Zobrazeno 1 - 10
of 87
pro vyhledávání: '"CAROLINE H. DAMSKY"'
Autor:
Jill A. Helms, Caroline H. Damsky, Yu Jin Park, Philipp Leucht, Cynthia A. Luppen, Jae-Beom Kim, Hilary E. Beggs
Publikováno v:
Bone. 41:39-51
Integrins link the inside of a cell with its outside environment and in doing so regulate a wide variety of cell behaviors. Integrins are well known for their roles in angiogenesis and cell migration but their functions in bone formation are less cle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::725c4b140f2eed1ffd3d2264e5dec899
https://doi.org/10.1016/j.bone.2007.01.024
https://doi.org/10.1016/j.bone.2007.01.024
Autor:
Katsuji Shimizu, Akitoshi Jikko, Caroline H. Damsky, Nobuhiro Kamiya, Hideto Watanabe, Koji Kimata
Publikováno v:
Journal of Bone and Mineral Research. 17:1832-1842
We established a clonal chondrocytic cell line N1511 derived from rib cartilage of a p53-null mouse. N1511 cells proliferated in polygonal shape and elicited differentiation at confluence when treated with combination of bone morphogenetic protein (B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee2516b1cb26eef0bd1a9cad8abd5822
https://doi.org/10.1359/jbmr.2002.17.10.1832
https://doi.org/10.1359/jbmr.2002.17.10.1832
Autor:
Kathryn L. Crossin, Caroline H. Damsky, Donald E. Ingber, Donald P. Bottaro, Patricia Ducy, Mohammad A. Heidaran
Publikováno v:
Annals of the New York Academy of Sciences. 961:164-167
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c924098619712ec67ac379657e336e9
https://doi.org/10.1111/j.1749-6632.2002.tb03075.x
https://doi.org/10.1111/j.1749-6632.2002.tb03075.x
Autor:
Diana Graus-Porta, Amanda Littlewood-Evans, Johannes C. Schittny, Rüdiger Klein, Ulrich Müller, Paul C. Orban, Sandra Blaess, Zhen Huang, Caroline H. Damsky, Mathias Senften
Publikováno v:
Graus-Porta, Diana; Blaess, Sandra; Senften, Mathias; Littlewood-Evans, Amanda; Damsky, Caroline; Huang, Zhen; Orban, Paul; Klein, Rüdiger; Schittny, Johannes C.; Müller, Ulrich (2001). β1-Class Integrins Regulate the Development of Laminae and Folia in the Cerebral and Cerebellar Cortex. Neuron, 31(3), pp. 367-379. Cell Press 10.1016/S0896-6273(01)00374-9
Mice that lack all beta1-class integrins in neurons and glia die prematurely after birth with severe brain malformations. Cortical hemispheres and cerebellar folia fuse, and cortical laminae are perturbed. These defects result from disorganization of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::225dc137d552e44f42dcae8e0bc8b6a2
Autor:
David G. Gardner, Frederick Roediger, Eduardo A. C. Almeida, Dusko Ilic, Caroline H. Damsky, Branka Kovacic-Milivojevic
Publikováno v:
Molecular Biology of the Cell. 12:2290-2307
Hypertrophic terminally differentiated cardiac myocytes show increased sarcomeric organization and altered gene expression. Previously, we established a role for the nonreceptor tyrosine kinase Src in signaling cardiac myocyte hypertrophy. Here we re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b99eee6f74562a5b4f10d0c234dc1387
https://doi.org/10.1091/mbc.12.8.2290
https://doi.org/10.1091/mbc.12.8.2290
Autor:
Fang Jin, Eduardo Caceres, Susan J. Fisher, Caroline H. Damsky, Dusko Ilic, Olga Genbacev, Erik Schaefer, Valerie Bellingard-Dubouchaud, Eduardo A. C. Almeida
Publikováno v:
The American Journal of Pathology. 159:93-108
During human pregnancy specialized placental cells of fetal origin, termed cytotrophoblasts, invade the uterus and its blood vessels. This tumor-like process anchors the conceptus to the mother and diverts the flow of uterine blood to the placenta. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eadaa65dbb207bb835157bb89febee7
https://doi.org/10.1016/s0002-9440(10)61677-x
https://doi.org/10.1016/s0002-9440(10)61677-x
Autor:
Christof R. Hauck, David D. Schlaepfer, Eduardo A. C. Almeida, Dusko Ilic, Hisaaki Kawakatsu, Caroline H. Damsky, Fang Jin, Qin Han
Publikováno v:
The Journal of Cell Biology
Most transformed cells have lost anchorage and serum dependence for growth and survival. Previously, we established that when serum is absent, fibronectin survival signals transduced by focal adhesion kinase (FAK), suppress p53-regulated apoptosis in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c77fbb990c75b9209eaa3e9dfde658b
https://doi.org/10.1083/jcb.149.3.741
https://doi.org/10.1083/jcb.149.3.741
Publikováno v:
Developmental Biology. 220:2-15
To determine the role of integrins in mature osteoblasts in vivo, we expressed in transgenic mice a dominant-negative integrin subunit (beta1-DN) consisting of the beta1 subunit cytoplasmic and transmembrane domains, driven by the osteoblast-specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f84721845cbf9a007ab9b0167e55d4e5
https://doi.org/10.1006/dbio.2000.9633
https://doi.org/10.1006/dbio.2000.9633
Autor:
David J. Sieg, Caroline H. Damsky, Dusko Ilic, Erik Schaefer, Christof R. Hauck, David D. Schlaepfer, Candice K. Klingbeil
Publikováno v:
Nature Cell Biology. 2:249-256
Here we show that cells lacking focal adhesion kinase (FAK) are refractory to motility signals from platelet-derived and epidermal growth factors (PDGF and EGF respectively), and that stable re-expression of FAK rescues these defects. FAK associates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3a6e7da64ee10af7f2db1ecc5b3208f
https://doi.org/10.1038/35010517
https://doi.org/10.1038/35010517
Autor:
Elena Caveggion, Patrick W. Suen, Giorgio Berton, Caroline H. Damsky, Clifford A. Lowell, Dusko Ilic
Publikováno v:
Journal of Cell Science. 112:4067-4078
Integrin-mediated adhesion of monocytes and macrophages initiates a signal transduction pathway that leads to actin cytoskeletal reorganization, cell migration and immunologic activation. This signaling pathway is critically dependent on tyrosine kin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae5659c5efd3d0debc88fb73ad9893a8
https://doi.org/10.1242/jcs.112.22.4067
https://doi.org/10.1242/jcs.112.22.4067