Zobrazeno 1 - 10
of 59
pro vyhledávání: '"CD26/DPP4"'
Autor:
Maria L. Elkjaer, Tobias Frisch, Richard Reynolds, Tim Kacprowski, Mark Burton, Torben A. Kruse, Mads Thomassen, Jan Baumbach, Zsolt Illes
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-17 (2019)
Abstract To identify pathogenetic markers and potential drivers of different lesion types in the white matter (WM) of patients with progressive multiple sclerosis (PMS), we sequenced RNA from 73 different WM areas. Compared to 25 WM controls, 6713 ou
Externí odkaz:
https://doaj.org/article/d6c83e801176419788562e1f9dd05599
Autor:
Maria L. Elkjaer, Tobias Frisch, Richard Reynolds, Tim Kacprowski, Mark Burton, Torben A. Kruse, Mads Thomassen, Jan Baumbach, Zsolt Illes
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-17 (2019)
Abstract The heterogeneity of multiple sclerosis is reflected by dynamic changes of different lesion types in the brain white matter (WM). To identify potential drivers of this process, we RNA-sequenced 73 WM areas from patients with progressive MS (
Externí odkaz:
https://doaj.org/article/852aa60c33054bdd98dadf9bebfe5b2d
Publikováno v:
Molecules, Vol 27, Iss 14, p 4498 (2022)
The enzymatic activity of CD26/DPP4 (dipeptidyl peptidase 4/DPP4) is highlighted in multiple studies to play a vital role in glucose metabolism by cleaving and inactivating the incretins glucagon-like peptide-1 (GLP) and gastric inhibitory protein (G
Externí odkaz:
https://doaj.org/article/c406767550164b48b78b8fa12932ef36
Autor:
Rita S. Patarrão, Nádia Duarte, Inês Coelho, Joey Ward, Rogério T. Ribeiro, Maria João Meneses, Rita Andrade, João Costa, Isabel Correia, José Manuel Boavida, Rui Duarte, Luís Gardete-Correia, José Luís Medina, Jill Pell, John Petrie, João F. Raposo, Maria Paula Macedo, Carlos Penha-Gonçalves
Aims/hypothesis Imbalances in glucose metabolism are hallmarks of clinically silent prediabetes (defined as impaired fasting glucose and/or impaired glucose tolerance) representing dysmetabolism trajectories leading to type 2 diabetes. CD26/dipeptidy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f1f2f45fb048d420faa97c072f217fe
https://hdl.handle.net/10362/134691
https://hdl.handle.net/10362/134691
Publikováno v:
Cell and Tissue Research
Dipeptidyl-peptidase IV (CD26), a multifactorial integral type II protein, is expressed in the lungs during development and is involved in inflammation processes. We tested whether daily LPS administration influences the CD26-dependent retardation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60087ae2b7727fcb9da0f0bead117612
https://opus4.kobv.de/opus4-fau/files/22205/s00441-021-03522-8.pdf
https://opus4.kobv.de/opus4-fau/files/22205/s00441-021-03522-8.pdf
Publikováno v:
Frontiers in Immunology, Vol 6 (2015)
Dipeptidyl peptidase 4 (DPP4) is a glycoprotein of 110 kDa, which is ubiquitously expressed on the surface of a variety of cells. This exopeptidase selectively cleaves N-terminal dipeptides from a variety of substrates, including cytokines, growth fa
Externí odkaz:
https://doaj.org/article/3bcaa864c3e44e678ab8a39560c39b0c
Akademický článek
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Publikováno v:
Inflammation Research
Background Pseudomonas aeruginosa (PA) is the most important opportunistic pathogen in causing nosocomial infections and, furthermore, poses a permanent threat for severe chronic infections in patients with cystic fibrosis or COPD. The transmembrane
Autor:
Tim Kacprowski, Mads Thomassen, Torben A Kruse, Zsolt Illes, Maria L. Elkjaer, Mark Burton, Richard Reynolds, Tobias Frisch, Jan Baumbach
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-17 (2019)
The heterogeneity of multiple sclerosis is reflected by dynamic changes of different lesion types in the brain white matter (WM). To identify potential drivers of this process, we RNA-sequenced 73 WM areas from patients with progressive MS (PMS) and
Autor:
Torben A Kruse, Mads Thomassen, Jan Baumbach, Zsolt Illes, Tobias Frisch, Tim Kacprowski, Richard Reynolds, Mark Burton, Maria L. Elkjaer
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-17 (2019)
Elkjaer, M L, Frisch, T, Reynolds, R, Kacprowski, T, Burton, M, Kruse, T A, Thomassen, M, Baumbach, J & Illes, Z 2019, ' Molecular signature of different lesion types in the brain white matter of patients with progressive multiple sclerosis ', Acta Neuropathologica Communications, vol. 7, 205 . https://doi.org/10.1186/s40478-019-0855-7
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-17 (2019)
Elkjaer, M L, Frisch, T, Reynolds, R, Kacprowski, T, Burton, M, Kruse, T A, Thomassen, M, Baumbach, J & Illes, Z 2019, ' Molecular signature of different lesion types in the brain white matter of patients with progressive multiple sclerosis ', Acta Neuropathologica Communications, vol. 7, 205 . https://doi.org/10.1186/s40478-019-0855-7
To identify pathogenetic markers and potential drivers of different lesion types in the white matter (WM) of patients with progressive multiple sclerosis (PMS), we sequenced RNA from 73 different WM areas. Compared to 25 WM controls, 6713 out of 18,6