Zobrazeno 1 - 10
of 1 714
pro vyhledávání: '"C5A RECEPTOR"'
Autor:
Carl Vahldieck, Samuel Löning, Constantin Hamacher, Benedikt Fels, Bettina Rudzewski, Laura Nickel, Joachim Weil, Henry Nording, Lasse Baron, Marie Kleingarn, Christian Marcel Karsten, Kristina Kusche-Vihrog
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionComplement-mediated damage to the myocardium during acute myocardial infarction (AMI), particularly the late components of the terminal pathway (C5-convertase and C5b-9), have previously been characterized. Unfortunately, only few studies
Externí odkaz:
https://doaj.org/article/75024daf9ab14d91aa5ffd07a52ea2c8
Autor:
Hsiao-Jou Cortina Chen, Jereme G. Spiers, Titaya Lerskiatiphanich, Sandra E. Parker, Nickolas A. Lavidis, Jenny N. Fung, Trent M. Woodruff, John D. Lee
Publikováno v:
Biological Psychiatry Global Open Science, Vol 4, Iss 3, Pp 100306- (2024)
Background: Accumulating evidence underscores the pivotal role of heightened inflammation in the pathophysiology of stress-related diseases, but the underlying mechanisms remain elusive. The complement system, a key effector of the innate immune syst
Externí odkaz:
https://doaj.org/article/1dd1912f28f94e758319c69b9a634afc
Autor:
Ziqi Gan, Zecong Xiao, Zhen Zhang, Yang Li, Chao Liu, Xin Chen, Yuanbo Liu, Dongle Wu, Chufeng Liu, Xintao Shuai, Yang Cao
Publikováno v:
Bioactive Materials, Vol 25, Iss , Pp 347-359 (2023)
Periodontitis is admittedly a microbe-driven intractable infectious disease, in which Porphyromonas gingivalis (Pg) plays a keystone role. Pg can selectively impair the antimicrobial responses of periodontal resident macrophages including their phago
Externí odkaz:
https://doaj.org/article/b75086cfccec4b51bb1b4efeecf5a124
Akademický článek
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Publikováno v:
Journal of Education, Health and Sport, Vol 12, Iss 8 (2022)
Objective: This study aimed to evaluate the role of the complement system in a therapy of the ANCA- associated vasculitis. Methods and materials: A literature search was conducted in the PubMed MEADLINE database of medical publications using the
Externí odkaz:
https://doaj.org/article/b68f52ea737b421baa6a6fbd8a195e42
Autor:
Eleni Fella, Revekka Papacharalambous, Demos Kynigopoulos, Maria Ioannou, Rita Derua, Christiana Christodoulou, Myrto Stylianou, Christos Karaiskos, Alexia Kagiava, Gerasimou Petroula, Chryso Pierides, Maria Kyriakou, Laura Koumas, Paul Costeas, Elena Panayiotou
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Alzheimer’s disease (AD) is a progressive neurodegenerative disease of the brain causing either familial or sporadic dementia. We have previously administered the modified C5a receptor agonist (EP67) for a short period to a transgenic mouse model o
Externí odkaz:
https://doaj.org/article/4c05962d56b94ee2831beb46d9c96d5e
Akademický článek
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Autor:
Peng Zhang, Wen‐Wei Yu, Jing Peng, Liang‐Fei Xu, Chang‐Cheng Zhao, Wen‐Jiao Chang, Xiao‐Ling Ma
Publikováno v:
Cancer Medicine, Vol 8, Iss 5, Pp 2474-2483 (2019)
Abstract LukS‐PV is one of the two components of Panton‐Valentine leucocidin (PVL). Our previous study showed that LukS‐PV can induce apoptosis in human acute myeloid leukemia (AML) THP‐1 and HL‐60 cells. C5aR (C5a receptor) is the receptor
Externí odkaz:
https://doaj.org/article/6f73924c89c644feb86cbfcc27053b5e
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108995- (2021)
Summary: The complement fragment C5a is closely associated with adaptive immune induction in the mucosa. However, the mechanisms that control CD8+ T cell responses by C5a have not been extensively explored. This study reveals that C5/C5a in the Peyer
Externí odkaz:
https://doaj.org/article/5f23e7572e2d47059ef7593337373246
Akademický článek
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