Zobrazeno 1 - 10
of 41 270
pro vyhledávání: '"CANCER STEM CELL"'
Autor:
Saba Abedimanesh, Reza Safaralizadeh, Zohreh Jahanafrooz, Souzan Najafi, Mohammad Amini, Shabnam Soltani Nazarloo, Seyedeh Zahra Bahojb Mahdavi, Behzad Baradaran, Asiyeh Jebelli, Amir Ali Mokhtarzadeh
Publikováno v:
Non-coding RNA Research, Vol 9, Iss 4, Pp 1292-1307 (2024)
The Hippo signaling pathway has a regulatory function in the organogenesis process and cellular homeostasis, switching the cascade reactions of crucial kinases acts to turn off/on the Hippo pathway, altering the downstream gene expression and thereby
Externí odkaz:
https://doaj.org/article/1749b5eb4bc84318b10f8f4daecf2ae1
Publikováno v:
IBRO Neuroscience Reports, Vol 17, Iss , Pp 73-82 (2024)
Neuroblastomas are pediatric tumors arising from undifferentiated cells of neural crest origin with stem cell-like characteristics. Dysregulation of Wnt/β-catenin signaling has been shown to be linked to the development of various tumors. Activated
Externí odkaz:
https://doaj.org/article/306a87f63d1a4d5cb607bb23c9bc73ea
Publikováno v:
Cell Regeneration, Vol 13, Iss 1, Pp 1-21 (2024)
Abstract Human stem cells are undifferentiated cells with the capacity for self-renewal and differentiation into distinct cell lineages, playing important role in the development and maintenance of diverse tissues and organs. The microenvironment of
Externí odkaz:
https://doaj.org/article/6fc1371d5f6345d7bceffc106c1d8aaa
Publikováno v:
BMC Gastroenterology, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Gastric cancer stem cells (GCSCs) are key contributors to tumorigenesis, recurrence and metastasis, complicating gastric cancer (GC) treatment. Rhaponticin (RA), a potential novel anticancer drug, has unexplored effects on GCSCs.
Externí odkaz:
https://doaj.org/article/8e9fa2d0dece4743a4b7c7cb8bea8de7
Autor:
So-Hyun Yoon, Sangeun Lee, Hoe Suk Kim, Junhyuk Song, Moonjou Baek, Seungyeon Ryu, Han-Byoel Lee, Hyeong-Gon Moon, Dong-Young Noh, Sangyong Jon, Wonshik Han
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background NAD(P)-dependent steroid dehydrogenase-like protein (NSDHL), which is involved in breast tumor growth and metastasis, has been implicated in the maintenance of cancer stem cells. However, its role in regulating breast cancer stem-
Externí odkaz:
https://doaj.org/article/7db479f810e941bcb9add8110729df41
Autor:
Chenxu Zhu, Thomas Stiehl
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Acute myeloid leukemia (AML) is a stem cell-driven malignancy of the blood forming (hematopoietic) system. Despite of high dose chemotherapy with toxic side effects, many patients eventually relapse. The “7+3 regimen”, which consists of
Externí odkaz:
https://doaj.org/article/8f02ebadfb574c74abf0bc8a013179de
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract The Rho GTPase signaling pathway is responsible for cell-specific processes, including actin cytoskeleton organization, cell motility, cell division, and the transcription of specific genes. The implications of RhoA and the downstream effect
Externí odkaz:
https://doaj.org/article/b34eb8627a054c44a41af5e1628e9554
Autor:
Jing Lu, Ying Zhang, Chunyan Yan, Jingwen Liu, Dan Qi, Yue Zhou, Qinwen Wang, Juechen Yang, Jing Jiang, Benhao Wu, Meiling Yang, Weiwei Zhang, Xin Zhang, Xiaoyu Shi, Yan Zhang, Kun Liu, Yongcai Liang, Chaoyang Wang, Hanyu Yang, Yuqing Gao, Yuping Sun, Ronghu Ke, Jason H. Huang, Min Wu, Hongbo Wang, Chunlei Li, Shuang Zhou, Bin Guo, Erxi Wu, Guoying Zhang
Publikováno v:
Bioactive Materials, Vol 45, Iss , Pp 567-583 (2025)
Despite significant advances in targeted therapies and immunotherapies, non-small cell lung cancer (NSCLC) continues to present a global health challenge, with a modest five-year survival rate of 28 %, largely due to the emergence of treatment-resist
Externí odkaz:
https://doaj.org/article/cff710ae71ab4234b9bdb62630b83ea2
Autor:
Krittiyabhorn Kongtanawanich, Sunisa Prasopporn, Supawan Jamnongsong, Nontaphat Thongsin, Tongchai Payungwong, Seiji Okada, Marianne Hokland, Methichit Wattanapanitch, Siwanon Jirawatnotai
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Cancer stem cells (CSC) play an important role in carcinogenesis and are acknowledged to be responsible for chemoresistance in cholangiocarcinoma (CCA). Studying CCA CSC has been challenging, due to lack of consensus CSC markers, and to thei
Externí odkaz:
https://doaj.org/article/f122727f4db34b84928968f66c334b3a
Autor:
Jie Mu, Ruizhi Li, Yu Zheng, Yi Lu, Lei Ma, Lin Yin, Miao Zhang, Wenyu Ma, Mengjia Chang, Aihua Liu, Jing Li, Hai Zhu, Dong Wang
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Background Intermediate cells are present in the early stages of human prostate development and adenocarcinoma. While primary cells isolated from benign human prostate tissues or tumors exhibit an intermediate phenotype in vitro, they cannot
Externí odkaz:
https://doaj.org/article/91c6e2b653db426688625279c1c5c38c