

Previously, we reported that simian-human immunodeficiency viruses expressing either the lab adapted subtype B (SHIV(KU-1bMC33)) or subtype C (SHIV(SCVpu)) Vpu proteins of human immunodeficiency virus type 1 (HIV-1) had different rates of CD4(+) T ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b50a97b994e6ddd47e1cdecc100ba085
https://europepmc.org/articles/PMC4104993/