REVEALING HIDDEN PATTERNS: HOW UNSUPERVISED MACHINE LEARNING AND MCA PREDICT SURVIVAL IN NODAL PERIPHERAL T-CELL LYMPHOMA PATIENTS

Autor: CO Reichert, G Carneiro, HF Culler, FA Freitas, VG Rocha, CA Murga-Zamalloa, LAPC Lage, R Olimpio, J Pereira

Publikováno v: Hematology, Transfusion and Cell Therapy, Vol 46, Iss , Pp S259-S260 (2024)

Unsupervised machine learning techniques are employed to understand patterns and behaviors of variables in databases. Multiple Correspondence Analysis (MCA), an extension of correspondence analysis, can be used to verify the association of categorica

Externí odkaz: https://doaj.org/article/09e511cd9584476d9c4c4e46373b1198

Reduced bioenergetics and mitochondrial fragmentation in human primary cytotrophoblasts induced by an EGFR-targeting chemical mixture.

Autor: Waye AA; Department of Pathology, University of Illinois Chicago, Chicago, IL, USA., Ticiani E; Department of Pathology, University of Illinois Chicago, Chicago, IL, USA., Sharmin Z; Department of Pathology, University of Illinois Chicago, Chicago, IL, USA., Perez Silos V; Department of Pathology, University of Illinois Chicago, Chicago, IL, USA., Perera T; Department of Chemistry, University of Illinois Chicago, Chicago, IL, USA., Tu A; Department of Chemistry, University of Illinois Chicago, Chicago, IL, USA., Buhimschi IA; Department of Obstetrics & Gynecology, University of Illinois Chicago, Chicago, IL, USA., Murga-Zamalloa CA; Department of Pathology, University of Illinois Chicago, Chicago, IL, USA., Hu YS; Department of Chemistry, University of Illinois Chicago, Chicago, IL, USA., Veiga-Lopez A; Department of Pathology, University of Illinois Chicago, Chicago, IL, USA; The Chicago Center for Health and Environment, University of Illinois Chicago, Chicago, IL, USA. Electronic address: veiga@uic.edu.

Publikováno v: Chemosphere [Chemosphere] 2024 Sep; Vol. 364, pp. 143301. Date of Electronic Publication: 2024 Sep 07.

B-cell lymphoma-2 downregulation is a useful feature supporting a neoplastic phenotype in mature T-cell lymphomas.

Autor: Siddiqui F; The University of Chicago Medicine, Departments of Pathology, Section of Hematopathology, USA., Perez Silos V; Department of Pathology, University of Illinois in Chicago, USA., Karube K; Department of Pathology and Cell Biology, University of the Ryukyus, Okinawa, Japan., Yasin Goksu S; Department of Pathology, University of Illinois in Chicago, USA., Nandakumar S; School of Aeronautics and Astronautics, Purdue University, IN, USA., Saygin C; The University of Chicago Medicine, Departments of Medicine, Section of Hematology/Oncology, USA., Onajin O; The University of Chicago Medicine, Departments of Dermatology, USA., Prabu SS; MS3, Kilpauk Medical College, Chennai, India., Gurbuxani S; The University of Chicago Medicine, Departments of Pathology, Section of Hematopathology, USA., Arber DA; The University of Chicago Medicine, Departments of Pathology, Section of Hematopathology, USA., Tjota M; The University of Chicago Medicine, Departments of Pathology, Section of Hematopathology, USA., Segal J; The University of Chicago Medicine, Departments of Pathology, Section of Hematopathology, USA., Smith SM; The University of Chicago Medicine, Departments of Medicine, Section of Hematology/Oncology, USA., Murga-Zamalloa CA; Department of Pathology, University of Illinois in Chicago, USA., Venkataraman G; The University of Chicago Medicine, Departments of Pathology, Section of Hematopathology, USA. Electronic address: girish.venkataraman@uchospitals.edu.

Publikováno v: Human pathology [Hum Pathol] 2022 Jul; Vol. 125, pp. 48-58. Date of Electronic Publication: 2022 Apr 19.

Multispecies study: low-dose tributyltin impairs ovarian theca cell cholesterol homeostasis through the RXR pathway in five mammalian species including humans.

Autor: Pu Y; Department of Animal Science, Michigan State University, 474 S. Shaw Lane, Room 1230F, East Lansing, MI, 48824, USA., Pearl S; Sparrow Hospital, Lansing, MI, USA., Gingrich J; Department of Animal Science, Michigan State University, 474 S. Shaw Lane, Room 1230F, East Lansing, MI, 48824, USA.; Department of Pharmacology and Toxicology, Michigan State University, East Lansing, MI, USA., Jing J; Department of Animal Science, Michigan State University, 474 S. Shaw Lane, Room 1230F, East Lansing, MI, 48824, USA., Martin D; Sparrow Hospital, Lansing, MI, USA., Murga-Zamalloa CA; Division of Hematology and Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Veiga-Lopez A; Department of Animal Science, Michigan State University, 474 S. Shaw Lane, Room 1230F, East Lansing, MI, 48824, USA. veiga@msu.edu.

Publikováno v: Archives of toxicology [Arch Toxicol] 2019 Jun; Vol. 93 (6), pp. 1665-1677. Date of Electronic Publication: 2019 Apr 21.

NPM-ALK phosphorylates WASp Y102 and contributes to oncogenesis of anaplastic large cell lymphoma.

Autor: Murga-Zamalloa CA; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Mendoza-Reinoso V; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Sahasrabuddhe AA; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Rolland D; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA., Hwang SR; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., McDonnell SR; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Sciallis AP; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Wilcox RA; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Bashur V; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Elenitoba-Johnson K; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA., Lim MS; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Publikováno v: Oncogene [Oncogene] 2017 Apr; Vol. 36 (15), pp. 2085-2094. Date of Electronic Publication: 2016 Oct 03.