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Publikováno v:
BIOCELL. 46:937-940
Changes in cell-cell and cell-substrate adhesion markers are increasingly used to characterize disease onset and progression. However, these relationships depend on both the biochemical and molecular association between cells and between cells and th
Introduction: Fibrosis of renal tubules is the final common pathway in diabetic nephropathy and develops in the face of tubular injury and fibroblast activation. Aberrant connexin 43 (Cx43) hemichannel activity has been linked to this damage under eu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79dc3ce717fc7d82e8e9cf44873810d5
The folding of the myosin head often requires a UCS (Unc45, Cro1, She4) domain-containing chaperone. Worms, flies, and fungi have just a single UCS protein. Vertebrates have two; one (Unc45A) which functions primarily in non-muscle cells and another
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e7dea894a6e8b3d8961bcc8663a0ce4
https://eprints.lincoln.ac.uk/id/eprint/50319/1/biomolecules-12-01028.pdf
https://eprints.lincoln.ac.uk/id/eprint/50319/1/biomolecules-12-01028.pdf
Myosin VI is the only minus-end actin motor and is coupled to various cellular processes ranging from endocytosis to transcription. This multi-potent nature is achieved through alternative isoform splicing and interactions with a network of binding p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14d2b4a001a2a2ee2d28765c3aa0c04f
https://eprints.whiterose.ac.uk/188995/1/bcj-2022-0025.pdf
https://eprints.whiterose.ac.uk/188995/1/bcj-2022-0025.pdf
The NOD-like receptor protein 3 (NLRP3) inflammasome is a multi-protein signalling complex integral to the chronic inflammatory response, activated in response to sterile and non-sterile cellular damage. The assembly and activation of the NLRP3 infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cde8a173f75da4dfd55bbed79601cdee
https://eprints.lincoln.ac.uk/id/eprint/49742/1/fphys-13-907504.pdf
https://eprints.lincoln.ac.uk/id/eprint/49742/1/fphys-13-907504.pdf
Autor:
Angelica Varesi, Adelaide Carrara, Vitor Gomes Pires, Valentina Floris, Elisa Pierella, Gabriele Savioli, Sakshi Prasad, Ciro Esposito, Giovanni Ricevuti, Salvatore Chirumbolo, Alessia Pascale
Publikováno v:
Cells
Alzheimer’s Disease (AD) is a progressive neurodegenerative disease characterized by amyloid-β (Aβ) plaque deposition and neurofibrillary tangle accumulation in the brain. Although several studies have been conducted to unravel the complex and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7c0ee1eb7d0639c859fc23604280aaa
https://clok.uclan.ac.uk/41636/1/cells-11-01367.pdf
https://clok.uclan.ac.uk/41636/1/cells-11-01367.pdf
Autor:
Yukti Hari-Gupta, Natalia Fili, Ália dos Santos, Alexander W. Cook, Rosemarie E. Gough, Hannah C. W. Reed, Lin Wang, Jesse Aaron, Tomas Venit, Eric Wait, Andreas Grosse-Berkenbusch, J. Christof M. Gebhardt, Piergiorgio Percipalle, Teng-Leong Chew, Marisa Martin-Fernandez, Christopher P. Toseland
Publikováno v:
Nature Communications
During transcription, RNA Polymerase II (RNAPII) is spatially organised within the nucleus into clusters that correlate with transcription activity. While this is a hallmark of genome regulation in mammalian cells, the mechanisms concerning the assem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcd3d3951e02319a58b110b738eee398
https://eprints.lincoln.ac.uk/id/eprint/49719/1/s41467-022-28962-w.pdf
https://eprints.lincoln.ac.uk/id/eprint/49719/1/s41467-022-28962-w.pdf
Publikováno v:
Cell stresschaperones. 27(3)
In yeast, the Slt2(Mpk1) stress-activated protein kinase directs the activation of two transcription factors, Rlm1 and Swi4/Swi6, in response to cell wall stress. Rlm1 is activated through a phosphorylation by Slt2, whereas the Swi4/Swi6 activation i
Autor:
Cliff, Chelsy L, Williams, Bethany, Chadjichristos, Christos E, Mouritzen, Ulrik, Squires, Paul E, Hills, Claire E
Of increasing prevalence, diabetes is characterised by elevated blood glucose and chronic inflammation that precedes the onset of multiple secondary complications, including those of the kidney and the eye. As the leading cause of end stage renal dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_________5::35ef2b041adb971656b88c35c7c0015b