Sclerostin-Antibody Treatment Decreases Fracture Rates in Axial Skeleton and Improves the Skeletal Phenotype in Growing oim/oim Mice

Autor: Michael S. Ominsky, Sébastien Lafont, Mickaël Cardinal, Alicia Dessain, Daniel Chappard, Thomas Roels, Guillaume Mabilleau, Daniel Manicourt, Jean-Pierre Devogelaer, Catherine Nyssen-Behets, Patrick Ammann

Publikováno v: Calcified Tissue International
Calcified Tissue International, Springer Verlag, 2020, 106 (5), pp.494-508. ⟨10.1007/s00223-019-00655-5⟩

In osteogenesis imperfecta (OI), vertebrae brittleness causes thorax deformations and leads to cardiopulmonary failure. As sclerostin-neutralizing antibodies increase bone mass and strength in animal models of osteoporosis, their administration in tw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2ef7bd06cf621715621fe2dc6e4fed0
https://pubmed.ncbi.nlm.nih.gov/32025752

A cadaveric model of anterior compartment leg syndrome: Subcutaneous minimally invasive fasciotomy versus open fasciotomy

Autor: Benoît Lengelé, Catherine Nyssen-Behets, Simon Vandergugten, Laurent Zemmour

Publikováno v: Orthopaedics & Traumatology: Surgery & Research, Vol. 105, no.1, p. 167-171 (2019)
Orthopaedics & traumatology, surgery & research : OTSR, Vol. 105, no. 1, p. 167-171 (2019)

Because of disabling sequelae of open fasciotomy in anterior compartment syndrome (ACS) of the leg, we wanted to describe and validate a cadaveric model of ACS. We hypothesized that, first, anterior compartment syndrome (ACS) could be reproduced in c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::963c5a83af47fefbec22295028756122
https://hdl.handle.net/2078.1/217842

Chondroid bone in dinosaur embryos and nestlings (Ornithischia: Hadrosauridae): Insights into the growth of the skull and the evolution of skeletal tissues

Autor: Alida M. Bailleul, Catherine Nyssen-Behets, Benoît Lengelé, Brian K. Hall, John R. Horner

Publikováno v: Comptes rendus. Palevol, Vol. 15, no.1-2, p. 49-64 (2016)

In histology textbooks, the vertebrate skeleton is represented as almost entirely made of bone and cartilage. This is a false dichotomy and in fact, a continuum of intermediate tissues between bone and cartilage exists. Chondroid bone ([CB] or chondr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31c98d977659510b1e05e4efb1719685
https://doi.org/10.1016/j.crpv.2014.12.004

Oxidative Stress and Upregulation of Antioxidant Proteins, Including Adiponectin, in Extraocular Muscular Cells, Orbital Adipocytes, and Thyrocytes in Graves' Disease Associated with Orbitopathy

Autor: Maximin Senou, Victoria Van Regemorter, Catherine Nyssen-Behets, L Baldeschi, Marie-Christine Many, Aurélie Delaigle, Michel Mourad, Elliott Van Regemorter, Benoît Lengelé, Antonella Boschi, Julie Craps, Alexis Werion, Lancelot Marique, Chantal Daumerie, Sonia Brichard

Publikováno v: Thyroid. 25:1033-1042

Graves' orbitopathy (GO) is the main extrathyroidal manifestation associated with Graves' disease (GD). It is characterized by reduced eye motility due to an increased volume of orbital fat and/or of extraocular muscles (EOMs) infiltrated by fibrosis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6400f010a538081d9fda492230ae178
https://doi.org/10.1089/thy.2015.0087

Molecular Study of a Hoxa2 Gain-of-Function in Chondrogenesis: A Model of Idiopathic Proportionate Short Stature

Autor: René Rezsohazy, Benoît Lengelé, Catherine Nyssen-Behets, Pierre M. L. Deprez, Miloud G. Nichane

Publikováno v: International journal of molecular sciences, Vol. 14, no. 10, p. 20386-20398 (2013)
International Journal of Molecular Sciences, Vol 14, Iss 10, Pp 20386-20398 (2013)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 14; Issue 10; Pages: 20386-20398

In a previous study using transgenic mice ectopically expressing Hoxa2 during chondrogenesis, we associated the animal phenotype to human idiopathic proportionate short stature. Our analysis showed that this overall size reduction was correlated with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbbd86f2604292ec4dca165b3e55ea06
https://doi.org/10.3390/ijms141020386