Zobrazeno 1 - 10
of 10
pro vyhledávání: '"CD, Chow diet"'
Autor:
Carlos Castaño, Gema Alcarraz-Vizán, Marcelina Párrizas, Sara de Pablo, Júlia Rodríguez-Comas, Joan-Marc Servitja, Mario Vallejo, Antonio Fernández-Pérez, Sara Ramírez, Daniela Díaz-Catalán, Anna Novials, Marc Claret
Publikováno v:
Molecular Metabolism
Digital.CSIC. Repositorio Institucional del CSIC
instname
Molecular Metabolism, Vol 53, Iss, Pp 101251-(2021)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Molecular Metabolism, Vol 53, Iss, Pp 101251-(2021)
© 2021 The Author(s).
[Objective]: Pancreatic β-cell dysfunction is a central feature in the pathogenesis of type 2 diabetes (T2D). Accumulating evidence indicates that β-site APP-cleaving enzyme 2 (BACE2) inhibition exerts a beneficial effec
[Objective]: Pancreatic β-cell dysfunction is a central feature in the pathogenesis of type 2 diabetes (T2D). Accumulating evidence indicates that β-site APP-cleaving enzyme 2 (BACE2) inhibition exerts a beneficial effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7198fe332721e3e3ed6c3444b9e281b
http://europepmc.org/articles/PMC8190493
http://europepmc.org/articles/PMC8190493
Autor:
Randall L. Mynatt, Sheila R. Costford, Stephen J. Gardell, Bram Brouwers, David A. Sinclair, Lauren M. Sparks, Heather H. Cornnell, Julio E. Ayala, Hui Xie, Meghan E. Hopf, Fanchao Yi, Glenn A. Walter, Steven R. Smith, Timothy F. Osborne, Chris Petucci, Mauro Dispagna, Peter E. Phelan, Ana P. Gomes
Publikováno v:
Molecular Metabolism, Vol 7, Iss, Pp 1-11 (2018)
Molecular Metabolism
Molecular Metabolism
Objective Nicotinamide phosphoribosyl transferase (NAMPT) is the rate-limiting enzyme in the salvage pathway that produces nicotinamide adenine dinucleotide (NAD+), an essential co-substrate regulating a myriad of signaling pathways. We produced a mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a89a01374700cb489521f89013a4e5f9
https://doi.org/10.1016/j.molmet.2017.10.012
https://doi.org/10.1016/j.molmet.2017.10.012
Publikováno v:
Redox Biology, Vol 12, Iss, Pp 438-455 (2017)
Redox Biology
Redox Biology
Resolvins are a novel class of lipid mediators that play an important role in the resolution of inflammation, although the underlying mechanisms are not very clear. To explore the anti-inflammatory mechanisms of resolvins, we have studied the effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2456946e21afa8586484a8732cb972ef
http://www.sciencedirect.com/science/article/pii/S2213231717300642
http://www.sciencedirect.com/science/article/pii/S2213231717300642
Autor:
Michael D. Cameron, Qingzhang Zhu, Haifei Xu, James C. Barrow, Alice Asteian, Hua Lin, Baoji Xu, Sarbani Ghoshal, Theodore M. Kamenecka, Anutosh Chakraborty, Glen Ernst
Publikováno v:
Molecular Metabolism, Vol 5, Iss 10, Pp 903-917 (2016)
Molecular Metabolism
Molecular Metabolism
Objective Obesity and type 2 diabetes (T2D) lead to various life-threatening diseases such as coronary heart disease, stroke, osteoarthritis, asthma, and neurodegeneration. Therefore, extensive research is ongoing to identify novel pathways that can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d11f5485a9473d413c3f70ce3dea24
Autor:
Yanting Xu, Taiyong Yu, Gongshe Yang, Xiaoge Zhou, Xiaochang Chen, Kuilong Huang, Xiaoyu Wang, Chen Zhao, Weijun Pang, Yulong Wang
Publikováno v:
The Journal of Biological Chemistry
With the improvement of people's living standards, the number of obese patients has also grown rapidly. It is reported that the level of oxidative stress in obese patients has significantly increased, mainly caused by the increase in reactive oxygen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa01fa7d58c64d44260d6ff949f10acc
https://doi.org/10.1074/jbc.ra120.014793
https://doi.org/10.1074/jbc.ra120.014793
Autor:
Liu Yang, Xunde Xian, Xiao Lin, Feng Wang, George Liu, Haibo Zhu, Kai Qu, Nathan Cong, Liqing Yu, Xin Guo, Jinjie Wang, Mingming Gao, Xiangbo An, Yunan Wang, Yuhui Wang
Publikováno v:
EBioMedicine
EBioMedicine, Vol 27, Iss C, Pp 214-224 (2018)
EBioMedicine, Vol 28, Iss C, Pp 17-18 (2018)
EBioMedicine, Vol 27, Iss C, Pp 214-224 (2018)
EBioMedicine, Vol 28, Iss C, Pp 17-18 (2018)
Familial hypercholesterolemia (FH) is an autosomal dominant genetic disease caused mainly by LDL receptor (Ldlr) gene mutations. Unlike FH patients, heterozygous Ldlr knockout (KO) mice do not show a dominant FH trait. Hamsters, like humans, have the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9513d389b0666abb448ff5e49a748f48
https://pubmed.ncbi.nlm.nih.gov/29289533
https://pubmed.ncbi.nlm.nih.gov/29289533
Autor:
Jean-Marie Launay, Yves Rouillé, Patty Chen, Marc Foretz, Christophe Magnan, Ralf Jockers, Koichiro Ozawa, Stéphanie Migrenne, Jacques Mallet, Toru Hosoi, Clara Roujeau, Virginie Vauthier, Chamsy Sarkis, Julie Dam
Publikováno v:
Molecular metabolism
Molecular metabolism, Elsevier, 2017, 6 (1), pp.159-172. ⟨10.1016/j.molmet.2016.10.009⟩
Molecular metabolism, 2017, 6 (1), pp.159-172. ⟨10.1016/j.molmet.2016.10.009⟩
Molecular metabolism, Elsevier, 2017, 6 (1), pp.159-172. 〈10.1016/j.molmet.2016.10.009〉
Molecular Metabolism
Molecular Metabolism, Vol 6, Iss 1, Pp 159-172 (2017)
Molecular metabolism, Elsevier, 2017, 6 (1), pp.159-172. ⟨10.1016/j.molmet.2016.10.009⟩
Molecular metabolism, 2017, 6 (1), pp.159-172. ⟨10.1016/j.molmet.2016.10.009⟩
Molecular metabolism, Elsevier, 2017, 6 (1), pp.159-172. 〈10.1016/j.molmet.2016.10.009〉
Molecular Metabolism
Molecular Metabolism, Vol 6, Iss 1, Pp 159-172 (2017)
The hypothalamic arcuate nucleus (ARC) is a major integration center for energy and glucose homeostasis that responds to leptin. Resistance to leptin in the ARC is an important component of the development of obesity and type 2 diabetes. Recently, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d3dd07a430881bcef302830b13ab301
https://hal.sorbonne-universite.fr/hal-01501632/file/1-s2.0-S2212877816302186-main.pdf
https://hal.sorbonne-universite.fr/hal-01501632/file/1-s2.0-S2212877816302186-main.pdf
Autor:
Vauthier V; Institut Cochin, Inserm U1016, CNRS UMR 8104, University Paris Descartes, Sorbonne Paris Cite, Paris, France., Roujeau C; Institut Cochin, Inserm U1016, CNRS UMR 8104, University Paris Descartes, Sorbonne Paris Cite, Paris, France., Chen P; Institut Cochin, Inserm U1016, CNRS UMR 8104, University Paris Descartes, Sorbonne Paris Cite, Paris, France., Sarkis C; University Paris Pierre et Marie Curie (UPMC), CNRS UMR 7091, NewVectys, Paris, France., Migrenne S; University Paris Diderot, Sorbonne Paris Cité, CNRS UMR8251, Paris, France., Hosoi T; Hiroshima University, Hiroshima, Japan., Ozawa K; Hiroshima University, Hiroshima, Japan., Rouillé Y; University of Lille, CNRS UMR 8204, Inserm U1019, CHU Lille, Institut Pasteur de Lille, Center for Infection and Immunity of Lille, Lille, France., Foretz M; Institut Cochin, Inserm U1016, CNRS UMR 8104, University Paris Descartes, Sorbonne Paris Cite, Paris, France., Mallet J; University Paris Pierre et Marie Curie (UPMC), CNRS UMR 7091, NewVectys, Paris, France., Launay JM; Assistance Publique des Hôpitaux de Paris (AP-HP), Université Paris Descartes, Inserm U942, Paris, France., Magnan C; University Paris Diderot, Sorbonne Paris Cité, CNRS UMR8251, Paris, France., Jockers R; Institut Cochin, Inserm U1016, CNRS UMR 8104, University Paris Descartes, Sorbonne Paris Cite, Paris, France., Dam J; Institut Cochin, Inserm U1016, CNRS UMR 8104, University Paris Descartes, Sorbonne Paris Cite, Paris, France. Electronic address: julie.dam@inserm.fr.
Publikováno v:
Molecular metabolism [Mol Metab] 2016 Nov 03; Vol. 6 (1), pp. 159-172. Date of Electronic Publication: 2016 Nov 03 (Print Publication: 2017).
Autor:
Ghoshal S; Department of Metabolism and Aging, The Scripps Research Institute, Jupiter, FL 33458, USA., Zhu Q; Department of Metabolism and Aging, The Scripps Research Institute, Jupiter, FL 33458, USA., Asteian A; Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, FL 33458, USA., Lin H; Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, FL 33458, USA., Xu H; Department of Neuroscience, The Scripps Research Institute, Jupiter, FL 33458, USA., Ernst G; Drug Discovery Division, Lieber Institute for Brain Development, Baltimore, MD 21205, USA., Barrow JC; Drug Discovery Division, Lieber Institute for Brain Development, Baltimore, MD 21205, USA., Xu B; Department of Neuroscience, The Scripps Research Institute, Jupiter, FL 33458, USA., Cameron MD; Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, FL 33458, USA., Kamenecka TM; Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, FL 33458, USA., Chakraborty A; Department of Metabolism and Aging, The Scripps Research Institute, Jupiter, FL 33458, USA. Electronic address: achakrab@scripps.edu.
Publikováno v:
Molecular metabolism [Mol Metab] 2016 Aug 21; Vol. 5 (10), pp. 903-917. Date of Electronic Publication: 2016 Aug 21 (Print Publication: 2016).