Receptor-mediated targeted drug delivery systems for treatment of inflammatory bowel disease: Opportunities and emerging strategies

Autor: Caifang Gao, Peng Liu, Hongguo Chen, Xu Wu, Xudong Tang, Yitao Wang, Chi Teng Vong, Shengpeng Wang

Publikováno v: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2798-2818 (2021)

Inflammatory bowel disease (IBD) is a chronic intestinal disease with painful clinical manifestations and high risks of cancerization. With no curative therapy for IBD at present, the development of effective therapeutics is highly advocated. Drug de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf33f667c4f81b143c5ccef5cfb99fc
http://europepmc.org/articles/PMC8463263

Structure of the Tandem Fibronectin Type 3 Domains of Neural Cell Adhesion Molecule

Autor: Federico Carafoli, Jane L. Saffell, Erhard Hohenester

Publikováno v: Journal of Molecular Biology

Activation of the fibroblast growth factor receptor (FGFR) by neural cell adhesion molecule (NCAM) is essential for NCAM-mediated neurite outgrowth. Previous peptide studies have identified two regions in the fibronectin type 3 (FN3)-like domains of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::052779eb64f41f85e25bff76534e6ded
https://doi.org/10.1016/j.jmb.2008.01.030

Tumour Necrosis Factor α Enhances CCL2 and ICAM-1 Expression in Peripheral Nerve Microvascular Endoneurial Endothelial Cells

Autor: Kelly A. Langert, Evan B. Stubbs, Cynthia L. Von Zee

Publikováno v: ASN Neuro, Vol 5 (2013)
ASN NEURO

Recruitment and trafficking of autoreactive leucocytes across the BNB (blood–nerve barrier) is an early pathological insult in GBS (Guillain-Barré syndrome), an aggressive autoimmune disorder of the PNS (peripheral nervous system). Whereas the aet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed343e8835617477143d5cf790b19249
https://doaj.org/article/424a5970b09044c0a56bca24b2237e90

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The impact of SELP gene Thr715Pro polymorphism on sP-selectin level and association with cardiovascular disease in Saudi diabetic patients: A cross-sectional case-control study.

Autor: Alzahrani FM; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University. P.O.Box 1982, Dammam 31441, Saudi Arabia., Alhassan JA; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University. P.O.Box 1982, Dammam 31441, Saudi Arabia., Alshehri AM; Department of Medicine, College of Medicine, Imam Abdulrahman Bin Faisal University, P.O.Box 1982, Dammam 31441, Saudi Arabia., Farooqi FA; College of dentistry, Imam Abdulrahman Bin Faisal University, P.O.Box 1982, Dammam 31441, Saudi Arabia., Aldossary MA; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University. P.O.Box 1982, Dammam 31441, Saudi Arabia., Abdelghany MK; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University. P.O.Box 1982, Dammam 31441, Saudi Arabia., Ibrahim H; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University. P.O.Box 1982, Dammam 31441, Saudi Arabia., El-Masry OS; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University. P.O.Box 1982, Dammam 31441, Saudi Arabia.

Publikováno v: Saudi journal of biological sciences [Saudi J Biol Sci] 2023 Mar; Vol. 30 (3), pp. 103579. Date of Electronic Publication: 2023 Feb 02.