Zobrazeno 1 - 10
of 18
pro vyhledávání: '"CANDELA CIVES-LOSADA"'
Autor:
Jesús Calahorra, José L. Blaya-Cánovas, Olivia Castellini-Pérez, Ernesto Aparicio-Puerta, Candela Cives-Losada, Jose J.G. Marin, Markel Rementeria, Francisca E. Cara, Araceli López-Tejada, Carmen Griñán-Lisón, Francesco Aulicino, Imre Berger, Juan A. Marchal, Violeta Delgado-Almenta, Sergio Granados-Principal
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116439- (2024)
Triple-negative breast cancer (TNBC) is characterised by its aggressiveness and resistance to chemotherapy, demanding the development of effective strategies against its unique characteristics. Derived from lapacho tree bark, β-lapachone (β-LP) sel
Externí odkaz:
https://doaj.org/article/76400c7a3a124b0abb61e19973f4cfab
Autor:
Gabriela Rodríguez-Macías, Oscar Briz, Candela Cives-Losada, María C. Chillón, Carolina Martínez-Laperche, Ibon Martínez-Arranz, Ismael Buño, Marcos González-Díaz, José L. Díez-Martín, Jose J. G. Marin, Rocio I. R. Macias
Publikováno v:
Cancers, Vol 15, Iss 12, p 3145 (2023)
Despite its often low efficacy and high toxicity, the standard treatment for acute myeloid leukemia (AML) is induction chemotherapy with cytarabine and idarubicin. Here, we have investigated the role of transporters and drug-metabolizing enzymes in t
Externí odkaz:
https://doaj.org/article/d81a4d3c21e1449e94bc8099d7a366af
Autor:
Jose J. G. Marin, Maria J. Monte, Rocio I. R. Macias, Marta R. Romero, Elisa Herraez, Maitane Asensio, Sara Ortiz-Rivero, Candela Cives-Losada, Silvia Di Giacomo, Javier Gonzalez-Gallego, Jose L. Mauriz, Thomas Efferth, Oscar Briz
Publikováno v:
Cancers, Vol 14, Iss 14, p 3524 (2022)
Hepatobiliary, pancreatic, and gastrointestinal cancers account for 36% of the ten million deaths caused by cancer worldwide every year. The two main reasons for this high mortality are their late diagnosis and their high refractoriness to pharmacolo
Externí odkaz:
https://doaj.org/article/d9f43514b8954b73a515af64fb664117
Autor:
Jose J. G. Marin, Paula Sanchon-Sanchez, Candela Cives-Losada, Sofía del Carmen, Jesús M. González-Santiago, Maria J. Monte, Rocio I. R. Macias
Publikováno v:
Cancers, Vol 13, Iss 10, p 2358 (2021)
Despite the crucial advances in understanding the biology of cholangiocarcinoma (CCA) achieved during the last decade, very little of this knowledge has been translated into clinical practice. Thus, CCA prognosis is among the most dismal of solid tum
Externí odkaz:
https://doaj.org/article/4d3a132381c340f48b934020b8d46c23
Autor:
Alba M. G. Blazquez, Rocio I. R. Macias, Candela Cives-Losada, Alberto de la Iglesia, Jose J. G. Marin, Maria J. Monte
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Transporters involved in bile acid (BA) handling by the mammary gland are poorly understood. Here we have investigated the role of ABC proteins in blood-milk BA traffic and its sensitivity to maternal cholestasis. BA concentrations in rat an
Externí odkaz:
https://doaj.org/article/7420089d0fcb4fc2bbcafa376e74fce2
Autor:
Jose J. G. Marin, Laura Perez-Silva, Rocio I. R. Macias, Maitane Asensio, Ana Peleteiro-Vigil, Anabel Sanchez-Martin, Candela Cives-Losada, Paula Sanchon-Sanchez, Beatriz Sanchez De Blas, Elisa Herraez, Oscar Briz, Elisa Lozano
Publikováno v:
Cancers, Vol 12, Iss 8, p 2116 (2020)
Gastric adenocarcinoma (GAC) is the most common histological type of gastric cancer, the fifth according to the frequency and the third among the deadliest cancers. GAC high mortality is due to a combination of factors, such as silent evolution, late
Externí odkaz:
https://doaj.org/article/6a434fe4752641f994bacdacceba53f0
Autor:
Jose J.G. Marin, Rocio I.R. Macias, Maria J. Monte, Marta R. Romero, Maitane Asensio, Anabel Sanchez-Martin, Candela Cives-Losada, Alvaro G. Temprano, Ricardo Espinosa-Escudero, Maria Reviejo, Laura H. Bohorquez, Oscar Briz
Publikováno v:
Cancers, Vol 12, Iss 6, p 1663 (2020)
The poor outcome of patients with non-surgically removable advanced hepatocellular carcinoma (HCC), the most frequent type of primary liver cancer, is mainly due to the high refractoriness of this aggressive tumor to classical chemotherapy. Novel pha
Externí odkaz:
https://doaj.org/article/9e7818cd50f947b2bf3eda36316f57fd
Autor:
Jose J.G. Marin, Rocio I.R. Macias, Candela Cives-Losada, Ana Peleteiro-Vigil, Elisa Herraez, Elisa Lozano
Publikováno v:
Cells, Vol 9, Iss 2, p 498 (2020)
The dismal prognosis of patients with advanced cholangiocarcinoma (CCA) is due, in part, to the extreme resistance of this type of liver cancer to available chemotherapeutic agents. Among the complex mechanisms accounting for CCA chemoresistance are
Externí odkaz:
https://doaj.org/article/5939db0de36e49708baab083bd1bef2c
Autor:
Jose J. G. Marin, Candela Cives-Losada, Maitane Asensio, Elisa Lozano, Oscar Briz, Rocio I. R. Macias
Publikováno v:
Cancers, Vol 11, Iss 3, p 407 (2019)
The most frequent liver tumor in children is hepatoblastoma (HB), which derives from embryonic parenchymal liver cells or hepatoblasts. Hepatocellular carcinoma (HCC), which rarely affects young people, causes one fourth of deaths due to cancer in ad
Externí odkaz:
https://doaj.org/article/00254053434041229c199b3519189d43
Autor:
Macias, Gabriela Rodríguez-Macías, Oscar Briz, Candela Cives-Losada, María C. Chillón, Carolina Martínez-Laperche, Ibon Martínez-Arranz, Ismael Buño, Marcos González-Díaz, José L. Díez-Martín, Jose J. G. Marin, Rocio I. R.
Publikováno v:
Cancers; Volume 15; Issue 12; Pages: 3145
Despite its often low efficacy and high toxicity, the standard treatment for acute myeloid leukemia (AML) is induction chemotherapy with cytarabine and idarubicin. Here, we have investigated the role of transporters and drug-metabolizing enzymes in t