Molecular aspects of hereditary complement component C5 deficiency in humans.

Autor: Szymańska, Hanna¹ hanna.szymanska@uwm.edu.pl

Publikováno v: Polish Annals of Medicine. Oct2024, Vol. 31 Issue 2, p1-6. 6p.

Complement Component 5 (C5) Deficiency Improves Cognitive Outcome After Traumatic Brain Injury and Enhances Treatment Effects of Complement Inhibitors C1-Inh and CR2-Crry in a Mouse Model

Autor: Min Chen, Stephen R. Edwards, Dhiraj Maskey, Trent M. Woodruff, Stephen Tomlinson, David Reutens

Publikováno v: Neurotrauma Reports, Vol 4, Iss 1, Pp 663-681 (2023)

A potent effector of innate immunity, the complement system contributes significantly to the pathophysiology of traumatic brain injury (TBI). This study investigated the role of the complement cascade in neurobehavioral outcomes and neuropathology af

Externí odkaz: https://doaj.org/article/2ede2200b0034b69a923faab41e8b79f

The Different Responsiveness of C3- and C5-deficient Murine BM Cells to Oxidative Stress Explains Why C3 Deficiency, in Contrast to C5 Deficiency, Correlates with Better Pharmacological Mobilization and Engraftment of Hematopoietic Cells.

Autor: Konopko A; Center for Preclinical Studies and Technology, Laboratory of Regenerative Medicine at Medical University of Warsaw, Warsaw, Poland. Adrian.konopko@wum.edu.pl., Łukomska A; Center for Preclinical Studies and Technology, Laboratory of Regenerative Medicine at Medical University of Warsaw, Warsaw, Poland., Kucia M; Center for Preclinical Studies and Technology, Laboratory of Regenerative Medicine at Medical University of Warsaw, Warsaw, Poland., Ratajczak MZ; Center for Preclinical Studies and Technology, Laboratory of Regenerative Medicine at Medical University of Warsaw, Warsaw, Poland. mzrata01@louisville.edu.; Stem Cell Institute at James Graham Brown Cancer Center, University of Louisville, 500 S. Floyd Street, Rm. 107, Louisville, KY, 40202, USA. mzrata01@louisville.edu.

Publikováno v: Stem cell reviews and reports [Stem Cell Rev Rep] 2024 Sep 28. Date of Electronic Publication: 2024 Sep 28.

Molecular characterization of three new mutations causing C5 deficiency in two non-related families

Autor: López-Lera, Alberto, Garrido, Sofía, de la Cruz, Rocío Mena, Fontán, Gumersindo, López-Trascasa, Margarita

Publikováno v: In Molecular Immunology 2009 46(11):2340-2347

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