Interaction of MLE with CLAMP zinc finger is involved in proper MSL proteins binding to chromosomes in Drosophila

Autor: Evgeniya Tikhonova, Anastasia Revel-Muroz, Pavel Georgiev, Oksana Maksimenko

Publikováno v: Open Biology, Vol 14, Iss 3 (2024)

The Drosophila male-specific lethal (MSL) complex binds to the male X chromosome to activate transcription. It comprises five proteins (MSL1, MSL2, MSL3, male absent on the first (MOF), and maleless (MLE)) and two long noncoding RNAs (lncRNAs; roX1 a

Externí odkaz: https://doaj.org/article/d2a833f2ebfa4eae8cf6a9d90315013c

Mechanisms of enhancer-promoter communication and chromosomal architecture in mammals and Drosophila

Autor: Olga V. Kyrchanova, Oleg V. Bylino, Pavel G. Georgiev

Publikováno v: Frontiers in Genetics, Vol 13 (2022)

The spatial organization of chromosomes is involved in regulating the majority of intranuclear processes in higher eukaryotes, including gene expression. Drosophila was used as a model to discover many transcription factors whose homologs play a key

Externí odkaz: https://doaj.org/article/2ee893c13a164c8a96bd8c16d80fa268

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Mechanisms of CP190 Interaction with Architectural Proteins in Drosophila Melanogaster

Autor: Anastasia Popovich, Marat Sabirov, Vladimir Popov, Oksana Maksimenko, Artem Bonchuk, Konstantin M. Boyko, Alena Yu. Nikolaeva, Olga Kyrchanova, Pavel Georgiev

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 12400, p 12400 (2021)
Volume 22
Issue 22

Most of the known Drosophila architectural proteins interact with an important cofactor, CP190, that contains three domains (BTB, M, and D) that are involved in protein–protein interactions. The highly conserved N-terminal CP190 BTB domain forms a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daf65fd93a60cab123dd085532d5a235
https://pubmed.ncbi.nlm.nih.gov/34830280