Zobrazeno 1 - 10
of 91
pro vyhledávání: '"CCK, cholecystokinin"'
Autor:
Thiago M.C. Pereira, Glaucimeire R. Carvalho, María Luaces-Regueira, Ana Bugallo-Casal, Ana Iglesias-Mejuto, Lonneke Nugteren, Martina Schmidt, Dolores Viña, Elisardo C. Vasquez, Manuel Campos-Toimil
Publikováno v:
Phytomedicine Plus, Vol 2, Iss 3, Pp 100301- (2022)
Resveratrol is a natural phytoalexin present in human diet with a potential beneficial effect in many diseases including chronic and acute pancreatitis, a potentially fatal disease with significant morbimortality accompanied with obscure pathogenesis
Externí odkaz:
https://doaj.org/article/7e19d4eb16b94265aba7caed41481e23
Akademický článek
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Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 9, Iss 5, Pp 880-901 (2019)
Acta Pharmaceutica Sinica B, Vol 9, Iss 5, Pp 880-901 (2019)
The trend toward designing large hydrophobic molecules for lead optimization is often associated with poor drug-likeness and high attrition rates in drug discovery and development. Structural simplification is a powerful strategy for improving the ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccb376b89b70d546819c6896fcd6d927
https://doi.org/10.1016/j.apsb.2019.05.004
https://doi.org/10.1016/j.apsb.2019.05.004
Autor:
Liddle, Rodger A.
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Enteroendocrine cells (EECs) are sensory cells of the gastrointestinal tract. Most EECs reside in the mucosal lining of the stomach or intestine and sense food in the gut lumen. Food signals stimulate the release of hormones into the paracellular spa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703d9c678271f06df9092bf559b4cd29
https://doi.org/10.1016/j.jcmgh.2019.01.006
https://doi.org/10.1016/j.jcmgh.2019.01.006
Autor:
Julia Doller, Franziska Gisela Thiel, Frank Ulrich Weiss, Ali A. Aghdassi, M. Wiese, Anika Wilden, Laura L. De Freitas Chama, Markus M. Lerch, Robert Bolsmann, Matthias Sendler, Van Huy Tran, Jana Marielle Modenbach, Juliane Glaubitz, Quang Trung Tran
Publikováno v:
Pancreas
Acute pancreatitis (AP) is one of the most common gastroenterological disorders leading to hospitalization. It has long been debated whether biliary AP, about 30% to 50% of all cases, is induced by bile acids (BAs) when they reach the pancreas via re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b78284b0d01817a8b3f76689b03e2ea0
https://pubmed.ncbi.nlm.nih.gov/33370017
https://pubmed.ncbi.nlm.nih.gov/33370017
Autor:
Miruna Costreie, Erika Polgár, Allen C. Dickie, Oğuz Akar, Andrew M. Bell, Maria Gutierrez-Mecinas, Masahiko Watanabe, Andrew J. Todd
Publikováno v:
Neuroscience
Highlights • Substance P-expressing radial cells in lamina II receive half of their excitatory synaptic input from other interneurons. • They are preferentially innervated by transient central cells that express eGFP in a GRP-eGFP mouse line. •
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c71b05c3830273d361951bbbf377255
https://eprints.gla.ac.uk/219536/1/219536.pdf
https://eprints.gla.ac.uk/219536/1/219536.pdf
Autor:
Fred S, Gorelick
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Maintaining endoplasmic reticulum (ER) proteostasis is essential for pancreatic acinar cell function. Under conditions of severe ER stress, activation of pathogenic unfolded protein response pathways plays a central role in the deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a044cafee735a2fdb7d789859e3da5b8
https://pubmed.ncbi.nlm.nih.gov/33080365
https://pubmed.ncbi.nlm.nih.gov/33080365
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 99-115 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 99-115 (2021)
Background & Aims Chronic amino acid (AA) deficiency, as in kwashiorkor, reduces the size of the pancreas through an effect on mammalian target of rapamycin complex 1 (mTORC1). Because of the physiological importance of AAs and their role as a substr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bdfa7077fd78998f54db32a754523b3
https://pubmed.ncbi.nlm.nih.gov/32735995
https://pubmed.ncbi.nlm.nih.gov/32735995
Publikováno v:
Neuroscience
The great majority of neurons in the superficial dorsal horn of the spinal cord are excitatory interneurons, and these are required for the normal perception of pain and itch. We have previously identified 5 largely non-overlapping populations among
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d651e9db7f1b8b4c57d683220dac10
https://pubmed.ncbi.nlm.nih.gov/31421202
https://pubmed.ncbi.nlm.nih.gov/31421202