The long-term prognostic and predictive capacity of cyclin D1 gene amplification in 2305 breast tumours

Autor: Arian Lundberg, Linda S. Lindström, Jingmei Li, J. Chuck Harrell, Eva Darai-Ramqvist, Emmanouil G. Sifakis, Theodoros Foukakis, Charles M. Perou, Kamila Czene, Jonas Bergh, Nicholas P. Tobin

Publikováno v: Breast Cancer Research, Vol 21, Iss 1, Pp 1-10 (2019)

Abstract Background Use of cyclin D1 (CCND1) gene amplification as a breast cancer biomarker has been hampered by conflicting assessments of the relationship between cyclin D1 protein levels and patient survival. Here, we aimed to clarify its prognos

Externí odkaz: https://doaj.org/article/8be3793f16a749efa5f0ae8a141a5f09

CCND1 and FGFR1 gene amplifications are associated with reduced benefit from aromatase inhibitors in metastatic breast cancer

Autor: M. M. Kramchaninov, S. E. Kubrina, Evgeny N. Imyanitov, A. D. Mikushina, V. M. Moiseyenko, V. V. Petkau, A. O. Ivantsov, Svetlana N. Aleksakhina, A. G. Iyevleva

Publikováno v: Clinical and Translational Oncology. 23:874-881

Endocrine therapy is a mainstay for the treatment of hormone receptor-positive breast cancer (BC); however, only a fraction of patients experience a pronounced response to antagonists of estrogen signaling. There is a need to identify predictors for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eb68b3871655734e62c1e5f744c08868
https://doi.org/10.1007/s12094-020-02481-w

Prognostic and Clinicopathological Significance of CCND1/Cyclin D1 Upregulation in Melanomas: A Systematic Review and Comprehensive Meta-Analysis

Autor: Lucía González-Ruiz, Isabel Ruiz-Ávila, Pablo Ramos-García, Miguel Ángel González-Moles, Isabel González-Ruiz

Publikováno v: Digibug. Repositorio Institucional de la Universidad de Granada
instname
Cancers, Vol 13, Iss 1314, p 1314 (2021)
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)

We would like to thank the research group CTS-392 (Plan Andaluz de Investigación, Junta de Andalucía, Spain).
Simple Summary The incidence of cutaneous melanoma is increasing worldwide, currently responsible for 287,723 new cases and 60,712 de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27baa782a410f679beff14f5f1cf9c5e
http://hdl.handle.net/10481/68070

Multiple CDK/CYCLIND genes are amplified in medulloblastoma and supratentorial primitive neuroectodermal brain tumor

Autor: Wan L. Lam, Will Lockwood, Jeremy A. Squire, Maisa Yoshimoto, Cynthia Hawkins, Annie Huang, Hai Yan, Meihua Li, Charles G. Eberhart, Paul A. Northcott, Michael D. Taylor, James T. Rutka, Young Shing Ra, Eric Bouffet, Maria Zielenska

Publikováno v: Cancer Genetics. 205:220-231

Embryonal brain tumors, which include medulloblastoma and the more aggressive supratentorial primitive neuroectodermal tumor (sPNET), comprise one of the largest group of malignant pediatric brain tumors. We observed in high resolution array comparat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6318555bc7ae9f1dce43f1c39daab350
https://doi.org/10.1016/j.cancergen.2012.03.002

CCND1 amplification and cyclin D1 expression in breast cancer and their relation with proteomic subgroups and patient outcome

Autor: C. Paish, Andrew R. Green, Somaia Elsheikh, Maryou B K Lambros, Matthew J. Grainge, Mohammed A. Aleskandarany, Ian O. Ellis, Jorge S. Reis-Filho

Publikováno v: Breast Cancer Research and Treatment. 109:325-335

Despite strong evidence regarding the role of CCND1 amplification and protein overexpression in breast carcinoma, the associations between CCND1 amplification/cyclin D1 overexpression and clinicopathological variables and clinical outcome remain cont

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f72005ab6c5376364e7c5fbe6bba1713
https://doi.org/10.1007/s10549-007-9659-8