Zobrazeno 1 - 10
of 29 121
pro vyhledávání: '"CARDIOMYOCYTES"'
Autor:
Thomas Hutschalik, Ozan Özgül, Marilù Casini, Brigitta Szabó, Rémi Peyronnet, Óscar Bártulos, Mariana Argenziano, Ulrich Schotten, Elena Matsa
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Background Atrial fibrillation has an estimated prevalence of 1.5–2%, making it the most common cardiac arrhythmia. The processes that cause and sustain the disease are still not completely understood. An association between atrial fibrill
Externí odkaz:
https://doaj.org/article/62230f7377c342b9b213ccfb407b8704
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The compound NS5806 is a Kv4 channel modulator. This study investigated the chronic effects of NS5806 on cardiac hypertrophy induced by transverse aortic constriction (TAC) in mice in vivo and on neonatal rat ventricular cardiomyocyte hypert
Externí odkaz:
https://doaj.org/article/2953d5467b574c2aaa2c089310587c77
Autor:
Bobo Wing-Yee Mok, Maxwell Kwok, Hung Sing Li, Lowell Ling, Angel Lai, Bin Yan, Cherie Tsz-Yiu Law, Chui Him Yeung, Anna Jinxia Zhang, Rachel Chun-Yee Tam, Anja Kukic, Conor J. Cremin, Yajie Zhang, Teng Long, Zhisen Kang, Ruibang Luo, Kam Tong Leung, Albert M. Li, Grace Lui, Stephen Kwok-Wing Tsui, Jasper Fuk-Woo Chan, Kelvin Kai-Wang To, Paul K. S. Chan, Bryan P. Yan, Honglin Chen, Ellen Ngar-Yun Poon
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Background COVID-19 can cause cardiac complications and the latter are associated with poor prognosis and increased mortality. SARS-CoV-2 variants differ in their infectivity and pathogenicity, but how they affect cardiomyocytes (CMs) is unc
Externí odkaz:
https://doaj.org/article/faf07cfdf22342eeb1c12ec8380cea15
Autor:
Jin Ye, Sichi Xu, Xiaoqing Liu, Qiyu Zhang, Xiao Li, Hui Zhang, Jie Ma, Ling Leng, Shuyang Zhang
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Background Abnormalities in T cell activation play an important role in the pathogenesis of myocarditis, and persistent T cell responses can lead to autoimmunity and chronic cardiac inflammation, as well as even dilated cardiomyopathy. Altho
Externí odkaz:
https://doaj.org/article/dcd9961c3e304bae99f1f777cae0d5e7
Autor:
Nils Kriedemann, Felix Manstein, Carlos A. Hernandez-Bautista, Kevin Ullmann, Wiebke Triebert, Annika Franke, Mira Mertens, Inês Carvalheira Arnaut Pombeiro Stein, Andreas Leffler, Merlin Witte, Tamari Askurava, Veronika Fricke, Ina Gruh, Birgit Piep, Kathrin Kowalski, Theresia Kraft, Robert Zweigerdt
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Background Commonly used media for the differentiation of human pluripotent stem cells into cardiomyocytes (hPSC-CMs) contain high concentrations of proteins, in particular albumin, which is prone to quality variations and presents a substan
Externí odkaz:
https://doaj.org/article/c071a733e7104321b7fcea2933e63725
Autor:
Haruka Mori, Dongzhu Xu, Yuzuno Shimoda, Zixun Yuan, Yoshiko Murakata, Binyang Xi, Kimi Sato, Masayoshi Yamamoto, Kazuko Tajiri, Tomoko Ishizu, Masaki Ieda, Nobuyuki Murakoshi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Hypertrophic cardiomyopathy (HCM) is an inherited disorder characterized by left ventricular hypertrophy and diastolic dysfunction, and increases the risk of arrhythmias and heart failure. Some patients with HCM develop a dilated phase of hy
Externí odkaz:
https://doaj.org/article/950a245c40a64329bf3a98ce8a169504
Autor:
Jeffrey Aalders, Laurens Léger, Behrouz Hassannia, Vera Goossens, Tom Vanden Berghe, Jolanda van Hengel
Publikováno v:
Regenerative Therapy, Vol 27, Iss , Pp 21-31 (2024)
Generation of cardiomyocytes from human pluripotent stem cells (hPSCs) is of high interest for disease modelling and regenerative medicine. hPSCs can provide an unlimited source of patient-specific cardiomyocytes that are otherwise difficult to obtai
Externí odkaz:
https://doaj.org/article/560e0a859b58470e9d2823b7cf229719
Autor:
Jin Hee Kim, Jun Hwan Lee
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 27, Iss 6, Pp 755-760 (2024)
Objective(s): MicroRNAs (miRNAs) are small non-coding RNAs that function in all biological processes. Recent findings suggest that exosomes, which are small vesicles abundantly secreted by various cell types, can transport miRNAs to target cells. Her
Externí odkaz:
https://doaj.org/article/a8a324d8699848598d9740f31b5e3ecc