Cirrhotic portal hypertension: From pathophysiology to novel therapeutics

Autor: LS Gunarathne, Kolin Rajapaksha, N Shackel, PW Angus, CB Herath

©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. Portal hypertension and bleeding from gastroesophageal varices is the major cause of morbidity and mortality in patients with cirrhosis. Portal hypertension is i

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Editorial: Pathophysiology and pharmacological treatments associated with liver failures.

Autor: Herath CB; Department of Medicine, University of Melbourne, Austin Health, Heidelberg, Australia., El Hiba O; Laboratory of Anthropogenic, Biotechnology and Health, Nutritional Physiopathologies, Neurosciences and Toxicology Team, Faculty of Sciences, Chouaib Doukkali University, El Jadida, Morocco., Zhou X; Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences, Fudan University, Shanghai, China., Luo X; Department of Gastroenterology and Hepatology, West China Hospital, Sichuan University, Chengdu, China., Lu K; Division of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, Heinrich Heine University of Düsseldorf, Düsseldorf, Germany.

Publikováno v: Frontiers in pharmacology [Front Pharmacol] 2024 Apr 12; Vol. 15, pp. 1407835. Date of Electronic Publication: 2024 Apr 12 (Print Publication: 2024).

Angiotensin Converting Enzyme-2 Therapy Improves Liver Fibrosis and Glycemic Control in Diabetic Mice With Fatty Liver.

Autor: Rajapaksha IG; Department of MedicineThe University of MelbourneAustin HealthHeidelbergVICAustralia., Gunarathne LS; Department of MedicineThe University of MelbourneAustin HealthHeidelbergVICAustralia., Asadi K; Anatomical PathologyAustin HealthHeidelbergVICAustralia., Laybutt R; Garvan Institute of Medical ResearchSydneyNSWAustralia.; St. Vincent's Clinical SchoolUniversity of New South WalesSydneyNSWAustralia., Andrikopoulous S; Department of MedicineThe University of MelbourneAustin HealthHeidelbergVICAustralia., Alexander IE; School of MedicineUniversity of SydneyChildren's Medical Research InstituteSydneyNSWAustralia., Watt MJ; Department Anatomy and PhysiologyThe University of MelbourneMelbourneVICAustralia., Angus PW; Department of MedicineThe University of MelbourneAustin HealthHeidelbergVICAustralia.; Department GastroenterologyAustin HealthHeidelbergVICAustralia., Herath CB; Department of MedicineThe University of MelbourneAustin HealthHeidelbergVICAustralia.; South Western Sydney Clinical SchoolFaculty of MedicineUniversity of New South WalesSydneyNSWAustralia.; Ingham Institute for Applied Medical ResearchLiverpoolNSWAustralia.

Publikováno v: Hepatology communications [Hepatol Commun] 2022 May; Vol. 6 (5), pp. 1056-1072. Date of Electronic Publication: 2021 Dec 23.

Anti-Fibrotic and Anti-Angiogenic Activities of Osbeckia octandra Leaf Extracts in Thioacetamide-Induced Experimental Liver Cirrhosis.

Autor: Bogahawaththa S; Department of Animal Science, Faculty of Agriculture, University of Peradeniya, Peradeniya 20400, Sri Lanka.; The United Graduate School of Agricultural Sciences, Kagoshima University, Kagoshima 890-0065, Japan.; Laboratory of Biochemistry, Faculty of Agriculture, Saga University, Saga 840-8502, Japan., Kodithuwakku SP; Department of Animal Science, Faculty of Agriculture, University of Peradeniya, Peradeniya 20400, Sri Lanka., Wijesundera KK; Department of Veterinary Pathobiology, Faculty of Veterinary Medicine and Animal Science, University of Peradeniya, Peradeniya 20400, Sri Lanka., Siriweera EH; Department of Pathology, Faculty of Medicine, University of Peradeniya, Peradeniya 20400, Sri Lanka., Jayasinghe L; National Institute of Fundamental Studies, Hanthana Road, Kandy 20000, Sri Lanka., Dissanayaka WL; Applied Oral Sciences & Community Dental Care, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China., Rajapakse J; Department of Veterinary Pathobiology, Faculty of Veterinary Medicine and Animal Science, University of Peradeniya, Peradeniya 20400, Sri Lanka., Herath CB; Department of Medicine, Austin Health, Melbourne Medical School, The University of Melbourne, Heidelberg, VIC 3084, Australia.; South Western Sydney Clinical School and Ingham Institute for Applied Medical Research, Faculty of Medicine, University of New South Wales, Liverpool, NSW 2170, Australia., Tsujita T; The United Graduate School of Agricultural Sciences, Kagoshima University, Kagoshima 890-0065, Japan.; Laboratory of Biochemistry, Faculty of Agriculture, Saga University, Saga 840-8502, Japan., Wijayagunawardane MPB; Department of Animal Science, Faculty of Agriculture, University of Peradeniya, Peradeniya 20400, Sri Lanka.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2021 Aug 10; Vol. 26 (16). Date of Electronic Publication: 2021 Aug 10.

ACE2: from protection of liver disease to propagation of COVID-19.

Autor: Warner FJ; Department of Pharmacy, Royal Prince Alfred Hospital, Sydney, Australia., Rajapaksha H; School of Molecular Science, College of Science, La Trobe University, Melbourne, Australia., Shackel N; ANZAC Research Institute, Sydney, Australia., Herath CB; South Western Sydney Clinical School, University of New South Wales, Ingham Institute for Applied Medical Research, Sydney, Australia.; Department of Medicine, Melbourne Medical School, University of Melbourne, Melbourne, Australia.

Publikováno v: Clinical science (London, England : 1979) [Clin Sci (Lond)] 2020 Dec 11; Vol. 134 (23), pp. 3137-3158.