Výsledky vyhledávání - "CD14, Cluster of differentiation 14"

Akademický článek

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Sexual Dimorphic Role of CD14 (Cluster of Differentiation 14) in Salt-Sensitive Hypertension and Renal Injury

Autor: David L. Mattson, Rebekah L. Gundry, John Henry Dasinger, Theodore Keppel, Hayley Lund, Jeylan Zemaj, Daniel J. Fehrenbach, Mary Cherian-Shaw, Justine M. Abais-Battad, Melinda R. Dwinell, Aron M. Geurts

Publikováno v: Hypertension. 77:228-240

Genomic sequence and gene expression association studies in animals and humans have identified genes that may be integral in the pathogenesis of various diseases. CD14 (cluster of differentiation 14)—a cell surface protein involved in innate immune

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae11cd7f8bfc652c9d8e4967bb3d91e5
https://doi.org/10.1161/hypertensionaha.120.14928

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Akademický článek

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Elevated CD14 (Cluster of Differentiation 14) and Toll-Like Receptor (TLR) 4 Signaling Deteriorate Periapical Inflammation in TLR2 Deficient Mice

Autor: Winston Patrick Kuo, Laila A. Bahammam, Shuang Xu, Philip Stashenko, Alexander J. Trachtenberg, Kimito Hirai, Hajime Sasaki, Daniel B. Rider, Mako Susa, Akira Fujimura, Hisako Furusho

Publikováno v: The Anatomical Record. 299:1281-1292

Apical periodontitis (periapical lesions) is an infection-induced chronic inflammation in the jaw, ultimately resulting in the destruction of apical periodontal tissue. Toll-like receptors (TLRs) are prominent in the initial recognition of pathogens.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3aa2b98150647fe12bff9cbeec2ab230
https://doi.org/10.1002/ar.23383

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Akademický článek

Genetic and Epigenetic Regulation of the Innate Immune Response to Gout.

Autor: de Lima, Jordana Dinorá¹ (AUTHOR), de Paula, André Guilherme Portela¹ (AUTHOR), Yuasa, Bruna Sadae¹ (AUTHOR), de Souza Smanioto, Caio Cesar¹ (AUTHOR), da Cruz Silva, Maria Clara¹ (AUTHOR), dos Santos, Priscila Ianzen² (AUTHOR), Prado, Karin Braun³ (AUTHOR), Winter Boldt, Angelica Beate^2,3 (AUTHOR), Braga, Tárcio Teodoro^1,4 (AUTHOR) tarcio.braga@ufpr.br

Publikováno v: Immunological Investigations. Apr2023, Vol. 52 Issue 3, p364-397. 34p.

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Role of toll-like receptor 7/8 pathways in regulation of interferon response and inflammatory mediators during SARS-CoV2 infection and potential therapeutic options

Autor: Rahul Singh, Sean N. Avedissian, Vinod D. Chaudhari, Anthony T. Podany, Ganesh P. Pawar, Deepak B. Salunke, Rohini Emani, Shetty Ravi Dyavar, Courtney V. Fletcher

Publikováno v: Biomedicine & Pharmacotherapy, Vol 141, Iss, Pp 111794-(2021)
Biomedicine & Pharmacotherapy

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) is the causative agent of Corona Virus Disease 2019 (COVID-19). Lower production of type I and III interferons and higher levels of inflammatory mediators upon SARS-CoV2 infection contribute

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0354b118d4b1b6946482534bec88d63f
http://www.sciencedirect.com/science/article/pii/S075333222100576X

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The impact of episporic modification of

Autor: Mohamed I Abdelwahab, Hassan, Monique, Keller, Michael, Hillger, Ulrike, Binder, Stefanie, Reuter, Kristina, Herold, Anusha, Telagathoti, Hans-Martin, Dahse, Saiedeh, Wicht, Nora, Trinks, Sandor, Nietzsche, Tanja, Deckert-Gaudig, Volker, Deckert, Ralf, Mrowka, Ulrich, Terpitz, Hans, Peter Saluz, Kerstin, Voigt

Publikováno v: Computational and Structural Biotechnology Journal

Graphical abstract
Fungal infections caused by the ancient lineage Mucorales are emerging and increasingly reported in humans. Comprehensive surveys on promising attributes from a multitude of possible virulence factors are limited and so far, f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::aa4aa19cf4bf0f4d344230a88ea6dcd8
https://pubmed.ncbi.nlm.nih.gov/33598103

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Natural products as LSD1 inhibitors for cancer therapy

Autor: Xiaochuan Li, Chao Yang, Yuan Fang, Guochao Liao, Bin Yu, Qingchun Mu, Zhiqiang Yu

Publikováno v: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 621-631 (2021)
Acta Pharmaceutica Sinica B

Natural products generally fall into the biologically relevant chemical space and always possess novel biological activities, thus making them a rich source of lead compounds for new drug discovery. With the recent technological advances, natural pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee67172081a717a9c2539e0b3e363442
https://pubmed.ncbi.nlm.nih.gov/32837872

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Human cholesteryl ester transfer protein lacks lipopolysaccharide transfer activity, but worsens inflammation and sepsis outcomes in mice

Autor: Thomas Gautier, Kevin van Dongen, Émilie Charron, Stéphane Mandard, Valérie Deckert, Jean-Paul Pais de Barros, Hélène Choubley, Jérôme Labbé, Naig Le Guern, Jacques Grober, Alois Dusuel, Laurent Lagrost

Publikováno v: Journal of Lipid Research
Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2020, pp.jlr.RA120000704. ⟨10.1194/jlr.RA120000704⟩
Journal of Lipid Research, Vol 62, Iss, Pp 100011-(2021)
Journal of Lipid Research, 2020, pp.jlr.RA120000704. ⟨10.1194/jlr.RA120000704⟩

International audience; Bacterial lipopolysaccharides (LPSs or endotoxins) can bind most proteins of the lipid transfer/LPS-binding protein (LT/LBP) family in host organisms. The LPS-bound LT/LBP proteins then trigger either an LPS-induced proinflamm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd34527c453da1363375ba2659935a9
https://www.hal.inserm.fr/inserm-03052637

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Role of gut microbiota and oxidative stress in the progression of non-alcoholic fatty liver disease to hepatocarcinoma: Current and innovative therapeutic approaches

Autor: F. Tuccillo, Joseph L. Evans, Antonella Borrelli, Franco M. Buonaguro, Ira D. Goldfine, P. Bonelli, Aldo Mancini

Publikováno v: Redox Biology, Vol 15, Iss C, Pp 467-479 (2018)
Redox Biology

Non-alcoholic fatty liver disease (NAFLD) represents the most common chronic liver disease in industrialized countries. NAFLD progresses through the inflammatory phase of non-alcoholic steatohepatitis (NASH) to fibrosis and cirrhosis, with some cases

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2419fc2467afc0fef89a4f91dd16f4c
http://www.sciencedirect.com/science/article/pii/S2213231717309291

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