Palmitate Activates CCL4 Expression in Human Monocytic Cells via TLR4/MyD88 Dependent Activation of NF-κB/MAPK/ PI3K Signaling Systems

Autor: Shihab Kochumon, Ajit Wilson, Betty Chandy, Steve Shenouda, Jaakko Tuomilehto, Sardar Sindhu, Rasheed Ahmad

Publikováno v: Cellular Physiology and Biochemistry, Vol 46, Iss 3, Pp 953-964 (2018)

Background/Aims: Obesity is associated with adipose tissue inflammation which plays a key role in the development of insulin resistance and type 2 diabetes (T2D). Saturated free fatty acids (SFAs) levels are found to be elevated in obesity and T2D. C

Externí odkaz: https://doaj.org/article/257dddee62964ac8b0cf927621718ec1

Relation of circulating concentrations of chemokine receptor CCR5 ligands to C-peptide, proinsulin and HbA1c and disease progression in type 1 diabetes

Autor: C, Pfleger, A, Kaas, L, Hansen, B, Alizadeh, P, Hougaard, R, Holl, H, Kolb, B O, Roep, H B, Mortensen, N C, Schloot, Jan Aman, Aman

Publikováno v: Pfleger, C, Kaas, A, Hansen, L, Alizadeh, B, Hougaard, P, Holl, R, Kolb, H, Roep, B O, Mortensen, H B, Schloot, N C & Hvidøre Study Group on Childhood Diabetes 2008, ' Relation of circulating concentrations of chemokine receptor CCR5 ligands to C-peptide, proinsulin and HbA1c and disease progression in type 1 diabetes ', Clinical Immunology, vol. 128, no. 1, pp. 57-65 . https://doi.org/10.1016/j.clim.2008.03.458
Clinical Immunology, 128(1), 57-65. ACADEMIC PRESS INC ELSEVIER SCIENCE
Clinical Immunology. ACADEMIC PRESS INC ELSEVIER SCIENCE
Clinical Immunology, 128(1), 57-65. San Diego, CA: Academic Press (2008).

Th1 related chemokines CCL3 and CCL5 and Th2 related CCL4 as ligands of the receptor CCR5 contribute to disease development in animal models of type 1 diabetes. In humans, no data are available addressing the role of these chemokines regarding diseas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54e845b058937df1b22c07f6af0d5f9f
https://doi.org/10.1016/j.clim.2008.03.458

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.