Cost effectiveness of using Faecal Immunochemical Testing (FIT) as an initial diagnostic investigation for patients with lower gastrointestinal symptoms suggestive of malignancy

Autor: CC Kearsey, C Graham, HS Lobb, J Chacko, R Weatherburn, PS Rooney

Publikováno v: BMC Family Practice, Vol 22, Iss 1, Pp 1-6 (2021)

Abstract Background There has been an increase in the numbers of patients presenting to primary care with suspected colorectal malignancy and subsequently an increase in demand for endoscopy. This study aims to forecast the cost of faecal immunochemi

Externí odkaz: https://doaj.org/article/af0f4c0c3c1949f9a2857b650cafbdbf

Profiling the compendium of changes in Saccharomyces cerevisiae due to mutations that alter availability of the main methyl donor S-Adenosylmethionine.

Autor: Remines, McKayla¹ (AUTHOR), Schoonover, Makailyn G¹ (AUTHOR), Knox, Zoey¹ (AUTHOR), Kenwright, Kailee¹ (AUTHOR), Hoffert, Kellyn M¹ (AUTHOR), Coric, Amila¹ (AUTHOR), Mead, James¹ (AUTHOR), Ampfer, Joseph¹ (AUTHOR), Seye, Serigne¹ (AUTHOR), Strome, Erin D¹ (AUTHOR) stromee1@nku.edu

Publikováno v: G3: Genes | Genomes | Genetics. Apr2024, Vol. 14 Issue 4, p1-23. 23p.

Most mitochondrial dGTP is tightly bound to respiratory complex I through the NDUFA10 subunit.

Autor: Molina-Granada, David^1,2 (AUTHOR), González-Vioque, Emiliano^1,2,3 (AUTHOR), Dibley, Marris G.⁴ (AUTHOR), Cabrera-Pérez, Raquel^1,2 (AUTHOR), Vallbona-Garcia, Antoni¹ (AUTHOR), Torres-Torronteras, Javier^1,2 (AUTHOR), Sazanov, Leonid A.⁵ (AUTHOR), Ryan, Michael T.⁴ (AUTHOR), Cámara, Yolanda^1,2 (AUTHOR) yolanda.camara@vhir.org, Martí, Ramon^1,2 (AUTHOR) ramon.marti@vhir.org

Publikováno v: Communications Biology. 6/23/2022, Vol. 5 Issue 1, p1-16. 16p.

Expression of the cancer-associated DNA polymerase ε P286R in fission yeast leads to translesion synthesis polymerase dependent hypermutation and defective DNA replication.

Autor: Soriano, Ignacio^1,2 (AUTHOR) ignacio.soriano@igmm.ed.ac.uk, Vazquez, Enrique³ (AUTHOR), De Leon, Nagore^1,2 (AUTHOR), Bertrand, Sibyl¹ (AUTHOR), Heitzer, Ellen⁴ (AUTHOR), Toumazou, Sophia^1,5 (AUTHOR), Bo, Zhihan¹ (AUTHOR), Palles, Claire⁶ (AUTHOR), Pai, Chen-Chun⁵ (AUTHOR), Humphrey, Timothy C.⁵ (AUTHOR), Tomlinson, Ian² (AUTHOR), Cotterill, Sue⁷ (AUTHOR), Kearsey, Stephen E.¹ (AUTHOR) ignacio.soriano@igmm.ed.ac.uk

Publikováno v: PLoS Genetics. 7/6/2021, Vol. 17 Issue 7, p1-27. 27p.

Chemotherapy-induced CDA expression renders resistant non-small cell lung cancer cells sensitive to 5′-deoxy-5-fluorocytidine (5′-DFCR).

Autor: Gao, Yanyun^1,2 (AUTHOR), Zens, Philipp³ (AUTHOR), Su, Min^4,5 (AUTHOR), Gemperli, Camila Anna² (AUTHOR), Yang, Haitang^1,2 (AUTHOR), Deng, Haibin^1,2 (AUTHOR), Yang, Zhang^1,2 (AUTHOR), Xu, Duo^1,2 (AUTHOR), Hall, Sean R. R.^1,2 (AUTHOR), Berezowska, Sabina^3,6 (AUTHOR), Dorn, Patrick¹ (AUTHOR), Peng, Ren-Wang^1,2 (AUTHOR), Schmid, Ralph Alexander^1,2 (AUTHOR) ralph.schmid@insel.ch, Wang, Wenxiang^4,5 (AUTHOR) hnchw11@163.com, Marti, Thomas Michael^1,2 (AUTHOR) thomas.marti@insel.ch

Publikováno v: Journal of Experimental & Clinical Cancer Research (17569966). 4/19/2021, Vol. 40 Issue 1, p1-22. 22p.