CCR4+ Regulatory T Cells Accumulate in the Very Elderly and Correlate With Superior 8-Year Survival

Autor: Evelyna Derhovanessian, Karin Hähnel, Andrea B. Maier, Graham Pawelec, Helene Roelofs, Anton J. M. de Craen, Rudi G. J. Westendorp, Sai-Juan Chen

Publikováno v: The journals of gerontology. Series A : Biological sciences and medical sciences, 70(8), 917-23. Oxford University Press
Journal of Gerontology: Medical Sciences, 70(8), 917-923
Journals of Gerontology. Series A: Biological Sciences & Medical Sciences, 70(8), 917-923. Oxford University Press
Derhovanessian, E, Chen, S, Maier, A B, Hähnel, K, de Craen, A J M, Roelofs, H, Westendorp, R & Pawelec, G 2015, ' CCR4+ Regulatory T Cells Accumulate in the Very Elderly and Correlate With Superior 8-Year Survival ', The journals of gerontology. Series A : Biological sciences and medical sciences, vol. 70, no. 8, pp. 917-23 . https://doi.org/10.1093/gerona/glu128
Derhovanessian, E, Chen, S, Maier, A B, Hahnel, K, Craen, A J M, Roelofs, H, Westendorp, R & Pawelec, G 2015, ' CCR4(+) Regulatory T Cells Accumulate in the Very Elderly and Correlate With Superior 8-Year Survival ', Journals of Gerontology. Series A: Biological Sciences & Medical Sciences, vol. 70, no. 8, pp. 917-923 . https://doi.org/10.1093/gerona/glu128

CD4(+) regulatory T cells (Tregs) are a distinct population of T cells involved in maintaining peripheral tolerance to self-antigens. Several studies have shown increased frequency and number of Tregs in the elderly. Whether such an increase has any

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab35a55b73660e461c194fb87383a702
https://doi.org/10.1093/gerona/glu128