Zobrazeno 1 - 10
of 53
pro vyhledávání: '"CARLOS BERNAL-MIZRACHI"'
Autor:
Jisu Oh, Amy E. Riek, Kevin T. Bauerle, Adriana Dusso, Kyle P. McNerney, Ruteja A. Barve, Isra Darwech, Jennifer E. Sprague, Clare Moynihan, Rong M. Zhang, Greta Kutz, Ting Wang, Xiaoyun Xing, Daofeng Li, Marguerite Mrad, Nicholas M. Wigge, Esmeralda Castelblanco, Alejandro Collin, Monika Bambouskova, Richard D. Head, Mark S. Sands, Carlos Bernal-Mizrachi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Environmental factors may alter the fetal genome to cause metabolic diseases. It is unknown whether embryonic immune cell programming impacts the risk of type 2 diabetes in later life. We demonstrate that transplantation of fetal hematopoiet
Externí odkaz:
https://doaj.org/article/006bb5f74e894a5ca7b478ca55888534
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Chronic Kidney Disease (CKD), a disorder that affects 11% of the world's population, is characterized by an acceleration in skeletal, immune, renal, and cardiovascular aging that increases the risk of cardiovascular mortality by 10- to 20-fold, compa
Externí odkaz:
https://doaj.org/article/690904b285994bd99671f296ac4db44a
Autor:
Jisu Oh, Amy E. Riek, Isra Darwech, Katsuhiko Funai, JianSu Shao, Kathleen Chin, Oscar L. Sierra, Geert Carmeliet, Richard E. Ostlund Jr., Carlos Bernal-Mizrachi
Publikováno v:
Cell Reports, Vol 10, Iss 11, Pp 1872-1886 (2015)
Intense effort has been devoted to understanding predisposition to chronic systemic inflammation because it contributes to cardiometabolic disease. We demonstrate that deletion of the macrophage vitamin D receptor (VDR) in mice (KODMAC) is sufficient
Externí odkaz:
https://doaj.org/article/bc5131ee1f884f2a8768b841a92cbe05
Autor:
Karen Tordjman, Kara N. Standley, Carlos Bernal-Mizrachi, Teresa C. Leone, Trey Coleman, Daniel P. Kelly, Clay F. Semenkovich
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 6, Pp 936-943 (2002)
Fatty acids may promote type 2 diabetes by altering insulin secretion from pancreatic β cells, a process known as lipotoxicity. The underlying mechanisms are poorly understood. To test the hypothesis that peroxisome proliferator-activated receptor
Externí odkaz:
https://doaj.org/article/654bd31385d441d4b49a4be13fa183a5
Autor:
Sherry Weng, Jennifer E Sprague, Jisu Oh, Amy E Riek, Kathleen Chin, Miguel Garcia, Carlos Bernal-Mizrachi
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54625 (2013)
Multiple epidemiological studies link vitamin D deficiency to increased cardiovascular disease (CVD), but causality and possible mechanisms underlying these associations are not established. To clarify the role of vitamin D-deficiency in CVD in vivo,
Externí odkaz:
https://doaj.org/article/d3765db41f1644918661d03456cd81f4
Autor:
Pin Yue, Zhouji Chen, Fatiha Nassir, Carlos Bernal-Mizrachi, Brian Finck, Salman Azhar, Nada A Abumrad
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9906 (2010)
CD36 facilitates oxidized low density lipoprotein uptake and is implicated in development of atherosclerotic lesions. CD36 also binds unmodified high and very low density lipoproteins (HDL, VLDL) but its role in the metabolism of these particles is u
Externí odkaz:
https://doaj.org/article/0aade42afc04473986b942778bd5465b
Autor:
Teresa C Leone, John J Lehman, Brian N Finck, Paul J Schaeffer, Adam R Wende, Sihem Boudina, Michael Courtois, David F Wozniak, Nandakumar Sambandam, Carlos Bernal-Mizrachi, Zhouji Chen, John O Holloszy, Denis M Medeiros, Robert E Schmidt, Jeffrey E Saffitz, E Dale Abel, Clay F Semenkovich, Daniel P Kelly
Publikováno v:
PLoS Biology, Vol 3, Iss 4, p e101 (2005)
The gene encoding the transcriptional coactivator peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) was targeted in mice. PGC-1alpha null (PGC-1alpha(-/-)) mice were viable. However, extensive phenotyping revealed multi
Externí odkaz:
https://doaj.org/article/16bb1d9b02ff480aa13aad3087d82569
Autor:
Jisu Oh, Amy E. Riek, Kevin T. Bauerle, Adriana Dusso, Kyle P. McNerney, Ruteja A. Barve, Isra Darwech, Jennifer Sprague, Clare Moynihan, Rong M Zhang, Ting Wang, Xiaoyun Xing, Daofeng Li, Richard D. Head, Monika Bambouskova, Marguerite Mrad, Alejandro Collins, Mark S. Sands, Carlos Bernal-Mizrachi
Environmental factors may alter the fetal genome to cause metabolic diseases. It is unknown whether embryonic immune cell programming impacts the risk of type 2 diabetes in later life. We demonstrate that transplantation of fetal hematopoietic stem c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c37639e53868c652b29c0eceabbc834
https://doi.org/10.1101/2022.09.08.507174
https://doi.org/10.1101/2022.09.08.507174
Autor:
RONG MEI ZHANG, JISU OH, GRETA A. KUTZ, MONIKA BAMBOUSKOVA, ADRIANA S. DUSSO, CARLOS BERNAL-MIZRACHI
Publikováno v:
Diabetes. 71
Background: Cardiovascular disease (CVD) is an inflammatory disorder enhanced by diabetes. The mechanisms by which recurrent acute hyperglycemia promotes inflammation and CVD are unclear. We showed that acute hyperglycemia mediates increased monocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c3d48a5e0e64493536ebf0f9b0b8bcb
https://doi.org/10.2337/db22-412-p
https://doi.org/10.2337/db22-412-p
Autor:
Mark B. Meyer, Carlos Bernal-Mizrachi, Daniel D. Bikle, Madhu Biyani, Moray J. Campbell, Snehal N. Chaudhari, Sylvia Christakos, Sue A. Ingles, Megan M. Knuth, Seong Min Lee, Thomas S. Lisse, Eva S. Liu, Isabelle Piec, Lori A. Plum, Sudhaker D. Rao, Carmen J. Reynolds, Tom D. Thacher, John H. White, Margherita T. Cantorna
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 228:106247
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fc8f67d1f7e588fbe1c8e159fa4ace4
https://doi.org/10.1016/j.jsbmb.2023.106247
https://doi.org/10.1016/j.jsbmb.2023.106247