Zobrazeno 1 - 10
of 2 400
pro vyhledávání: '"CD39"'
Autor:
Carla Fernanda Furtado Gardani, Fernando Mendonça Diz, Luísa Brandalise Dondé, Liliana Rockenbach, Stefan Laufer, Fernanda Bueno Morrone
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Purines and pyrimidines are signaling molecules in the tumor microenvironment that affect cancer immunity. The purinergic signaling pathways have been shown to play an important role in the development and progression of cancer. CD39 and CD73 are ect
Externí odkaz:
https://doaj.org/article/a212efaf8ba745b8ad62c31a4f892f44
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 178, Iss , Pp 117285- (2024)
The review article titled CD39 Transforming Cancer Therapy by Modulating Tumor Microenvironment published in June 2024 in Cancer Letters provides a comprehensive overview of CD39's multifaceted roles in cancer, particularly its influence on immunoreg
Externí odkaz:
https://doaj.org/article/966521bcf7f549ccbc06a73566642044
Autor:
Ornella Franzese, Belinda Palermo, Giuseppe Frisullo, Mariangela Panetta, Giulia Campo, Daniel D’Andrea, Isabella Sperduti, Riccardo Taje, Paolo Visca, Paola Nisticò
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Improving cancer immunotherapy efficacy hinges on identifying key T-cell populations critical for tumor control and response to Immune Checkpoint Blockade (ICB). We have recently reported that while the co-expression of PD-1 and CD28 is associated wi
Externí odkaz:
https://doaj.org/article/4a3fe000f0ec40e5ac1a176751a5d0fd
Autor:
Marius Witt, Leticia Oliveira-Ferrer, Friedrich Koch-Nolte, Stephan Menzel, Louisa Hell, Tabea Sturmheit, Elisa Seubert, Pauline Weimer, Yi Ding, Minyue Qi, Barbara Schmalfeldt, Carsten Bokemeyer, Walter Fiedler, Jasmin Wellbrock, Franziska Brauneck
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Immune exhaustion is a hallmark of ovarian cancer. Using multiparametric flow cytometry, the study aimed to analyze protein expression of novel immunological targets on CD3+ T cells isolated from the peripheral blood (n = 20), malignant ascites (n =
Externí odkaz:
https://doaj.org/article/1bffabab673f4ad09e4c5725088b169b
Akademický článek
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Autor:
Tian Huang, Xiangqing Ren, Xiaolong Tang, Yuping Wang, Rui Ji, Qinghong Guo, Qian Ma, Ya Zheng, Zenan Hu, Yongning Zhou
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Background and objectiveExtracellular adenosine (eAdo) bridges tumor metabolism and immune regulation. CD39-CD73-eAdo/A2aR axis regulates tumor microenvironment (TME) and immunotherapy response. In the era of immunotherapy, exploring the impact of th
Externí odkaz:
https://doaj.org/article/ff27416db7b549a9bf605bd96eaa5459
Autor:
Adèle Silane Delorme, Alexandra Laguide, Marie Tamagne, Marion Klea Pinheiro, Léonie Cagnet, Deborah Neyrinck-Leglantier, Mehdi Khelfa, Sabine Cleophax, France Pirenne, Benoît Vingert
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionCD39 plays an important role in the immunoregulation and inhibition of effector cells. It is expressed on immune cells, including Tregs, and on extracellular vesicles (EVs) budding from the plasma membrane. Platelet transfusion may induce
Externí odkaz:
https://doaj.org/article/fa441cd97cba440d87468d9111c26f41
Publikováno v:
BMC Immunology, Vol 24, Iss 1, Pp 1-11 (2023)
Abstract Malignant pleural effusion (MPE), which is a complex microenvironment that contains numerous immune and tumour signals, is common in lung cancer. Gene alterations, such as driver gene mutations, are believed to affect the components of tumou
Externí odkaz:
https://doaj.org/article/a419ef7aa29c4c97874b7d85ad86c077
Publikováno v:
Heliyon, Vol 10, Iss 9, Pp e29848- (2024)
Systemic lupus erythematosus (SLE) is a complex autoimmune disease with multiple etiological factors. Immune disorder contributes to SLE development and is an important clinical manifestation of SLE patients. Immune dysfunction is characterized by ab
Externí odkaz:
https://doaj.org/article/b0707d7a2b8e486bbc6f3c73ac66feff
Autor:
Leona Dold, Sandra Kalthoff, Leonie Frank, Taotao Zhou, Pia Esser, Philipp Lutz, Christian P. Strassburg, Ulrich Spengler, Bettina Langhans
Publikováno v:
Immunity, Inflammation and Disease, Vol 12, Iss 4, Pp n/a-n/a (2024)
Abstract Introduction Regulatory CD4+ T cells (Tregs) are pivotal for inhibition of autoimmunity. Primary sclerosing cholangitis (PSC) is an autoimmune cholestatic liver disease of unknown etiology where contribution of Tregs is still unclear. Activa
Externí odkaz:
https://doaj.org/article/7cd084b0cd3e473e8b9e1ed6e1b04526