Zobrazeno 1 - 10
of 62
pro vyhledávání: '"C700 Molecular Biology, Biophysics and Biochemistry"'
Autor:
Cowley, David, Deinert, JP
This is a scientific literature review of a large selection of studies drawn from medical research publications databases, including PubMed, bioRxiv and ResearchGate. Its particular focus concerns the therapeutic benefits and mode of action of baical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f419924fa276e55239eaa234f1c20957
Publikováno v:
European Journal of Applied Physiology
Objective Pulmonary rehabilitation is a cornerstone treatment in the management of chronic obstructive pulmonary disease (COPD). Acute bouts of exercise can lead to short bursts of inflammation in healthy individuals. However, it is unclear how COPD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f3b777140d9cb9555f7d1690f81203f
https://doi.org/10.1007/s00421-020-04452-z
https://doi.org/10.1007/s00421-020-04452-z
Publikováno v:
The Journal of Antibiotics
The Gram-positive bacterium Streptococcus pneumoniae is one of the common causes of community acquired pneumonia, meningitis, and otitis media. Analyzing the metabolic adaptation toward environmental stress conditions improves our understanding of it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e64228bfbe7af5c5ada9ba526d761437
https://doi.org/10.1038/s41429-020-0296-3
https://doi.org/10.1038/s41429-020-0296-3
Mitochondria is a unique cellular organelle involved in multiple cellular processes and is critical for maintaining cellular homeostasis. This semi-autonomous organelle contains its circular genome - mtDNA (mitochondrial DNA), that undergoes continuo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13431c4c9bafd58ba6606cb94166abac
https://eprints.lincoln.ac.uk/id/eprint/48716/1/1-s2.0-S0005272822000238-main.pdf
https://eprints.lincoln.ac.uk/id/eprint/48716/1/1-s2.0-S0005272822000238-main.pdf
Publikováno v:
Genes
Andrews, W J, Ray, S, Panova, T, Engel, C & Panov, K I 2021, ' DNA Intercalators Inhibit Eukaryotic Ribosomal RNA Synthesis by Impairing the Initiation of Transcription ', Genes, vol. 12, no. 9, 1412 . https://doi.org/10.3390/genes12091412
Volume 12
Issue 9
Genes, Vol 12, Iss 1412, p 1412 (2021)
Andrews, W J, Ray, S, Panova, T, Engel, C & Panov, K I 2021, ' DNA Intercalators Inhibit Eukaryotic Ribosomal RNA Synthesis by Impairing the Initiation of Transcription ', Genes, vol. 12, no. 9, 1412 . https://doi.org/10.3390/genes12091412
Volume 12
Issue 9
Genes, Vol 12, Iss 1412, p 1412 (2021)
In eukaryotes, ribosome biogenesis is driven by the synthesis of the ribosomal RNA (rRNA) by RNA polymerase I (Pol-I) and is tightly linked to cell growth and proliferation. The 3D-structure of the rDNA promoter plays an important, yet not fully unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab0c43edf06de14c763baf58b819c420
http://europepmc.org/articles/PMC8466728
http://europepmc.org/articles/PMC8466728
Autor:
Evangelia Karyka, Nelly Berrueta Ramirez, Christopher P Webster, Paolo M Marchi, Emily J Graves, Vinay K Godena, Lara Marrone, Anushka Bhargava, Swagat Ray, Ke Ning, Hannah Crane, Guillaume M Hautbergue, Sherif F El-Khamisy, Mimoun Azzouz
Publikováno v:
Life science alliance. 5(8)
Spinal muscular atrophy, the leading genetic cause of infant mortality, is a motor neuron disease caused by low levels of survival motor neuron (SMN) protein. SMN is a multifunctional protein that is implicated in numerous cytoplasmic and nuclear pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3d46e398b54386c1303922357ff4aa0
https://pubmed.ncbi.nlm.nih.gov/35440492
https://pubmed.ncbi.nlm.nih.gov/35440492
Autor:
Claire E. Hills, Wai Han Yiu, Gareth Price, Colin R. Green, Christos E. Chadjichristos, Joe A. Potter, Eleftherios Siamantouras, Sydney C.W. Tang, Panagiotis Kavvadas, Paul E. Squires
Publikováno v:
Cell Communication and Signaling : CCS
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-17 (2020)
Cell Communication and Signaling
Cell Communication and Signaling, BioMed Central, 2020, 18 (1), pp.79. ⟨10.1186/s12964-020-00558-1⟩
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-17 (2020)
Cell Communication and Signaling
Cell Communication and Signaling, BioMed Central, 2020, 18 (1), pp.79. ⟨10.1186/s12964-020-00558-1⟩
Background Tubulointerstitial fibrosis represents the key underlying pathology of Chronic Kidney Disease (CKD), yet treatment options remain limited. In this study, we investigated the role of connexin43 (Cx43) hemichannel-mediated adenosine triphosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe13882cb5a152cf3cdbc758fabea8ab
http://europepmc.org/articles/PMC7249671
http://europepmc.org/articles/PMC7249671
Publikováno v:
Biomaterials science. 8(9)
Dedicated chemistries for on-demand capture and release of biomolecules at the solid–liquid interface are required for applications in drug delivery, for the synthesis of switchable surfaces used in analytical devices and for the assembly of next-g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eab35e344c9a69b4ef3dc2453c7a2f9
https://pubmed.ncbi.nlm.nih.gov/32254844
https://pubmed.ncbi.nlm.nih.gov/32254844
Autor:
Martínez-Lumbreras, Santiago, Krysztofinska, Ewelina M., Thapaliya, Arjun, Spilotros, Alessandro, Matak-Vinkovic, Dijana, Salvadori, Enrico, Roboti, Peristera, Nyathi, Yvonne, Muench, Janina H., Roessler, Maxie M., Svergun, Dmitri I., High, Stephen, Isaacson, Rivka L.
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-18 (2018)
BMC biology 16(1), 76 (2018). doi:10.1186/s12915-018-0542-3
Martínez-lumbreras, S, Krysztofinska, E M, Thapaliya, A, Spilotros, A, Matak-vinkovic, D, Salvadori, E, Roboti, P, Nyathi, Y, Muench, J H, Roessler, M M, Svergun, D I, High, S & Isaacson, R L 2018, ' Structural complexity of the co-chaperone SGTA: a conserved C-terminal region is implicated in dimerization and substrate quality control ', BMC Biology, vol. 16, no. 1 . https://doi.org/10.1186/s12915-018-0542-3
Martínez-Lumbreras, S, Krysztofinska, E M, Thapaliya, A, Spilotros, A, Matak-Vinkovic, D, Salvadori, E, Roboti, P, Nyathi, Y, Muench, J H, Roessler, M M, Svergun, D I, High, S & Isaacson, R L 2018, ' Structural complexity of the co-chaperone SGTA : a conserved C-terminal region is implicated in dimerization and substrate quality control ', BMC Biology, vol. 16, no. 1, 76 . https://doi.org/10.1186/s12915-018-0542-3
BMC Biology
BMC biology 16(1), 76 (2018). doi:10.1186/s12915-018-0542-3
Martínez-lumbreras, S, Krysztofinska, E M, Thapaliya, A, Spilotros, A, Matak-vinkovic, D, Salvadori, E, Roboti, P, Nyathi, Y, Muench, J H, Roessler, M M, Svergun, D I, High, S & Isaacson, R L 2018, ' Structural complexity of the co-chaperone SGTA: a conserved C-terminal region is implicated in dimerization and substrate quality control ', BMC Biology, vol. 16, no. 1 . https://doi.org/10.1186/s12915-018-0542-3
Martínez-Lumbreras, S, Krysztofinska, E M, Thapaliya, A, Spilotros, A, Matak-Vinkovic, D, Salvadori, E, Roboti, P, Nyathi, Y, Muench, J H, Roessler, M M, Svergun, D I, High, S & Isaacson, R L 2018, ' Structural complexity of the co-chaperone SGTA : a conserved C-terminal region is implicated in dimerization and substrate quality control ', BMC Biology, vol. 16, no. 1, 76 . https://doi.org/10.1186/s12915-018-0542-3
BMC Biology
BMC biology 16(1), 76 (2018). doi:10.1186/s12915-018-0542-3
Protein quality control mechanisms are essential for cell health and involve delivery of proteins to specific cellular compartments for recycling or degradation. In particular, stray hy
Protein quality control mechanisms are essential for cell health and involve delivery of proteins to specific cellular compartments for recycling or degradation. In particular, stray hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a81ab1361cec255d34e2da71d20d144d
http://link.springer.com/article/10.1186/s12915-018-0542-3
http://link.springer.com/article/10.1186/s12915-018-0542-3
Autor:
Cara K. Vaughan, Konstantinos Thalassinos, Wenjuan Zhang, Richard A. Kerr, Oliver Willhoft, Tina Daviter, Caezar Al-Jassar, Dipali Patel, Stefan H. Millson
Publikováno v:
Scientific Reports
The essential cochaperone Sgt1 recruits Hsp90 chaperone activity to a range of cellular factors including SCF E3 ubiquitin ligases and the kinetochore in eukaryotes. In these pathways Sgt1 interacts with Skp1, a small protein that heterodimerizes wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1262e274222a4fc72da240fcae255a5
https://eprints.lincoln.ac.uk/id/eprint/25968/1/Willhoft_et_al-2017-Scientific_Reports.pdf
https://eprints.lincoln.ac.uk/id/eprint/25968/1/Willhoft_et_al-2017-Scientific_Reports.pdf