Zobrazeno 1 - 10
of 193
pro vyhledávání: '"C1GALT1"'
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 56, Pp 1108-1117 (2024)
Protein glycosylation is a type of protein post-translational modification. One specific example is the modification of proteins with O-linked β-N-acetylglucosamine (O-GlcNAc) and O-linked α-N-acetylgalactosamine (O-GalNAc). Enhanced levels of both
Externí odkaz:
https://doaj.org/article/13db7865abf24c50a5235741e17972ce
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e31778- (2024)
Core 1 β 1,3-galactosyltransferase 1 (C1GALT1) acts as an important glycosyltransferase in the occurrence and development of tumor glycosylation. However, the regulatory mechanisms of C1GALT1 in thyroid cancer (TC) is still unclear. In this study, w
Externí odkaz:
https://doaj.org/article/b34eb8e0ec634d499a268100c6687b0f
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
C1GALT1 plays a pivotal role in colorectal cancer (CRC) development and progression through its involvement in various molecular mechanisms. This enzyme is central to the O-glycosylation process, producing tumor-associated carbohydrate antigens (TACA
Externí odkaz:
https://doaj.org/article/e50519e270244247968b98885c1303f8
Akademický článek
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Autor:
Zengqi Tan, Yazhuo Jiang, Liang Liang, Jinpeng Wu, Lin Cao, Xiaoman Zhou, Zhihui Song, Zhenyu Ye, Ziyan Zhao, Hui Feng, Zewen Dong, Shuai Lin, Zhangjian Zhou, Yili Wang, Xiang Li, Feng Guan
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-18 (2022)
Abstract Background Abnormal glycosylation in a variety of cancer types is involved in tumor progression and chemoresistance. Glycosyltransferase C1GALT1, the key enzyme in conversion of Tn antigen to T antigen, is involved in both physiological and
Externí odkaz:
https://doaj.org/article/4e1188ad62dc47c1848af28e129b44cc
Autor:
Jiajun Yang, Mengqi Yin, Yao Hou, Hao Li, Yonghong Guo, Hanjie Yu, Kun Zhang, Chen Zhang, Liyuan Jia, Fan Zhang, Xia Li, Huijie Bian, Zheng Li
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Background Ammonia is the most typical neurotoxin in hepatic encephalopathy (HE), but the underlying pathophysiology between ammonia and aberrant glycosylation in HE remains unknown. Results Here, we used HBV transgenic mice and astrocytes t
Externí odkaz:
https://doaj.org/article/4b55e2492b4e4f52b28553893477c4d0
Akademický článek
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Autor:
Xiaoxia Dong, Chunli Chen, Xinzhou Deng, Yongyu Liu, Qiwen Duan, Zhen Peng, Zhiguo Luo, Li Shen
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Background Gastric cancer (GC) is a highly aggressive and lethal disease around the world. High expression of core 1 β 1, 3-galactosyltransferase 1 (C1GALT1), the primary enzyme responsible for protein O-glycosylation, plays a critical role
Externí odkaz:
https://doaj.org/article/0e00affc81a5467391b272b86e374365
Autor:
Yue Xing, Lina Li, Yaru Zhang, Fanghao Wang, Dandan He, Youxia Liu, Junya Jia, Tiekun Yan, Shan Lin
Publikováno v:
BMC Nephrology, Vol 21, Iss 1, Pp 1-9 (2020)
Abstract Background More and more studies demonstrated that genetic variation at C1GALT1 influences Gd-IgA1 level in IgAN. However, whether the expression of β1, 3-galactosyltransferase (β1, 3Gal-T) was influenced may provide insights into how Gd-I
Externí odkaz:
https://doaj.org/article/5130b56050e14e0eaad77b8bfeaefaa8
Akademický článek
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