Zobrazeno 1 - 10
of 71
pro vyhledávání: '"C1 complex"'
Autor:
Francesca Florio, Sara Vencato, Filomena T Papa, Michela Libergoli, Eyemen Kheir, Imen Ghzaiel, Thomas A Rando, Yvan Torrente, Stefano Biressi
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 12, Pp 1-20 (2023)
Abstract Fibrosis is associated with compromised muscle functionality in Duchenne muscular dystrophy (DMD). We report observations with tissues from dystrophic patients and mice supporting a model to explain fibrosis in DMD, which relies on the cross
Externí odkaz:
https://doaj.org/article/c9912217f8cc4e60b7661bc54ca1d39c
Autor:
Uday Kishore, Berhane Ghebrehiwet
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/e7a5db8dfd274505aa4f1d8b6537f53d
Akademický článek
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Publikováno v:
Frontiers in Immunology, Vol 5 (2014)
The classical complement pathway is initiated by the large (~800kDa) and flexible multimeric C1 complex. Its catalytic function is triggered by the hetero-tetramer of proteases C1r2s2, which is associated to the C1q sensing unit, a complex assembly o
Externí odkaz:
https://doaj.org/article/62e2478ec8ea4e929b67139f7a5c2c6a
Autor:
Uday Kishore, Berhane Ghebrehiwet
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in Immunology
Autor:
Kinga K Hosszu, Alisa eValentino, Yan eJi, Mara eMatkovic, Lina ePednekar, Nina eRehage, Nithin eTumma, Ellinor I.E. Peerschke, Berhane eGhebrehiwet
Publikováno v:
Frontiers in Immunology, Vol 3 (2012)
The synthesis of the subunits of the C1 complex (C1q, C1s, C1r), and its regulator C1 inhibitor (C1-Inh) by human monocytes has been previously established. However, surface expression of these molecules by monocytes has not been shown. Using flow cy
Externí odkaz:
https://doaj.org/article/038716c15c8e409a908d2455bda06b72
Autor:
Darrell Sawmiller, Paul R. Sanberg, Huayan Hou, Jin Zeng, Jun Tian, Manasa Kanithi, Dan Zi, Ahsan Habib, Zhi-Xu He, Jun Tan
Publikováno v:
Cell Transplantation, Vol 27 (2018)
Cell Transplantation
Cell Transplantation
Alzheimer’s Disease (AD) is the leading cause of dementia in the elderly. In healthy individuals, amyloid precursor protein (APP) is cleaved by α-secretase, generating soluble α-amyloid precursor protein (sAPPα), which contributes neuroprotectiv
Autor:
Zwarthoff, Seline
Infectious diseases are becoming harder to treat, since bacteria become multiresistant against antibiotics. It is therefore important to develop novel therapies against infections. One possibility is antibody therapy in which therapeutic antibodies a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6d7567e163fc93b6a3743cd0a4660949
https://dspace.library.uu.nl/handle/1874/385604
https://dspace.library.uu.nl/handle/1874/385604
Infectious diseases are becoming harder to treat, since bacteria become multiresistant against antibiotics. It is therefore important to develop novel therapies against infections. One possibility is antibody therapy in which therapeutic antibodies a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dris___00893::6f7f6548ae2b266802eef14d8fa44088
https://hdl.handle.net/1874/385604
https://hdl.handle.net/1874/385604
Akademický článek
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