Zobrazeno 1 - 10
of 102
pro vyhledávání: '"CAMP RECEPTORS"'
Autor:
Yamada, Yoko, Schaap, Pauline
Publikováno v:
Developmental Biology
Dictyostelium discoideum amoebas display colonial multicellularity where starving amoebas aggregate to form migrating slugs and fruiting bodies consisting of spores and three supporting cell types. To resolve the cell signalling mechanism that contro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc35742f169fcc944fb4af26a4316dbf
http://europepmc.org/articles/PMC6598861
http://europepmc.org/articles/PMC6598861
Autor:
William G. Robichaux, Xiaodong Cheng
Publikováno v:
Physiological Reviews
This review focuses on one family of the known cAMP receptors, the exchange proteins directly activated by cAMP (EPACs), also known as the cAMP-regulated guanine nucleotide exchange factors (cAMP-GEFs). Although EPAC proteins are fairly new additions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3936252d5e57087002eaa0059dfdc1da
Publikováno v:
Nature Reviews Molecular Cell Biology, 5(8), 626-634. Nature Publishing Group
Chemotaxis is the result of a refined interplay among various intracellular molecules that process spatial and temporal information. Here we present a modular scheme of the complex interactions between the front and the back of cells that allows them
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffc7e03100c0d8de29a09ed415143ed6
https://doi.org/10.1038/sj.embor.7400051
https://doi.org/10.1038/sj.embor.7400051
Publikováno v:
Biochimica et Biophysica Acta-General Subjects, 1623(2-3), 129-134. ELSEVIER SCIENCE BV
Chemoattractant stimulation of Dictyostelium cells leads to the opening of calcium channels in the plasma membrane, causing extracellular calcium to flux into the cell. The genetically uncharacterised mutants stimF and K18 show strongly altered chemo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db977272bdd7056542cd16799d4f9a9
https://hdl.handle.net/11370/64cbfdb2-fd51-48a8-92b7-ab4a1752fea4
https://hdl.handle.net/11370/64cbfdb2-fd51-48a8-92b7-ab4a1752fea4
Publikováno v:
The Journal of Cell Biology
Journal of Cell Biology, 134(6), 1543-1549. ROCKEFELLER UNIV PRESS
Journal of Cell Biology, 134(6), 1543-1549. ROCKEFELLER UNIV PRESS
Starving Dictyostelium cells aggregate by chemotaxis to cAMP when a secreted protein called conditioned medium factor (CMF) reaches a threshold concentration. Cells expressing CMF antisense mRNA fail to aggregate and do not transduce signals from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4342f2111fd20c0bf5b888beedf9e533
https://doi.org/10.1083/jcb.134.6.1543
https://doi.org/10.1083/jcb.134.6.1543
Autor:
Yimin Yu, Charles L. Saxe
Publikováno v:
Developmental Biology. 173:353-356
Signal transduction via a family of cAMP receptor subtypes (cARs) is critical for proper development in the cellular slime moldDictyostelium.Genes encoding four related subtypes have been cloned and their expression, based on RNA accumulation, has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5977295de11d7c2b7621444462533d6
https://doi.org/10.1006/dbio.1996.0030
https://doi.org/10.1006/dbio.1996.0030
Autor:
van Peter Haastert, Renu Jain, Ita S. Yuen, William J. Deery, David F. Lindsey, John D. Bishop, Richard H. Gomer
Publikováno v:
The Journal of Cell Biology
The Journal of Cell Biology, 129(5), 1251-1262. ROCKEFELLER UNIV PRESS
The Journal of Cell Biology, 129(5), 1251-1262. ROCKEFELLER UNIV PRESS
Dictyostelium discoideum initiates development when cells overgrow their bacterial food source and starve. To coordinate development, the cells monitor the extracellular level of a protein, conditioned medium factor (CMF), secreted by starved cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6b84ca5e7510df9bc2e2352cef0031
https://research.rug.nl/en/publications/13399145-76f8-4cb9-b634-dcd28eccd8ac
https://research.rug.nl/en/publications/13399145-76f8-4cb9-b634-dcd28eccd8ac
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30441 (2012)
PLoS ONE
PLoS ONE
Background The discovery, more than ten years ago, of exchange proteins directly activated by cAMP (EPAC) as a new family of intracellular cAMP receptors revolutionized the cAMP signaling research field. Extensive studies have revealed that the cAMP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e22fcc479168fd86fc172a2498a58f6
http://europepmc.org/articles/PMC3262007?pdf=render
http://europepmc.org/articles/PMC3262007?pdf=render
Publikováno v:
Biochemical Journal. 303:539-545
Dictyostelium discoideum cells contain cell surface cyclic AMP (cAMP) receptors that bind cAMP as a first messenger and intracellular cAMP receptors that bind cAMP as a second messenger. Prolonged incubation of Dictyostelium cells with cAMP induces a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dris___01423::59a8b9c136d02629fe73348b4b1037b8
https://research.rug.nl/en/publications/86e9277c-b743-4a0e-a58b-cacd6da6098b
https://research.rug.nl/en/publications/86e9277c-b743-4a0e-a58b-cacd6da6098b
Publikováno v:
The EMBO Journal. 13(7):1601-1609
The micro-organism Dictyostelium uses extracellular cAMP to induce chemotaxis and cell differentiation. Signals are transduced via surface receptors, which activate G proteins, to effector enzymes. The deduced protein sequence of Dictyostelium discoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dris___01423::215472bcc70fddc84f4aca0e1814e78b
https://research.rug.nl/en/publications/bc50ac4b-05ec-4534-9fdf-a9020520d785
https://research.rug.nl/en/publications/bc50ac4b-05ec-4534-9fdf-a9020520d785